The strategic alignment allows coordinating objectives, processes, resources, personnel and critical factors in order to make decision making viable, in addition, it allows aligning processes with ...the organization's strategy. The objective of the research is: to evaluate the strategic alignment between the processes and the strategic objectives in the Matanzas Provincial Sports Directorate. Tools such as: brainstorming, Kendall's Method, SWOT Matrix, Hierarchical Analytical Process were used. As results, the calculation of the strategic alignment index were obtained with a value of 7.13 and the index of alignment of relevant processes with 6.46, finding that organization is located in the first quadrant of the matrix, which means that the processes of the sports organization are aligned with the strategic objectives, 11 actions are recommended to mitigate the deficiencies detected and to continue with the deployment of the strategy for the Olympic cycle, which shows that the strategic alignment helps collaboration within the sports organization.
RESUMEN Los sistemas de gestión empresarial experimentan una notable transformación en los últimos años. Las exigencias de clientes/usuarios marcan el ritmo y la dirección de las organizaciones de ...gobierno deportivo, demanda más exigente, especializada y normativas cada vez más estrictas en el mercado internacional son de los factores que condicionan esta transformación dentro del sector deportivo. El objetivo de la investigación es analizar las principales tendencias de la gestión integrada. Se utilizaron métodos teóricos: histórico-lógico, análisis-síntesis e inductivo-deductivo y métodos empíricos: revisión bibliográfica y estratificación apoyados en herramientas informáticas como el software UCINET. Se obtiene que la gestión integrada se caracteriza por mejorar la integración del sistema organizacional para alcanzar los objetivos con eficiencia, eficacia y flexibilidad, y la aplicación de herramientas informáticas, en las etapas de planificación, operación, evaluación y mejora. El enfoque basado en la integración de procesos permite incorporar al sistema los requisitos unificados aplicables demandados por todas las partes interesadas, la determinación de las interacciones del proceso y la gestión de los agujeros negros. Este enfoque facilita a los actores involucrados el diseño e implementación de sistemas integrados normalizados y proporciona a la alta dirección un pensamiento sistémico para el análisis y la toma de decisiones.
Wounds represent a major healthcare problem especially in hospital-associated infections where multi-drug resistant strains are often involved. Nowadays, biomaterials with therapeutic molecules play ...an active role in wound healing and infection prevention. In this work, the development of collagen hydrogels loaded with silver nanoparticles and Cannabis sativa oil extract is described. The presence of the silver nanoparticles gives interesting feature to the biomaterial such as improved mechanical properties or resistance to collagenase degradation but most important is the long-lasting antimicrobial effect. Cannabis sativa oil, which is known for its anti-inflammatory and analgesic effects, possesses antioxidant activity and successfully improved the biocompatibility and also enhances the antimicrobial activity of the nanocomposite. Altogether, these results suggest that this novel nanocomposite biomaterial is a promising alternative to common treatments of wound infections and wound healing.
Background: Steatosis occurs frequently in hepatitis C. However, the mechanisms leading to this lesion are still unknown, and the role of steatosis in the progression of the disease remains ...controversial. The aim of the present paper was to determine the prevalence of steatosis in hepatitis C and its association with hepatitis C virus (HCV) genotype, viral load and the presence of risk factors for steatosis, and to analyze the association between steatosis and the intensity of liver disease.
Methods: Patients infected with HCV who underwent liver biopsy were included. Patients coinfected with hepatitis B virus and/or human immunodeficiency virus and those previously treated for hepatitis C were excluded. The following risk factors for steatosis were investigated: obesity (body mass index BMI > 25 kg/m2), diabetes mellitus, hyperlipidemia, alcoholism, and use of potential steatosis‐inducing drugs. Histological analysis evaluated the presence of steatosis, the degree of periportal activity and staging. Patients with and without steatosis were compared regarding demographic, epidemiological, laboratory and histological characteristics. Logistic regression analysis was applied to identify variables that were independently associated with the presence of steatosis.
Results: Ninety patients (55 men, 35 women) with a mean age of 45 ± 13 years were included. The prevalence of steatosis was 67%. Variables that remained independently associated with steatosis were age, female gender, obesity and genotype 3.
Conclusions: The prevalence of steatosis in hepatitis C was high. Risk factors usually related to steatosis such as age, female gender and obesity, as well as genotype 3, were independently associated with the presence of steatosis. Steatosis was not independently associated with the intensity of histological liver disease.
Background:Steatosis occurs frequently in hepatitis C. However, the mechanisms leading to this lesion are still unknown, and the role of steatosis in the progression of the disease remains ...controversial. The aim of the present paper was to determine the prevalence of steatosis in hepatitis C and its association with hepatitis C virus (HCV) genotype, viral load and the presence of risk factors for steatosis, and to analyze the association between steatosis and the intensity of liver disease. Methods:Patients infected with HCV who underwent liver biopsy were included. Patients coinfected with hepatitis B virus and-or human immunodeficiency virus and those previously treated for hepatitis C were excluded. The following risk factors for steatosis were investigated: obesity (body mass index BMI > 25 kg-m super(2)), diabetes mellitus, hyperlipidemia, alcoholism, and use of potential steatosis-inducing drugs. Histological analysis evaluated the presence of steatosis, the degree of periportal activity and staging. Patients with and without steatosis were compared regarding demographic, epidemiological, laboratory and histological characteristics. Logistic regression analysis was applied to identify variables that were independently associated with the presence of steatosis. Results:Ninety patients (55 men, 35 women) with a mean age of 45 plus or minus 13 years were included. The prevalence of steatosis was 67%. Variables that remained independently associated with steatosis were age, female gender, obesity and genotype 3. Conclusions:The prevalence of steatosis in hepatitis C was high. Risk factors usually related to steatosis such as age, female gender and obesity, as well as genotype 3, were independently associated with the presence of steatosis. Steatosis was not independently associated with the intensity of histological liver disease.
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