Narodna in univerzitetna knjižnica, Ljubljana (NUK)
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Surfactant replacement theapy for severe neonatal respiratory distress syndrome: higher incidence of intracranial haemorrhage - consequence or coincidence? = Zdravljenje hude dihalne stiske novorojenčka s sulfraktantom: več možganskih krvavitev - posledica ali slučajnost?Babnik, Janez, 1949- ...Backround. Evaluation of the results of exogenous surfactant replacement therapy for neonatal respiratory distress syndrome and comparison with outcomes of previous treatment. Patients and methods. ... The group of treated neonates was enrolled in the international,Curosurf 4 trial. The inclusion criteria were the following: 1. respiratory distress detected clinically and with X-rays; 2. tracheal intubation and mechanical ventilation; 3. age: control group of neonates, born within 20 months before the study started, was selected using computer data, strictly following the same inclusion criteria as for the study group. Results. 33 neonates who underwent the surfactant, replacement therapy were compared to 36 neonates of the control group. After the first dose of surfactant the a/A oxygen ratio increased from 0.11 to 0.20 and FiO2 could be lowered from 0.80 to 0.60. Survival did not significantly differ between the groups (73% vs 69 %). Neonates treated with surfactant often had open ductus arteriosus (52% vs 25%), higher incidence of intracranial haemorrhage (61% vs 42%), however, on average they needed 5 days less of artificial ventilation and shorter treatment with oxygen. A higher incidence of intracranial haemorrhage in the study group is the result of coincidental selection of newborns with lowest gestational age (26.1 wks) and at the same time with the severest form of respiratory distress (a/A O2<0.07). Conclusions. The immediate effect of surfactant replacement therapy is the improvement of ventilation (increase of a/A O2 and decrease of the necessary FiO2). The final effect of treatment is shorter ventilation and shorter requirement for oxygen. A higher incidence of intracranial haemorrhage after the surfactant application results from a higher number of preterm infants with the severest form of respiratory distress syndrome in the study group.Vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Let. 65, št. 1, jan. 1996, str. 1-4)Vrsta gradiva - članek, sestavni delLeto - 1996Jezik - angleškiCOBISS.SI-ID - 4037081
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vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Let. 65, št. 1, jan. 1996, str. 1-4)
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Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
Ime baze podatkov | Področje | Leto |
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Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
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Babnik, Janez, 1949- | 05273 |
Kornhauser-Cerar, Lilijana, 1958- | 12176 |
Pestevšek, Maja | 12123 |
Vir: Osebne bibliografije
in: SICRIS
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Naročanje gradiva za izposojo v čitalnice
Naročanje kopij člankov
Urnik dostave gradiva z oznako DS v signaturi