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  • The application of macromolecular contrast media to define the abnormal microvascular permeability in the temporomandibular joint by MRI = Uporaba makromolekularnih kontrastnih sredstev za določanje nenormalne prepustnosti malih žil v čeljustnem sklepu pri slikanju z magnetno resonanco
    Demšar, Franci ; Lestan, Boris ; Ivanuša, Teodora
    The application of magnetic resonance (MR) imaging in medicine represents a novel approach in the detection of fine tissue structure and organ function invivo. An improved enhacement of MR images is ... achieved by using paramagnetic contrast media. These substances enable faster relaxantion of water protons ina magnetic field, what is presented as a positive contrast anhancement at the sites where the medium is concentrated. Historically, small molecule contrast media were developed first.They were successfully used in different clinical research fields. Their property of rapid diffusion to the interstitial space rendered their use limited in further clinical exploitation. The development of macromolecular contract media (MMCM) enable these molecules to dwell inside the vascular compartment. Contrast-enhanced MRimaging is a useful tool for the detection of early inflammatory changes of joint tissues (like temporomandibular joint) and for the follow up therapeuticstrategies of affected joints.
    Vrsta gradiva - članek, sestavni del
    Leto - 1998
    Jezik - angleški
    COBISS.SI-ID - 7905497