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Han, Jianxin; Chen, Xiaoyu; Liu, Wei; Cui, Hao; Yuan, Tao
Molecules (Basel, Switzerland), 01/2020, Volume: 25, Issue: 3Journal Article
A new triterpenoid saponin, named terpengustifol A ( ), and two new lignan glucosides, phengustifols A and B ( and ), were isolated from the flowers of . Their structures were determined by the extensive analysis of the spectroscopic data (including NMR and HRMS) and ECD calculations. Compound possesses an unusual monoterpene ( )-6-hydroxy-2,6-dimethylocta-2,7-dienoyl unit at C-21. Compounds and are a pair of diastereoisomers, while their aglycones are a pair of enantiomers. Compounds and exhibited moderate cytotoxic activities against A375 cell lines with IC values at 12.1 and 15.6 μM, respectively. This is firstly reported the triterpenoid saponin and lignans isolated from the flowers.
