Akutna mieloblastna levkemija: retrospektivna analiza odraslih bolnikov, ki smo jih zdravili po protokolu MRC AML 10 = Acute myeloid leukemia: a retrospective analysis of MRC AML 10 treated adult patients
Preložnik Zupan, Irena, medicina
Background. Acute myeloid leukemias (AML) refer to a group of hematopoietic neoplasms involving cells commited to the myeloid line of cellular development. During the past 20 years the outcome of ...treatment of AML in younger patients has improved substantially. The general evolution in the therapeutic strategy has been a more aggresive treatment early in first complete remission. We report our experiences with MRC AML 10 treated petients. Methods. On the Department of Haematology in Ljubljana, 54 young adults AML patients (27 men, 27 women) were treated with MRC AML 10 protocol, from January 1994 to September 2000. The median age of the patients was 44 years. Results. At the end of the induction therapy 35 (65%) patients achievedcomplete remission (CR). 13 patients were transplanted (5 autologous, 8 allogeneic). The median of the overall survival was 11 months, the estimatedrate of survival at 3 years was 27%. The median relaps-free survival duration was 19 months. Conclusions. The optimum amount of treatment for youngadults patients with AML has not yet been defined in the literature. It is clear that autologous and allogeneic bone marrow transplantation (BMT) can further reduce the risk of relapse in all groups of patients. For BMT to achieve its potential, the technique must be made safer.
Bibliografsko gradivo je bilo uspešno dodano na polico.
Dodajanje bibliografskega gradiva na polico ni uspelo.
Gradivo je že na polici.
Trajna povezava
URL:
Faktor vpliva
Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
Leto
Faktor vpliva
Izdaja
Kategorija
Razvrstitev
JCR
SNIP
JCR
SNIP
JCR
SNIP
JCR
SNIP
Izberite knjižnično izkaznico:
Baze podatkov,
v katerih je revija indeksirana
Ime baze podatkov
Področje
Leto
Povezave do osebnih bibliografij avtorjev
Povezave do podatkov o raziskovalcih v sistemu SICRIS
Storitev za pridobivanje naslova trenutno ni dostopna, prosimo, poskusite še enkrat.
S klikom na gumb "V redu" boste potrdili zgoraj izbrano prevzemno mesto in dokončali postopek rezervacije.
S klikom na gumb "V redu" boste potrdili zgoraj izbrano prevzemno mesto in naslov za dostavo ter dokončali postopek rezervacije.
S klikom na gumb "V redu" boste potrdili zgoraj izbrani naslov za dostavo in dokončali postopek rezervacije.
Obvestilo
Trenutno je storitev za avtomatsko prijavo in rezervacijo nedostopna. Gradivo lahko rezervirate sami na portalu Biblos ali ponovno poskusite tukaj kasneje.
Citiranje
Funkcionalnost trenutno ni na voljo. Prosimo, poskusite kasneje.
Naročanje gradiva za izposojo v čitalnice
Naročanje kopij člankov
Urnik dostave gradiva z oznako DS v signaturi