Travellers' diarrhea is a major public health problem, contributing to significant morbidity and disability. Bacterial enteropathogens cause a majority of cases involving this form of diarrhea. ...Traveller's diarrhea affects over 50% of travellers to some destinations and can disrupt holidays and business trips. Diarrhea usually begins within the first two weeks of travel, symptoms last for three to four days. Although travelers may be given common sense advice of avoidance of high-risk food and other measures to prevent travellers' diarrhea, adherence to such advice is sometimes difficult and the evidence for its effectiveness is contradictory. However, non-antimicrobial means for prevention are favored in most setting. The aim oftreatment is to reduce the severity and the duration of symptoms. A simple stepwise approach to the management of travellers' diarrhea includes single dose or 3-day course of antimicrobials, often self administered. The antibiotics of choice are currently fluoroquinolones or azithromycin, with an emerging role of rifaximin. It appears possible to decrease the rate of illness among travellers by careful selection of food and beverage and throughchemoprophylaxis with rifaximin.
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