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  • Angiosarcoma of the liver after multimodality therapy for gallbladder carcinoma = [Angiosarkom jeter po kombiniranem zdravljenju raka žolčnika]
    Botros, Maikel ; Quevedo, J. Fernando ; Miller, Robert C.
    Background. Treatment-induced angiosarcoma is a rare complication of cancer therapy and is best known for arising on the chest wall after a mastectomy. Wereport an unusual case of a treatment-induced ... angiosarcoma developing in theliver after adjuvant radiotherapy for gallbladder carcinoma. Case report. Radiation-induced angiosarcoma of the liver developed in a 46-year-old woman after radiotherapy for stage IIB (T3N1M0) adenocarcinoma of the gallbladder in1991. The patient subsequently underwent resection, postoperative external beam radiotherapy, and multiagent chemotherapy. Several severe late adverse effects developed, including duodenal obstruction with fistula formation and chronic mesenteric ischemia secondary to occlusion of the superior mesenteric artery. Six years after her gallbladder resection and adjuvant treatment, a fatal grade 4 of 4 angiosarcoma of the liver developed within the radiation field. Conclusions. To our knowledge, this is the first case of radiation-induced angiosarcoma of the liver after radiotherapy for gallbladdercarcinoma. Normal organ dose-volume limits should be considered carefully when delivering a course of external beam radiotherapy in the upper abdomen.
    Vir: Radiology and oncology. - ISSN 1318-2099 (Vol. 43, no. 2, 2009, str. 126-131)
    Vrsta gradiva - članek, sestavni del
    Leto - 2009
    Jezik - angleški
    COBISS.SI-ID - 25672921

    Povezava(-e):

    Digitalna knjižnica Slovenije - dLib.si

vir: Radiology and oncology. - ISSN 1318-2099 (Vol. 43, no. 2, 2009, str. 126-131)

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