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  • Motnje pretoka v mikrocirkulaciji pri bolnikih s kronično vensko insuficienco = Blood flow disturbances in patients with chronic venous insufficiency
    Mlačak, Blaž, zdravnik ...
    Background. The aim of this study was to investigate patients with clinical stages II and III of chronic venous insufficiency (CVI) by laser Doppler fluxmetry (LDF) in order asses whether these ... clinical entities correspond to specific flow regulation. Methods. 2 groups of subjects were incorporated in the study. The first group included 30 patients with CVI stage II or III, and the second (control) group included 30 persons with healthy veins of lower limbs. Microcirculation investigations were carried out at rest and after hemodynamics tests. Blood flow changes were measured by laser Doppler fluxmetry. Changes in the laser Doppler flux minus the "biological zero" valuewere measured after 3 minutes of arterial occlusion and by experimental venous hypertension (cuff pressure 70 mm Hg to provoke venoarteriolar reflex) and expressed relatively to the pretest resting value. Results. Resting LDF was significantly higher in the group I (patients with CVI II and CVI III stage) as compared to the group with healthy subjects (p<0,001). In patients (with CVI II and CVI III stage group I LDF) remained nearly unchanged after arterial occlusion (5.5% flow increase vs. 445% in the group II-healthy controls (p<0,001). Experimental venous hypertension (cuff press 70 mm Hg) ledto profound reduction of flux in both 2 groups (I-91.2%; II-90.5%). The venoarteriolar reflex (VAR) is not impaired in legs with CVI when compared to healthy legs. Conclusion. LD fluxmetry helps to distinguish patients with CVI stage II and III from healthy subjects, particulary when measurements are performed during reactive hyperemia test.
    Vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 69, št. 10, okt. 2000, str. 663-666)
    Vrsta gradiva - članek, sestavni del
    Leto - 2000
    Jezik - slovenski
    COBISS.SI-ID - 12461529

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