E-resources
-
Lundin, C; Wikman, A; Lampa, E; Bixo, M; Gemzell‐Danielsson, K; Wikman, P; Ljung, R; Sundström Poromaa, I
BJOG, 20/May , Volume: 129, Issue: 6Journal Article
Objective To investigate whether users of hormonal contraceptives (HCs) are at increased risk of depression compared with non‐users. Design Register‐based cohort study. Setting Sweden. Sample Women aged 15–25 years between 2010 and 2017 with no prior antidepressant treatment, psychiatric diagnose or contraindication for HCs (n = 739 585). Methods Women with a prescription of HC were identified via the Swedish Prescribed Drug Register (SPDR). Relative risks (RRs) for first depression diagnosis in current HC‐users compared with non‐users were modelled by Poisson regression. Adjustments included age, medical indication for HC‐use and parental history of mental disorders, among others. Main outcome measures Depression, captured by a redeemed prescription of antidepressant treatment, or a first depression diagnosis in the SPDR and the National Patient Register. Results Compared with non‐users, women on combined oral contraceptives (COCs) and oral progestogen‐only products had lower or no increased risk of depression, relative risk (RR) 0.89 (95% CI 0.87–0.91) and 1.03 (95% CI 0.99–1.06) after adjustments, respectively. Age‐stratified analyses demonstrated that COC use in adolescents conferred no increase in risk (RR 0.96, 95% CI 0.93–0.98), whereas use of progestogen‐only pills (RR 1.13, 95% CI 1.07–1.19), contraceptive patch/vaginal ring (RR 1.43, 95% CI 1.30–1.58), implant (RR 1.38, 95% CI 1.30–1.45) or a levonorgestrel intrauterine device (RR 1.59, 95% CI 1.46–1.73) were associated with increased risks. Conclusions This study did not find any association between use of COCs, which is the dominating HC in first time users, and depression. Non‐oral products were associated with increased risks. Residual confounding must be addressed in the interpretation of the results. Tweetable There is no association between combined hormonal contraceptives and depression. Tweetable There is no association between combined hormonal contraceptives and depression.
Author
![loading ... loading ...](themes/default/img/ajax-loading.gif)
Shelf entry
Permalink
- URL:
Impact factor
Access to the JCR database is permitted only to users from Slovenia. Your current IP address is not on the list of IP addresses with access permission, and authentication with the relevant AAI accout is required.
Year | Impact factor | Edition | Category | Classification | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Select the library membership card:
If the library membership card is not in the list,
add a new one.
DRS, in which the journal is indexed
Database name | Field | Year |
---|
Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
---|
Source: Personal bibliographies
and: SICRIS
The material is available in full text. If you wish to order the material anyway, click the Continue button.