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  • D-dimer v diagnostiki pljučne embolije = D-dimer in the diagnostic procedure of pulmonary embolism
    Škrgat-Kristan, Sabina ...
    Background. D-dimer concentration is increased in pulmonary embolism (PE), deep vein thrombosis (DVT) and in many other diseases and conditions. In this study the usefulness of plasma D-dimer ... concentration measurement was assessed in differential diagnosis in patients with dyspnoea and suspected pulmonary embolism. Methods. In retrospective analysis 144 patients were included who had been examined due to dyspnoea. We measured their plasma D-dimer concentration with immunoturbidimetric test Turbiquant D-dimer (Behring Diagnostic GmbH). D-dimer concentration above 250 ug/L was considered as increased. Forty-one patients had also their plasma D-dimer concentration measured with SimpliRED D-dimer (AGEN Biomedical) test simultaneously. Patients with increased D-dimer concentration were classified into 8 groups, according to their final diagnosis. Diagnostic values of both tests were compared. Results. Among 144 patients there were 38 (26,4%) with D- dimer concentration 250 ug/L or less. Two of them had pulmonary embolism. One hundred and six (73. 6%)patients had D- dimer concentration above 250 ug/L. There was no statistical difference in concentration of D-dimer between the PEgroup and other groups of patients (p > 0.05). In 19 patients with negative SimpliRED D-dimer but positive Turbiquant D-dimer test, concentration of D-dimer was between 253 and 2640 ug/L. Conclusions. Values of D-dimer concentration above the cutoff value are of no help in differential diagnosis in patients with dyspnoea and suspected pulmonary embolism. Values of D-dimer concentration below cutoff value exclude pulmonary embolism with 95% probability. Cutoff value of SimpliRED D-dimer test isprobably higher than cutoff value of Turbiquant D-dimer test.
    Vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 68, št. 11, nov. 1999, str. 639-641)
    Vrsta gradiva - članek, sestavni del
    Leto - 1999
    Jezik - slovenski
    COBISS.SI-ID - 10992345

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