Since the first attempt that was made to obtain direct circularly polarized (CP) light from OLEDs by Meijer
et al.
in 1997, considerable efforts have been devoted to the development of circularly ...polarized organic light-emitting diodes (CP-OLEDs), particularly in the recent years. Circularly polarized electroluminescence (CPEL) based on OLEDs has attracted increasing interest for its efficient ability to generate CP light directly and wide potential applications in 3D displays, optical data storage, and optical spintronics. In this review, we systematically summarize the recent progress in chiral emitter based OLEDs with CPEL properties including CPEL based on chiral conjugated polymers, CPEL based on chiral metal complexes, and CPEL based on chiral simple organic molecules, especially chiral thermally activated delayed fluorescence (TADF) molecules. We believe that this review will provide a promising perspective of chiral emitter based OLEDs with CPEL properties for a broad range of scientists in different disciplinary areas and attract a growing number of researchers to this fast-growing research field.
This review summarizes the recent advances in CP-OLEDs based on chiral conjugated polymers, chiral metal complexes, and chiral simple organic molecules.
Graph is an important data representation which appears in a wide diversity of real-world scenarios. Effective graph analytics provides users a deeper understanding of what is behind the data, and ...thus can benefit a lot of useful applications such as node classification, node recommendation, link prediction, etc. However, most graph analytics methods suffer the high computation and space cost. Graph embedding is an effective yet efficient way to solve the graph analytics problem. It converts the graph data into a low dimensional space in which the graph structural information and graph properties are maximumly preserved. In this survey, we conduct a comprehensive review of the literature in graph embedding. We first introduce the formal definition of graph embedding as well as the related concepts. After that, we propose two taxonomies of graph embedding which correspond to what challenges exist in different graph embedding problem settings and how the existing work addresses these challenges in their solutions. Finally, we summarize the applications that graph embedding enables and suggest four promising future research directions in terms of computation efficiency, problem settings, techniques, and application scenarios.
In addition to a high specific capacitance, a large stretchability and self‐healing properties are also essential to improve the practicality and reliability of supercapacitors in portable and ...wearable electronics. However, the integration of multiple functions into one device remains challenging. Here, the construction of a highly stretchable and real‐time omni‐healable supercapacitor is demonstrated by sandwiching the polypyrrole‐incorporated gold nanoparticle/carbon nanotube (CNT)/poly(acrylamide) (GCP@PPy) hydrogel electrodes with a CNT‐free GCP (GP) hydrogel as the electrolyte and chemically soldering an Ag nanowire film to the hydrogel electrode as the current collector. The newly developed dynamic metal‐thiolate (M‐SR, M = Au, Ag) bond‐induced integrated configuration, with an intrinsically powerful electrode and electrolyte, enables the assembled supercapacitor to deliver an areal capacitance of 885 mF cm−2 and an energy density of 123 µWh cm−2, which are among the highest‐reported values for stretchable supercapacitors. Notably, the device exhibits a superhigh stretching strain of 800%, rapid optical healing capability, and significant real‐time healability during the charge–discharge process. The exceptional performance combined with the facile assembly method confirms this multifunctional device as the best performer among all the flexible supercapacitors reported to date.
A highly stretchable and real‐time omni‐healable supercapacitor is constructed by synergistically designing the entire device from the microstructures of the hydrogel electrode and electrolyte, to the interfacial interactions among the current collector, electrode, and electrolyte, and further to all‐in‐one device configuration via dynamic metal‐thiolate coordination chemistry. This supercapacitor shows great potential in the field of next‐generation flexible/wearable electronics.
The use of a chiral, emitting skeleton for axially chiral enantiomers showing activity in thermally activated delayed fluorescence (TADF) with circularly polarized electroluminescence (CPEL) is ...proposed. A pair of chiral stable enantiomers, (−)‐(S)‐Cz‐Ax‐CN and (+)‐(R)‐Cz‐Ax‐CN, was designed and synthesized. The enantiomers, both exhibiting intramolecular π‐conjugated charge transfer (CT) and spatial CT, show TADF activities with a small singlet–triplet energy difference (ΔEST) of 0.029 eV and mirror‐image circularly polarized luminescence (CPL) activities with large glum values. Notably, CP‐OLEDs based on the enantiomers feature blue electroluminescence centered at 468 nm with external quantum efficiencies (EQEs) of 12.5 and 12.7 %, and also show intense CPEL with gEL values of −1.2×10−2 and +1.4×10−2, respectively. These are the first CP‐OLEDs based on TADF‐active enantiomers with efficient blue CPEL.
Let's twist again: Axially chiral molecules with thermally activated delayed fluorescence and circularly polarized electroluminescence (CPEL) are presented. CP‐OLEDs based on these molecules display high efficiencies and blue CPEL with large gEL values.
Helicenes are polycyclic aromatic hydrocarbons having nonplanar screw-shaped skeletons. A study investigated the applications and synthesis of helicenes and the forms in which they have been ...developed.
Conspectus The development of new types of synthetic macrocyclic hosts is always one of the most important and attractive topics in macrocyclic and supramolecular chemistry. Calixarenes, ...resorcinarenes, cyclotriveratrylenes, pillararenes, and their analogues are all composed of hydroxy-substituted aromatic rings bridged by methylene or methenyl groups and thus can be considered a type of macrocyclic arenes. Because of their unique structural features, easy functionalization, and wide applications in many research areas, such macrocyclic arenes have become some of the most important and studied synthetic macrocyclic hosts during the last decades. Triptycene and its derivatives are a class of organic molecules having unique three-dimensional rigid structures, and they have proved to be useful building blocks for constructing new synthetic macrocyclic hosts with specific structures and properties. Dihydroxy-substituted triptycene derivatives are readily available compounds, which encouraged us to conduct studies of triptycene-derived macrocyclic arenes about 10 years ago. Consequently, a series of triptycene-derived calixarenes and analogues containing 1,8-dihydroxy-substituted triptycene subunits were conveniently synthesized. With 2,7-dihydroxy-substituted triptycene as a precursor, new types of calixarene, oxacalixarene, and homooxacalixarene analogues were also obtained. These triptycene-derived macrocyclic hosts all showed fixed conformations in solution and exhibited expanded cavities compared with the corresponding typical calixarenes and analogues. The special structural features also make these triptycene-derived macrocycles show wide potential applications in molecular recognition and self-assembly. In particular, it was found that the threading direction and the orientation based on macrocycles with nonsymmetric structures could be finely controlled by adjusting the electrostatic and steric effects of the guests, which could form the oriented 2rotaxane by unidirectional threading. We recently developed a new kind of chiral macrocyclic arenes named helicarenes that are composed of chiral 2,6-dihydroxy-substituted triptycene subunits bridged by methylene groups. It was found that the helicarenes not only exhibited convenient synthesis, high stability, good solubility, fixed conformations, and easy functionalization but also showed complexation abilities with various chiral and achiral organic guests. In particular, the switchable complexation based on these macrocycles could be efficiently controlled by multiple stimuli, including acid/base, redox, anion, or light stimuli under a photoacid. Moreover, the helicarenes have also found applications in the construction of interlocked molecules and molecular machines. This Account summarizes our recent research results on the synthesis and structures of the triptycene-derived macrocyclic arenes and analogues and their applications in host–guest chemistry and molecular assembly. We believe that these macrocyclic arenes, especially helicarenes, could be utilized as new synthetic hosts and find wide potential applications in macrocyclic and supramolecular chemistry.
An appropriate sample size is essential for obtaining a precise and reliable outcome of a study. In machine learning (ML), studies with inadequate samples suffer from overfitting of data and have a ...lower probability of producing true effects, while the increment in sample size increases the accuracy of prediction but may not cause a significant change after a certain sample size. Existing statistical approaches using standardized mean difference, effect size, and statistical power for determining sample size are potentially biased due to miscalculations or lack of experimental details. This study aims to design criteria for evaluating sample size in ML studies. We examined the average and grand effect sizes and the performance of five ML methods using simulated datasets and three real datasets to derive the criteria for sample size. We systematically increase the sample size, starting from 16, by randomly sampling and examine the impact of sample size on classifiers' performance and both effect sizes. Tenfold cross-validation was used to quantify the accuracy.
The results demonstrate that the effect sizes and the classification accuracies increase while the variances in effect sizes shrink with the increment of samples when the datasets have a good discriminative power between two classes. By contrast, indeterminate datasets had poor effect sizes and classification accuracies, which did not improve by increasing sample size in both simulated and real datasets. A good dataset exhibited a significant difference in average and grand effect sizes. We derived two criteria based on the above findings to assess a decided sample size by combining the effect size and the ML accuracy. The sample size is considered suitable when it has appropriate effect sizes (≥ 0.5) and ML accuracy (≥ 80%). After an appropriate sample size, the increment in samples will not benefit as it will not significantly change the effect size and accuracy, thereby resulting in a good cost-benefit ratio.
We believe that these practical criteria can be used as a reference for both the authors and editors to evaluate whether the selected sample size is adequate for a study.
Aromatic‐imide‐based thermally activated delayed fluorescent (TADF) enantiomers, (+)‐(S,S)‐CAI‐Cz and (−)‐(R,R)‐CAI‐Cz, were efficiently synthesized by introducing a chiral 1,2‐diaminocyclohexane to ...the achiral TADF unit. The TADF enantiomers exhibited high PLQYs of up to 98 %, small ΔEST values of 0.06 eV, as well as obvious temperature‐dependent transient PL spectra, thus demonstrating their excellent TADF properties. Moreover, the TADF enantiomers showed mirror‐image CD and CPL activities. Notably, the CP‐OLEDs with CPEL properties based on the TADF enantiomers not only achieved high EQE values of up to 19.7 and 19.8 %, but also displayed opposite CPEL signals with gEL values of −1.7×10−3 and 2.3×10−3, which represents the first CP‐OLEDs, based on the enantiomerically pure TADF materials, having both high efficiencies and intense CPEL.
It's intense: Thermally activated delayed fluorescenct (TADF) enantiomers were developed by introducing a chiral 1,2‐diaminocyclohexane to the achiral TADF unit. They exhibited high PLQYs (98 %), small ΔEST values (0.06 eV), and mirror‐image CD and CPL spectra. Moreover, they represent the first example of CP‐OLEDs, based on the enantiomerically pure TADF materials, having both high efficiencies (EQE: 19.8 %) and intense CPEL.
Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer featured with high intra-tumoral heterogeneity and poor prognosis. To comprehensively delineate the PDAC ...intra-tumoral heterogeneity and the underlying mechanism for PDAC progression, we employed single-cell RNA-seq (scRNA-seq) to acquire the transcriptomic atlas of 57,530 individual pancreatic cells from primary PDAC tumors and control pancreases, and identified diverse malignant and stromal cell types, including two ductal subtypes with abnormal and malignant gene expression profiles respectively, in PDAC. We found that the heterogenous malignant subtype was composed of several subpopulations with differential proliferative and migratory potentials. Cell trajectory analysis revealed that components of multiple tumor-related pathways and transcription factors (TFs) were differentially expressed along PDAC progression. Furthermore, we found a subset of ductal cells with unique proliferative features were associated with an inactivation state in tumor-infiltrating T cells, providing novel markers for the prediction of antitumor immune response. Together, our findings provide a valuable resource for deciphering the intra-tumoral heterogeneity in PDAC and uncover a connection between tumor intrinsic transcriptional state and T cell activation, suggesting potential biomarkers for anticancer treatment such as targeted therapy and immunotherapy.
A nonconventional U(1)e−μ gauge model is proposed to explain the observed neutrino masses and the unexpected anomalous magnetic moments of the electron and muon (lepton g−2), where for suppressing ...the neutrino coupling to Z′ gauge boson, only the right-handed electron and muon in the standard model carry the U(1)e−μ charge. Although the light lepton masses are suppressed when the gauge symmetry is spontaneously broken, they can be generated through the Yukawa couplings to newly introduced particles, such as vector-like lepton doublets and singlets, and scalar singlets. It is found that the same Yukawa couplings combined with the new scalar couplings to the Higgs can induce the radiative lepton-flavor violation processes ℓ′→ℓγ and lepton g−2, where the lepton g−2 is proportional to mℓ. When Majorana fermions and a scalar singlet are further added into the model, the active neutrinos can obtain masses via the radiative seesaw mechanism. When the bounds from the me and mμ and the neutrino data are satisfied, we find that the electron g−2 can reach an order of −10−12, and the muon g−2 can be an order of 10−9. In addition, when the μ→eγ decay is suppressed, the resulting branching ratio for τ→eγ can be of O(10−8), and that for τ→μγ can be as large as the current upper limit.
PDF
