Multi-annual simulations over the Central America CORDEX domain are conducted with the latest version of regional climate model RegCM4 driven by ERA-Interim reanalysis fields. The RegCM4 system can ...reproduce both the annual cycle and the spatial patterns of mean summer precipitation over Central America and Mexico. Regional circulation features are also reproduced, although the intensity of the Caribbean Low-Level Jet is underestimated and it is located too far south. Over most land areas, RegCM4 surface air temperatures are lower than observations by 1 to 3°C, which however may also be related to biases in the reanalysis forcing data. The model can realistically simulate the amplitude of the convective diurnal cycle in areas where the convective triggering is dominated by non-local gravity wave effects. However, the simulation of the phase of the diurnal cycle of convection is less satisfactory, with the peak precipitation occurring earlier than observed, a common fault in atmospheric models. Sensitivity experiments are carried out to investigate the model sensitivity to land surface and a prognostic diurnal sea surface temperature scheme. Use of the Community Land Model (CLM) instead of the Bio sphere-Atmosphere Transfer Scheme (BATS) results in a warmer and drier land surface and a better simulation of the seasonal average spatial pattern of precipitation. However, with BATS, RegCM4 has a more realistic simulation of the mid-summer drought over the region. The impact of the prognostic sea surface temperature (SST) scheme is generally small. In general, neither of these surface physics upgrades results in a clearly superior model performance.
THE hereditary elliptocytosis syndrome encompasses a heterogeneous group of inherited disorders, the common feature of which is the presence of elliptical red cells on peripheral-blood film.
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...Recently, molecular defects of spectrin and protein 4.1, the principal proteins of the red-cell-membrane skeleton, were identified in many people with hereditary elliptocytosis.
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Hereditary elliptocytosis is uncommon in Westerners. A related condition, designated Southeast Asian ovalocytosis or stomatocytic elliptocytosis,
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is widespread in parts of Southeast Asia, particularly in Malaysia, Papua New Guinea, the Philippines, and Indonesia,
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with a prevalence reaching 30 percent in certain ethnic groups.
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The condition has recently attracted considerable attention for . . .
Of 1471 sera collected from 1986 to 1989 in Papua New Guinea (PNG), 2.2% were found to be positive for anti‐HTLV‐1 antibody by successive particle agglutination and immunofluorescence tests. The ...seropositive rate varied in different provinces and was higher in the coastal areas of the main island and in neighboring small islands than in the highlands of PNG. The frequency of HTLV‐1 infection of children was higher, but the age‐dependent increase in antibody positivity, generally observed in other HTLV‐1 endemic areas of the world, was not clear in PNG. No difference was observed in antibody prevalence in males and females in this study.
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