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  • Biokemijski označevalci nezgodne možganske okvare = Biochemical markers of traumatic brain injury
    Gradišek, Primož ...
    Background: Currently used clinical and radiological findings of particularly mild traumatic brain injury have limited diagnostic and prognostic value. Methods and results: We conducted a systematic ... review of selected primary clinical studies on biochemical markers of traumatic brain injury in the last 10 years, using an electronic search of the National Library of Medicinećs database MEDLINE. The most explored and clinically relevant biochemical markers of acute brain injury are protein S100B, neuron-specific enolase and glial fibrillary acidic protein. In addition, novel markers such as spectrin breakdown product, c-tau and amiloid-b are presented. Based on clinical trials, the rationale for their use in the context of severity of traumatic brain injury is outlined. Conclusions: Measurement of biochemical markers of brain injury should be introduced in the clinical management of mild traumaticbrain injury. The predictive value of current clinical and radiological findings can be markedly improved by the determination of biochemical markers in mild and severe traumatic brain injury.
    Vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 80, št. 4, apr. 2011, str. 293-301)
    Vrsta gradiva - članek, sestavni del
    Leto - 2011
    Jezik - slovenski
    COBISS.SI-ID - 28295385

    Povezava(-e):

    http://szd.si/user_files/vsebina/Zdravniski_Vestnik/2011/april/293-301.pdf
    Digitalna knjižnica Slovenije - dLib.si

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