Spins associated with single defects in solids provide promising qubits for quantum-information processing and quantum networks. Recent experiments have demonstrated long coherence times, ...high-fidelity operations, and long-range entanglement. However, control has so far been limited to a few qubits, with entangled states of three spins demonstrated. Realizing larger multiqubit registers is challenging due to the need for quantum gates that avoid cross talk and protect the coherence of the complete register. In this paper, we present novel decoherence-protected gates that combine dynamical decoupling of an electron spin with selective phase-controlled driving of nuclear spins. We use these gates to realize a ten-qubit quantum register consisting of the electron spin of a nitrogen-vacancy center and nine nuclear spins in diamond. We show that the register is fully connected by generating entanglement between all 45 possible qubit pairs and realize genuine multipartite entangled states with up to seven qubits. Finally, we investigate the register as a multiqubit memory. We demonstrate the protection of an arbitrary single-qubit state for over 75 s—the longest reported for a single solid-state qubit—and show that two-qubit entanglement can be preserved for over 10 s. Our results enable the control of large quantum registers with long coherence times and therefore open the door to advanced quantum algorithms and quantum networks with solid-state spin qubits.
Alpha-particle self-heating, the process of deuterium-tritium fusion reaction products depositing their kinetic energy locally within a fusion reaction region and thus increasing the temperature in ...the reacting region, is essential for achieving ignition in a fusion system. Here, we report new inertial confinement fusion experiments where the alpha-particle heating of the plasma is dominant with the fusion yield produced exceeding the fusion yield from the work done on the fuel (pressure times volume change) by a factor of two or more. These experiments have achieved the highest yield (26 ± 0.5 kJ) and stagnation pressures (approximate220 ± 40 Gbar) of any facility-based inertial confinement fusion experiments, although they are still short of the pressures required for ignition on the National Ignition Facility (~300-400 Gbar). These experiments put us in a new part of parameter space that has not been extensively studied so far because it lies between the no-alpha-particle-deposition regime and ignition.
Nuclear magnetic resonance (NMR) is a powerful method for determining the structure of molecules and proteins
. Whereas conventional NMR requires averaging over large ensembles, recent progress with ...single-spin quantum sensors
has created the prospect of magnetic imaging of individual molecules
. As an initial step towards this goal, isolated nuclear spins and spin pairs have been mapped
. However, large clusters of interacting spins-such as those found in molecules-result in highly complex spectra. Imaging these complex systems is challenging because it requires high spectral resolution and efficient spatial reconstruction with sub-ångström precision. Here we realize such atomic-scale imaging using a single nitrogen vacancy centre as a quantum sensor, and demonstrate it on a model system of 27 coupled
C nuclear spins in diamond. We present a multidimensional spectroscopy method that isolates individual nuclear-nuclear spin interactions with high spectral resolution (less than 80 millihertz) and high accuracy (2 millihertz). We show that these interactions encode the composition and inter-connectivity of the cluster, and develop methods to extract the three-dimensional structure of the cluster with sub-ångström resolution. Our results demonstrate a key capability towards magnetic imaging of individual molecules and other complex spin systems
.
Indirect-drive hohlraum experiments at the National Ignition Facility have demonstrated symmetric capsule implosions at unprecedented laser drive energies of 0.7 megajoule. One hundred and ninety-two ...simultaneously fired laser beams heat ignition-emulate hohlraums to radiation temperatures of 3.3 million kelvin, compressing 1.8-millimeter-diameter capsules by the soft x-rays produced by the hohlraum. Self-generated plasma optics gratings on either end of the hohlraum tune the laser power distribution in the hohlraum, which produces a symmetric x-ray drive as inferred from the shape of the capsule self-emission. These experiments indicate that the conditions are suitable for compressing deuterium-tritium-filled capsules, with the goal of achieving burning fusion plasmas and energy gain in the laboratory.
Laser redirection by cross-beam power transfer in a plasma is an important example of a nonlinear optics process which uses laser-plasma instabilities to one's advantage. We have demonstrated this in ...a hohlraum plasma at the National Ignition Facility (NIF) at Lawrence Livermore National Laboratory. A four-wave mixing process causes laser power in multiple beams to change direction and add to the laser power of a selected beam. The process is controlled by setting the wavelength separation of the interacting laser beams. This technique provides a method to remotely re-point or combine high-powered laser beams without the need of local optical apparatus. PUBLICATION ABSTRACT
Abstract
Solid-state spin qubits is a promising platform for quantum computation and quantum networks
1,2
. Recent experiments have demonstrated high-quality control over multi-qubit systems
3–8
, ...elementary quantum algorithms
8–11
and non-fault-tolerant error correction
12–14
. Large-scale systems will require using error-corrected logical qubits that are operated fault tolerantly, so that reliable computation becomes possible despite noisy operations
15–18
. Overcoming imperfections in this way remains an important outstanding challenge for quantum science
15,19–27
. Here, we demonstrate fault-tolerant operations on a logical qubit using spin qubits in diamond. Our approach is based on the five-qubit code with a recently discovered flag protocol that enables fault tolerance using a total of seven qubits
28–30
. We encode the logical qubit using a new protocol based on repeated multi-qubit measurements and show that it outperforms non-fault-tolerant encoding schemes. We then fault-tolerantly manipulate the logical qubit through a complete set of single-qubit Clifford gates. Finally, we demonstrate flagged stabilizer measurements with real-time processing of the outcomes. Such measurements are a primitive for fault-tolerant quantum error correction. Although future improvements in fidelity and the number of qubits will be required to suppress logical error rates below the physical error rates, our realization of fault-tolerant protocols on the logical-qubit level is a key step towards quantum information processing based on solid-state spins.
To examine the effect of changes in utilization and advances in cross-sectional imaging on radiologists' workload.
All computed tomography (CT) and magnetic resonance imaging (MRI) examinations ...performed at a single institution between 1999 and 2010 were identified and associated with the total number of images for each examination. Annual trends in institutional numbers of interpreted examinations and images were translated to changes in daily workload for the individual radiologist by normalizing to the number of dedicated daily CT and MRI work assignments, assuming a 255-day/8-hour work day schedule. Temporal changes in institutional and individual workload were assessed by Sen's slope analysis (Q = median slope) and Mann-Kendall test (Z = Z statistic).
From 1999 to 2010, a total of 1,517,149 cross-sectional imaging studies (CT = 994,471; MRI = 522,678) comprising 539,210,581 images (CT = 339,830,947; MRI = 199,379,634) were evaluated at our institution. Total annual cross-sectional studies steadily increased from 84,409 in 1999 to 147,336 in 2010, representing a twofold increase in workload (Q = 6465/year, Z = 4.2, P < .0001). Concomitantly, the number of annual departmental cross-sectional images interpreted increased from 9,294,140 in 1990 to 94,271,551 in 2010, representing a 10-fold increase (Q = 8707876/year, Z = 4.5, P < .0001). Adjusting for staffing changes, the number of images requiring interpretation per minute of every workday per staff radiologist increased from 2.9 in 1999 to 16.1 in 2010 (Q = 1.7/year, Z = 4.3, P < .0001).
Imaging volumes have grown at a disproportionate rate to imaging utilization increases at our institution. The average radiologist interpreting CT or MRI examinations must now interpret one image every 3-4 seconds in an 8-hour workday to meet workload demands.
In this 24-week trial, glucosamine and chondroitin sulfate were not more effective, alone or in combination, than placebo in controlling pain in patients with osteoarthritis of the knee. In secondary ...analyses, however, in the subgroup of patients with moderate-to-severe osteoarthritis, those given both glucosamine and chondroitin sulfate were more likely than those given placebo to have a decrease in pain (79 percent vs. 54 percent).
In this trial, glucosamine and chondroitin sulfate were not more effective, alone or in combination, than placebo in controlling pain in patients with osteoarthritis of the knee.
Osteoarthritis is the most common of the arthritides, affecting at least 20 million Americans, a number that is expected to double over the next two decades.
1
,
2
Currently available medical therapies primarily address the treatment of joint pain in patients with osteoarthritis.
3
Analgesics as well as traditional and cyclooxygenase-2–selective nonsteroidal antiinflammatory drugs (NSAIDs) have suboptimal effectiveness,
4
,
5
and there is some question about their safety, especially in the light of recent reports of increased cardiovascular risk.
6
–
8
The dietary supplements glucosamine and chondroitin sulfate have been advocated, especially in the lay media, as safe and effective options for the management . . .
ABSTRACT
The BRITICE‐CHRONO Project has generated a suite of recently published radiocarbon ages from deglacial sequences offshore in the Celtic and Irish seas and terrestrial cosmogenic nuclide and ...optically stimulated luminescence ages from adjacent onshore sites. All published data are integrated here with new geochronological data from Wales in a revised Bayesian analysis that enables reconstruction of ice retreat dynamics across the basin. Patterns and changes in the pace of deglaciation are conditioned more by topographic constraints and internal ice dynamics than by external controls. The data indicate a major but rapid and very short‐lived extensive thin ice advance of the Irish Sea Ice Stream (ISIS) more than 300 km south of St George's Channel to a marine calving margin at the shelf break at 25.5 ka; this may have been preceded by extensive ice accumulation plugging the constriction of St George's Channel. The release event between 25 and 26 ka is interpreted to have stimulated fast ice streaming and diverted ice to the west in the northern Irish Sea into the main axis of the marine ISIS away from terrestrial ice terminating in the English Midlands, a process initiating ice stagnation and the formation of an extensive dead ice landscape in the Midlands.
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