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MF, Centralna medicinska knjižnica, Ljubljana (CMK)
Poletni urnik (1.7. do 31.8.2024): ponedeljek do četrtek: 9.00-15.00, petek: 9.00-13.00.
26.7., 15.8. in 16.8. 2024 bo knjižnica ZAPRTA.
  • The impact of acute COVID-19 on the retinal microvasculature assessed with multimodal imaging [Elektronski vir]
    Jevnikar, Kristina ...
    Purpose: to quantify retinal microvascular fndings in the acute phase of COVID-19 using multimodal imaging and compare them with healthy, age-matched controls. Methods: hospitalized patients in the ... acute phase of COVID-19 without known systemic comorbidities (n = 75) and healthy controls (n = 101) aged 18–65 were enrolled in this prospective cross-sectional study. The retinal microcirculation and microvasculature impairments were assessed using fundus photography, swept-source optical coherence tomography, and swept-source optical coherence tomography angiography in the COVID-19 unit and compared with healthy, age-matched controls. Results: retinal fndings were predominately observed in patients with severe disease (P=0.006). Patients with severe disease were shown to have increased both mean vein diameter (Coef.=19.28, 95% CI: 7.34–31.23, P=0.002) and mean artery diameter (Coef.=11.07, 95% CI: 0.84–21.67, P=0.044). Neither blood vessel diameters were correlated with any confounding variables (age, sex, treatment with oxygen, LDH, or ferritin). Patients with severe COVID-19 were shown to have signifcantly increased retinal nerve fber layer thickness in the superior and inferior quadrants both in the inner (S: P=0.046; I: P=0.016) and outer (S: P=0.026; I: P=0.014) ring and signifcantly increased GCL thickness in the outer temporal quadrant (P=0.038). There were no statistically signifcant diferences in vessel density or the foveal avascular zone area between the groups. Conclusion: the severity of COVID-19 was signifcantly correlated with the presence of retinal microangiopathy, which could become a biomarker of angiopathy in patients with COVID-19.
    Vir: Graefe's archive for clinical and experimental ophthalmology [Elektronski vir]. - ISSN 1435-702X (Vol. 261, no. , 2023, Str. 1115-1125)
    Vrsta gradiva - e-članek ; neleposlovje za odrasle
    Leto - 2022
    Jezik - angleški
    COBISS.SI-ID - 128333827

    Povezava(-e):

    https://link.springer.com/article/10.1007/s00417-022-05887-0

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    DOI

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