Selective attention focuses visual processing on relevant stimuli in order to allow for adaptive behaviour despite an abundance of distracting information. It has been proposed that increases in ...alpha band (8–12 Hz) amplitude reflect an active mechanism for distractor suppression. If this were the case, increases in alpha band amplitude should be succeeded by a decrease in distractor processing. Surprisingly, this connection has not been tested directly; specifically, studies that have investigated changes in alpha band after attention-directing cues have not directly assessed the neuronal processing of distractors. We concurrently recorded alpha activity and steady-state visual evoked potentials (SSVEPs) to assess the processing of target and distractor stimuli. In two experiments, participants covertly shifted attention to one of two letter streams (left or right) to detect infrequent target letters ‘X’ while ignoring the other stream. In line with previous findings, alpha band amplitudes contralateral to the unattended location increased compared to a pre-cue baseline. However, there was no suppression of SSVEP amplitudes elicited by unattended stimuli, while there was a pronounced enhancement of SSVEPs elicited by attended stimuli. Furthermore, and crucially, changes in alpha band amplitude during attention shifts did not precede those in SSVEPs and hit rates in both experiments, indicating that changes in alpha band amplitudes are likely to be a consequence of attention shifts rather than the other way around. We conclude that these findings contradict the notion that alpha band activity reflects mechanisms that have a causal role in the allocation of selective attention.
•Alpha brain waves supposedly represent an active mechanism of selective attention.•Tested via EEG recordings of steady-state visual evoked potentials and alpha waves.•Alpha-enhancement did not lead to the suppression of distractor stimulus processing.•Stimulus processing and task performance changes were not preceded by alpha changes.•Selective attention shifts might lead to changes in alpha, not vice-versa.
Nonsense-mediated mRNA decay (NMD) is probably the best characterized eukaryotic RNA degradation pathway. Through intricate steps, a set of NMD factors recognize and degrade mRNAs with translation ...termination codons that are positioned in abnormal contexts. However, NMD is not only part of a general cellular quality control system that prevents the production of aberrant proteins. Mammalian cells also depend on NMD to dynamically adjust their transcriptomes and their proteomes to varying physiological conditions. In this Review, we discuss how NMD targets mRNAs, the types of mRNAs that are targeted, and the roles of NMD in cellular stress, differentiation and maturation processes.
Cortical networks that process colour and luminance signals are often studied separately, although colour appearance depends on both colour and luminance. In fact, objects in everyday life are very ...rarely defined by only colour or only luminance, necessitating an investigation into combined processing of these signals. We used steady-state visual evoked potentials (SSVEPs) to investigate (1) cortical summation of luminance and chromatic contrast and (2) attentional modulation of neural activity driven by competing stimuli that differ in chromoluminant content. Our stimuli combined fixed amounts of chromatic contrast from either of the two cone-opponent mechanisms (bluish and yellowish; reddish and greenish) with two different levels of positive luminance contrast. Our experiments found evidence of non-linear processing of combined colour and luminance signals, which most likely originates in V1-V3 neurons tuned to both colour and luminance. Differences between luminance contrast of stimuli were found to be a key determinant for the size of feature-based voluntary attentional effects in SSVEPs, with colours of lower contrast than the colour they were presented with receiving the highest level of attentional modulation. Our results indicate that colour and luminance contrast are processed interdependently, both in terms of perception and in terms of attentional selection, with a potential candidate mediating their link being stimulus appearance, which depends on both chromaticity and luminance.
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•SSVEPs reflect non-linear summation of cone-opponent and luminance signals.•Amplitude and phase cannot be predicted from a linear combination of single-mechanism responses.•Bluish sums differently with luminance when compared to other colours in both a perceptual and the attentional task.•Performance is also reduced for bluish stimuli.•Colour and luminance are processed interdependently in the cortex for the purposes of perception and attentional selection.
Research on attentional selection of stimulus features has yielded seemingly contradictory results. On the one hand, many experiments in humans and animals have observed a "global" facilitation of ...attended features across the entire visual field, even when spatial attention is focused on a single location. On the other hand, several event-related potential studies in humans reported that attended features are enhanced at the attended location only. The present experiment demonstrates that these conflicting results can be explained by differences in the timing of attentional allocation inside and outside the spatial focus of attention. Participants attended to fields of either red or blue randomly moving dots on either the left or right side of fixation with the task of detecting brief coherent motion targets. Recordings of steady-state visual evoked potentials elicited by the flickering stimuli allowed concurrent measurement of the time course of feature-selective attention in visual cortex on both the attended and the unattended sides. The onset of feature-selective attentional modulation on the attended side occurred around 150 ms earlier than on the unattended side. This finding that feature-selective attention is not spatially global from the outset but extends to unattended locations after a temporal delay resolves previous contradictions between studies finding global versus hierarchical selection of features and provides insight into the fundamental relationship between feature-based and location-based (spatial) attention mechanisms.
Steady-state visual evoked potentials (SSVEPs) are a powerful tool for investigating selective attention. Here, we conducted a combined reanalysis of multiple studies employing this technique in a ...variety of attentional experiments to, first, establish benchmark effect sizes of attention on amplitude and phase of SSVEPs and, second, harness the power of a large data set to test more specific hypotheses. Data of eight published SSVEP studies were combined, in which human participants (n = 135 in total) attended to flickering random dot stimuli based on their defining features (e.g., location, color, luminance, or orientation) or feature conjunctions. The reanalysis established that, in all the studies, attention reliably enhanced amplitudes, with color-based attention providing the strongest effect. In addition, the latency of SSVEPs elicited by attended stimuli was reduced by ∼4 msec. Next, we investigated the modulation of SSVEP amplitudes in a subset of studies where two different features were attended concurrently. Although most models assume that attentional effects of multiple features are combined additively, our results suggest that neuronal enhancement provided by concurrent attention is better described by multiplicative integration. Finally, we used the combined data set to demonstrate that the increase in trial-averaged SSVEP amplitudes with attention cannot be explained by increased synchronization of single-trial phases. Contrary to the prediction of the phase-locking account, the variance across trials of complex Fourier coefficients increases with attention, which is more consistent with boosting of a largely phase-locked signal embedded in non-phase-locked noise.
Keeping track of the location of multiple moving objects is one of the well documented functions of visual attention. However, the mechanism of attentional selection that supports such continuous ...tracking is unclear. In particular, it has been proposed that target selection in early visual cortex occurs in parallel, with tracking errors arising because of attentional limitations at later processing stages. Here, we examine whether, instead, total attentional capacity for enhancement of early visual processing of tracked targets is shared between all attended stimuli. If the magnitude of attentional facilitation of multiple tracked targets was a key limiting factor of tracking ability, then one should expect it to drop systematically with increasing set-size of tracked targets. Human observers (male and female) were instructed to track two, four, or six moving objects among a pool of identical distractors. Steady-state visual evoked potentials (SSVEPs) recorded during the tracking period revealed that the processing of tracked targets was consistently amplified compared with the processing of the distractors. The magnitude of this amplification decreased with increasing set size, and at lateral occipital electrodes it closely followed inverse proportionality to the number of tracked items, suggesting that limited attentional resources must be shared among the tracked stimuli. Accordingly, the magnitude of attentional facilitation predicted the behavioral outcome at the end of the trial. Together, these findings demonstrate that the limitations of multiple object tracking (MOT) across set-sizes stem from the limitations of top-down selective attention already at the early stages of visual processing.
The ability to selectively attend to relevant features or objects is the key to flexibility of perception and action in the continuously changing environment. This ability is demonstrated in the multiple object tracking (MOT) task where observers monitor multiple independently moving objects at different locations in the visual field. The role of early attentional enhancement in tracking was previously acknowledged in the literature, however, the limitations on tracking were thought to arise during later stages of processing. Here, we demonstrate that the strength of attentional facilitation depends on the number of tracked objects and predicts successful tracking performance. Thus, it is the limitations of attentional enhancement at the early stages of visual processing that determine behavioral performance limits.
Simulation of wind turbine wakes using the actuator line technique Sørensen, Jens N.; Mikkelsen, Robert F.; Henningson, Dan S. ...
Philosophical transactions of the Royal Society of London. Series A: Mathematical, physical, and engineering sciences,
02/2015, Letnik:
373, Številka:
2035
Journal Article
Recenzirano
Odprti dostop
The actuator line technique was introduced as a numerical tool to be employed in combination with large eddy simulations to enable the study of wakes and wake interaction in wind farms. The technique ...is today largely used for studying basic features of wakes as well as for making performance predictions of wind farms. In this paper, we give a short introduction to the wake problem and the actuator line methodology and present a study in which the technique is employed to determine the near-wake properties of wind turbines. The presented results include a comparison of experimental results of the wake characteristics of the flow around a three-bladed model wind turbine, the development of a simple analytical formula for determining the near-wake length behind a wind turbine and a detailed investigation of wake structures based on proper orthogonal decomposition analysis of numerically generated snapshots of the wake.
Directing attention to task-relevant stimuli is crucial for successful task performance, but too much attentional selectivity implies that new and unexpected information in the environment remains ...undetected. A possible mechanism for optimizing this fundamental trade-off could be an error monitoring system that immediately triggers attentional adjustments following the detection of behavioral errors. However, the existence of rapid adaptive post-error adjustments has been controversially debated. While preconscious error processing reflected by an error-related negativity (Ne/ERN) in the event-related potential has been shown to occur within milliseconds after errors, more recent studies concluded that error detection even impairs attentional selectivity and that adaptive adjustments are implemented, if at all, only after errors are consciously detected. Here, we employ steady-state visual evoked potentials elicited by continuously presented stimuli to precisely track the emergence of error-induced attentional adjustments. Our results indicate that errors lead to an immediate reallocation of attention towards task-relevant stimuli, which occurs simultaneously with the Ne/ERN. Single-trial variation of this adjustment was correlated with the Ne/ERN amplitude and predicted adaptive behavioral adjustments on the post-error trial. This suggests that early error monitoring in the medial frontal cortex is directly involved in eliciting adaptive attentional adjustments.
•SSVEPs were used to track the time course of attentional post-error adjustments.•Errors lead to an immediate allocation of attention to relevant stimuli.•Adjustments occur simultaneously with Ne/ERN and correlate with its amplitude.•Adjustments predict adaptive behavioral adjustments on post-error trial.
In natural vision, processing of spatial and nonspatial features occurs simultaneously; however, the two types of attention in charge of facilitating this processing have distinct mechanisms. Here, ...we tested the independence of spatial and feature-based attention at different stages of visual processing by examining color-based attentional selection while spatial attention was focused or divided. Human observers attended to one or two of four fields of randomly moving dots presented in both left and right visual hemifields. In the focused attention condition, the target stimulus was defined both by color and location, whereas in the divided attention condition stimuli of the target color had to be attended in both hemifields. Sustained attentional selection was measured by means of steady-state visual evoked potentials elicited by each of the frequency-tagged flickering dot fields. Additionally, target and distractor selection was assessed with ERPs to these stimuli. We found that spatial and color-based attention independently modulated the amplitude of steady-state visual evoked potentials, confirming independent top–down influences on early visual areas. In contrast, P3 amplitudes elicited only by targets and distractors of the attended color were subject to space-based enhancement, suggesting increasing integration of spatial and feature-based selection over the course of perceptual processing.
Selective attention can enhance the processing of attended features across the entire visual field. Attention also spreads within objects, enhancing all internal locations and task‐irrelevant ...features of selected objects. Here, we examine the extent to which attentional enhancement of a feature spreads across attended and unattended objects. Two fully overlapping counter‐rotating bicolored surfaces of light and dark random dots were presented on a gray background of intermediate luminance. This stimulus creates a percept of two separate semitransparent surfaces and allows the measurement of feature‐ and object‐based selections while controlling spatial attention. On each trial, human participants attended to a subset of dots defined by feature (luminance polarity) and object (surface) in order to detect brief episodes of radial motion while ignoring any events in the unattended groups of dots. Attentional selection was assessed by means of steady‐state visual evoked potentials (SSVEPs) and behavioral measures. SSVEP amplitudes recorded at medial occipital electrode sites were modulated both by surface‐based and luminance polarity‐based selection in a manner consistent with independent multiplicative enhancement of attentional effects in different dimensions in early visual cortex. This finding supports the view that feature‐based attention spreads across object boundaries, at least at an early stage of processing. However, SSVEPs elicited at more lateral electrode sites showed a hierarchical pattern of selection, potentially reflecting the binding of surface‐defining features with luminance features to enable surface‐based attention.
Selective attention enhances the processing of attended features across the visual field as well as all the features of attended objects. The current study tested how feature‐based attention interacts with object‐based attention. Steady‐state visual evoked potentials showed that at an early stage of processing feature‐based attention spreads across object boundaries.
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