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Thyroid volume changes during pregnancy and after delivery in an iodine-sufficient Republic of SloveniaFister, Petja ...Objective: Literature data concerning thyroid enlargement during pregnancy arenot conclusive. Our aim was to systematically follow the thyroid volume changes during pregnancy and after delivery in an ... iodine-sufficient area. Sudydesign: Prospective study of healthy pregnant women living in an iodine-sufficient area. We followed 118 pregnant women with the mean age 30.9+/-4.1 years in the first trimester (mean 11.2+/-2.5 weeks of pregnancy), in the third trimester (mean 31.6+/-1.7 weeks of pregnancy), and 4 months after delivery (mean 15.9+/-3.9 weeks). Additionally, 71 women were also evaluated 14 months after delivery (mean 13.3+/-1.1 months). All women were negative for thyroid autoantibodies. We measured urinary iodine concentration (UIC), thyroid volume, serum TSH, and body mass index (BMI). After delivery, in a subgroup of women we also estimated the colour flow Doppler sonography (CFDS) patterns 0, I, II and III, where thyroid vascularity increased from pattern 0 to III, and the peak systolic velocity (PSV) using a 7.5 mHz linear transducer. Results: Median UIC in the third trimester (176 microg/g creatinine) was significantly higher than 4 and 14 months after delivery (P=0.030, P<0.001, respectively). Thyroid volume in the third trimester (11.3+/-3.1 mL) was significantly greater (P<0.001) than in the first trimester (8.7+/-2.5 mL), 4 months after delivery (8.6+/-2.5) and 14 months after delivery (7.8+/-2.4 mL). TSH concentration was significantly higher in the third trimester than in the first trimester and 4 months after delivery (P=0.007, P=0.006, respectively). As expected, BMI was the highest in the third trimester. CFDS pattern I was more frequent 4 months after delivery than14 months after delivery (P<0.001). Similarly, PSV was significantly higher 4 months after delivery than 14 months after delivery (P<0.001). (Abstract truncat at 2000 characters)Vir: European Journal of Obstetrics, Gynecology and Reproductive Biology. - ISSN 0301-2115 (Letn. 145, št. 1, 2009, str. 45-48)Vrsta gradiva - članek, sestavni delLeto - 2009Jezik - angleškiCOBISS.SI-ID - 25690329
Avtor
Fister, Petja |
Gaberšček, Simona |
Zaletel, Katja |
Krhin, Blaž |
Geršak, Ksenija |
Hojker, Sergej
Teme
Thyroid Gland |
Ultrasonography |
Blood Supply |
Thyrotropin |
Blood |
Iodine |
Urine |
Body Mass Index |
Pregnancy |
Puerperium |
Prospective Studies |
Tirotropin |
Telesna masa, indeks |
Ščitnica |
Nosečnost |
Jod |
Prospektivne študije |
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Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
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Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
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Fister, Petja | 27756 |
Gaberšček, Simona | 11039 |
Zaletel, Katja | 20484 |
Krhin, Blaž | 20485 |
Geršak, Ksenija | 00814 |
Hojker, Sergej | 01900 |
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