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  • Kombinirano zdravljenje bolnikov z benigno hiperplazijo prostate = Combination therapy in patients with benign prostatic hyperplasia
    Tršinar, Bojan
    Background The purpose of observational program of patients with lower urinarytract symptoms (LUTS) because of benign prostatic hyperplasia (BPH) (LUTS/BPH) was to acquire additional ... pharmaco-epidemiological data on the safety and efficacy of combination therapy with finasteride and tamsulosin. Methods Observational program of men with BPH was conducted in urological outpatient clinics in Slovenia from April 2004 until November 2005. In open-label, non-interventional program 1173 patients were observed, who had been treated because of LUTS/BPH with com bination therapy with finasteride and tamsulosin, in the framework of common treat meat. At baseline and after six months of treatment for each patient the International Prostatic Symptom Score (IPSS) questionnaire and assessment of quality of life (QL) were filled in. In addition, urinary flow rate and prostate volume were determined. Adverse effects of drugs were reported spontaneously. Forstatistical analysis the Student's t-test was performed. Results Combination therapy with finasteride and tamsulosin was well tolerated. 89 (7.6%) patients discontinuedwith medication because of lack of efficacy or because of adverse effects of drugs. Symptom score, assessment of quality of patients' lives and volume of prostates were significantly lower (p < 0.0001), while urinary flow rate was significantly higher (p < 0.0001) after six months of treatment with finasteride and tamsulosin.
    Vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 75, št. 11, nov. 2006, str. 697-701)
    Vrsta gradiva - članek, sestavni del
    Leto - 2006
    Jezik - slovenski
    COBISS.SI-ID - 21995225

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    Digitalna knjižnica Slovenije - dLib.si

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