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  • Mikroalbuminurija kot kazalnik periferne arterijske okluzivne bolezni pri diabetikih tipa 2 = Mikroalbuminuria as a marker of peripheral arterial occlusive disease in type 2 diabetics
    Mlačak, Blaž ...
    Background. More recent epidemiologic studies have determined that microalbuminuria and proteinuria are significant risk markers for the development of atherosclerosis. The aim of this study was to ... determine the frequency of microalbuminuria in patients with and without diabetes mellitus with a group which had arterial peripheral occlusive disease and microabluminuria. Patients and methods. The test group contained 60 patients with type II diabetes mellitus, between 28 and 87 years of age, 24 males and 36 females. The control groupconsisted of60 patients without diabetes, who were comparable to the test group by age, sex, and profession. Microalbuminuria was considered to be present if the albumin: creatinine ratiowas >- 2.5. Peripheral arterial occlusive disease was diagnosed in the lower extramities by Doppler a ultrasound. Results. Peripheral arterial occlusive disease was diagnosed in 26.7% of patients with diabetes mellitus, in 10% of the controlg group. The difference is statistically significant (P <0.05). In the diabetic group 19 (31.7%) had microalbuminuria but only 7 (11.7%) ofthe control group. In the presence of microalbuminuria the incidenceof arterial occlusive disease was 79%, but in those without it only 4.9%. The difference is statistically significant (P < 0.001). Conclusions. Our study has demonstrated that microalbuminuria is frequently present in diabetes mellitus and peripheral arterial occlusive disease. We are certainly justified in determining the presence of microalbuminuria in diabetes with theaim of early prevention and therapy.
    Vrsta gradiva - članek, sestavni del
    Leto - 1998
    Jezik - slovenski
    COBISS.SI-ID - 7878361