ABSTRACT
The deep, wide-area (∼800–900 arcmin
2
) near-infrared/WFC3/IR +
Spitzer
/IRAC observations over the CANDELS fields have been a remarkable resource for constraining the bright end of ...high-redshift UV luminosity functions. However, the lack of
Hubble Space Telescope
(
HST
) 1.05
μ
m observations over the CANDELS fields has made it difficult to identify
z
∼ 9–10 sources robustly, since such data are needed to confirm the presence of an abrupt Lyman break at 1.2
μ
m. Here, we report on the successful identification of many such
z
∼ 9–10 sources from a new
HST
program (z9-CANDELS) that targets the highest-probability
z
∼ 9–10 galaxy candidates with observations at 1.05
μ
m, to search for a robust Lyman-break at 1.2
μ
m. The potential
z
∼ 9–10 candidates were preselected from the full
HST
,
Spitzer
/IRAC S-CANDELS observations, and the deepest-available ground-based optical+near-infrared observations (CFHTLS-DEEP+HUGS+UltraVISTA+ZFOURGE). We identified 15 credible
z
∼ 9–10 galaxies over the CANDELS fields. Nine of these galaxies lie at
z
∼ 9 and five are new identifications. Our targeted follow-up strategy has proven to be very efficient in making use of scarce
HST
time to secure a reliable sample of
z
∼ 9–10 galaxies. Through extensive simulations, we replicate the selection process for our sample (both the preselection and follow-up) and use it to improve current estimates for the volume density of bright
z
∼ 9 and
z
∼ 10 galaxies. The volume densities we find are 5
and
lower, respectively, than those found at
z
∼ 8. When compared with the best-fit evolution (i.e.,
) in the UV luminosity densities from
z
∼ 8 to
z
∼ 4 integrated to
(−20 mag), these luminosity densities are
and
lower, respectively, than the extrapolated trends. Our new results are broadly consistent with the “accelerated evolution” scenario at
z
> 8, consistent with that seen in many models.
Sagittarius A* (Sgr A*) is the variable radio, near-infrared (NIR), and X-ray source associated with accretion onto the Galactic center black hole. We present an analysis of the most comprehensive ...NIR variability data set of Sgr A* to date: eight 24 hr epochs of continuous monitoring of Sgr A* at 4.5 m with the IRAC instrument on the Spitzer Space Telescope, 93 epochs of 2.18 m data from Naos Conica at the Very Large Telescope, and 30 epochs of 2.12 m data from the NIRC2 camera at the Keck Observatory, in total 94,929 measurements. A new approximate Bayesian computation method for fitting the first-order structure function extracts information beyond current fast Fourier transformation (FFT) methods of power spectral density (PSD) estimation. With a combined fit of the data of all three observatories, the characteristic coherence timescale of Sgr A* is minutes (90% credible interval). The PSD has no detectable features on timescales down to 8.5 minutes (95% credible level), which is the ISCO orbital frequency for a dimensionless spin parameter a = 0.92. One light curve measured simultaneously at 2.12 and 4.5 m during a low flux-density phase gave a spectral index s = 1.6 0.1 ( ). This value implies that the Sgr A* NIR color becomes bluer during higher flux-density phases. The probability densities of flux densities of the combined data sets are best fit by log-normal distributions. Based on these distributions, the Sgr A* spectral energy distribution is consistent with synchrotron radiation from a non-thermal electron population from below 20 GHz through the NIR.
Abstract
Sagittarius A* (Sgr A*) is the variable radio, near-infrared (NIR), and X-ray source associated with accretion onto the Galactic center black hole. We have analyzed a comprehensive ...submillimeter (including new observations simultaneous with NIR monitoring), NIR, and 2–8 keV data set. Submillimeter variations tend to lag those in the NIR by ∼30 minutes. An approximate Bayesian computation fit to the X-ray first-order structure function shows significantly less power at short timescales in the X-rays than in the NIR. Less X-ray variability at short timescales, combined with the observed NIR–X-ray correlations, means the variability can be described as the result of two strictly correlated stochastic processes, the X-ray process being the low-pass-filtered version of the NIR process. The NIR–X-ray linkage suggests a simple radiative model: a compact, self-absorbed synchrotron sphere with high-frequency cutoff close to NIR frequencies plus a synchrotron self-Compton scattering component at higher frequencies. This model, with parameters fit to the submillimeter, NIR, and X-ray structure functions, reproduces the observed flux densities at all wavelengths, the statistical properties of all light curves, and the time lags between bands. The fit also gives reasonable values for physical parameters such as magnetic flux density
B
≈ 13 G, source size
L
≈ 2.2
R
S
, and high-energy electron density
n
e
≈ 4 × 10
7
cm
−3
. An animation illustrates typical light curves, and we make public the parameter chain of our Bayesian analysis, the model implementation, and the visualization code.
ABSTRACT We present Hubble WFC3/IR slitless grism spectra of a remarkably bright z 10 galaxy candidate, GN-z11, identified initially from CANDELS/GOODS-N imaging data. A significant spectroscopic ...continuum break is detected at . The new grism data, combined with the photometric data, rule out all plausible lower redshift solutions for this source. The only viable solution is that this continuum break is the Ly break redshifted to , just ∼400 Myr after the Big Bang. This observation extends the current spectroscopic frontier by 150 Myr to well before the Planck (instantaneous) cosmic reionization peak at z ∼ 8.8, demonstrating that galaxy build-up was well underway early in the reionization epoch at z > 10. GN-z11 is remarkably, and unexpectedly, luminous for a galaxy at such an early time: its UV luminosity is 3× larger than measured at z ∼ 6−8. The Spitzer IRAC detections up to 4.5 m of this galaxy are consistent with a stellar mass of ∼109 M . This spectroscopic redshift measurement suggests that James Webb Space Telescope (JWST) will be able to similarly and easily confirm such sources at z > 10 and characterize their physical properties through detailed spectroscopy. Furthermore, WFIRST, with its wide-field near-IR imaging, would find large numbers of similar galaxies and contribute greatly to JWST's spectroscopy, if it is launched early enough to overlap with JWST.
Background and purpose
The role of lifestyle and dietary habits and antecedent events has not been clearly identified in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP).
Methods
...Information was collected about modifiable environmental factors and antecedent infections and vaccinations in patients with CIDP included in an Italian CIDP Database. Only patients who reported not having changed their diet or the lifestyle habits investigated in the study after the appearance of CIDP were included. The partners of patients with CIDP were chosen as controls. Gender‐matched analysis was performed with randomly selected controls with a 1:1 ratio of patients and controls.
Results
Dietary and lifestyle data of 323 patients and 266 controls were available. A total of 195 cases and 195 sex‐matched controls were used in the analysis. Patients eating rice at least three times per week or eating fish at least once per week appeared to be at decreased risk of acquiring CIDP. Data on antecedent events were collected in 411 patients. Antecedent events within 1–42 days before CIDP onset were reported by 15.5% of the patients, including infections in 12% and vaccinations in 1.5%. Patients with CIDP and antecedent infections more often had an acute onset of CIDP and cranial nerve involvement than those without these antecedent events.
Conclusions
The results of this preliminary study seem to indicate that some dietary habits may influence the risk of CIDP and that antecedent infections may have an impact on the onset and clinical presentation of the disease.
Abstract
Funding Acknowledgements
Type of funding sources: None.
Background
Metabolic syndrome associated with elevated fasting triglyceridemia (TG) is often associated with insomnia. The new ...guidelines of ESC for dyslipidemia advice the statin and/or ezetimibe treatment like fist line therapy in patients with hypertriglyceridemia, also before then fibrates or omega 3.
We examined the impact of rosuvastatin/ezetimibe treatment in reduction of insomnia in patents with hypertriglyceridemia.
Methods
In this study was enrolled a group of 148 patients with hypertriglyceridemia and insomnia. Patients were screened for severe insomnia, defined by a score of four or more on the three Hamilton Depression Rating Scale (HDRS) sleep items, and for HTG characterized by TG≥200mg/dL. The duration of sleep was evaluated with smartwatch every 7 days.
Mean age was 61,12 years. All patient was admitted in ambulatory of cardiology and were in wash out treatment for dyslipidaemic syndrome. In all we added 20 mg of rosuvastatin plus 10 mg of ezetimibe daily to therapy and reassessed patients after 30 days.
Results
Rosuvastatin/ezetimibe treatment was effective as add-on therapy in reduction of insomnia . All treated patients reported an improvement in symptoms. After 30 days, insomnia disappeared in 69% of patients and was reduced in 21% of patients.
The number of the sleeping hours improved from 5:35 min to 7:25 minutes.
Therapy was well tolerated in 99% of patents, and stopped only in 2 cases.
Conclusions
Our initial experience with rosuvastatin/ezetimibe in hypertriglyceridemia treatment suggests that this therapy may play a role in the treatment of insomnia
We give an introduction to several regularization schemes that deal with ultraviolet and infrared singularities appearing in higher-order computations in quantum field theories. Comparing the ...computation of simple quantities in the various schemes, we point out similarities and differences between them.
Emission from Saggitarius A* is highly variable at both X-ray and infrared (IR) wavelengths. Observations over the last ∼20 yr have revealed X-ray flares that rise above a quiescent thermal ...background about once per day, while faint X-ray flares from Sgr A* are undetectable below the constant thermal emission. In contrast, the IR emission of Sgr A* is observed to be continuously variable. Recently, simultaneous observations have indicated a rise in IR flux density around the same time as every distinct X-ray flare, while the opposite is not always true (peaks in the IR emission may not be coincident with an X-ray flare). Characterizing the behavior of these simultaneous X-ray/IR events and measuring any time lag between them can constrain models of Sgr A*'s accretion flow and the flare emission mechanism. Using 100+ hours of data from a coordinated campaign between the Spitzer Space Telescope and the Chandra X-ray Observatory, we present results of the longest simultaneous IR and X-ray observations of Sgr A* taken to date. The cross-correlation between the IR and X-ray light curves in this unprecedented data set, which includes four modest X-ray/IR flares, indicates that flaring in the X-ray may lead the IR by approximately 10-20 min with 68% confidence. However, the 99.7% confidence interval on the time-lag also includes zero, i.e., the flaring remains statistically consistent with simultaneity. Long-duration and simultaneous multi-wavelength observations of additional bright flares will improve our ability to constrain the flare timing characteristics and emission mechanisms, and must be a priority for Galactic Center observing campaigns.
Spontaneous Raman spectroscopy is a powerful characterization tool for graphene research. Its extension to the coherent regime, despite the large nonlinear third-order susceptibility of graphene, has ...so far proven challenging. Due to its gapless nature, several interfering electronic and phononic transitions concur to generate its optical response, preventing to retrieve spectral profiles analogous to those of spontaneous Raman. Here we report stimulated Raman spectroscopy of the G-phonon in single and multi-layer graphene, through coherent anti-Stokes Raman Scattering. The nonlinear signal is dominated by a vibrationally non-resonant background, obscuring the Raman lineshape. We demonstrate that the vibrationally resonant coherent anti-Stokes Raman Scattering peak can be measured by reducing the temporal overlap of the laser excitation pulses, suppressing the vibrationally non-resonant background. We model the spectra, taking into account the electronically resonant nature of both. We show how coherent anti-Stokes Raman Scattering can be used for graphene imaging with vibrational sensitivity.
In order to understand the nature of the sources producing the recently uncovered cosmic infrared background (CIB) fluctuations, we study cross-correlations between the fluctuations in the ...source-subtracted CIB from Spitzer/IRAC data and the unresolved cosmic X-ray background from deep Chandra observations. Our study uses data from the EGS/AEGIS field, where both data sets cover an Asymptotically = to8' x 45' region of the sky. Our measurement is the cross-power spectrum between the IR and X-ray data. The cross-power signal between the IRAC maps at 3.6 mum and 4.5 mum and the Chandra 0.5-2 keV data has been detected, at angular scales > ~20", with an overall significance of Asymptotically = to3.8sigma and Asymptotically = to5.6sigma, respectively. At the same time we find no evidence of significant cross-correlations at the harder Chandra bands. The cross-correlation signal is produced by individual IR sources with 3.6 mum and 4.5 mum magnitudes m sub(AB) > ~ 25-26 and 0.5-2 keV X-ray fluxes <<7 x 10 super(-17) erg cm super(2) s super(-1). We determine that at least 15%-25% of the large scale power of the CIB fluctuations is correlated with the spatial power spectrum of the X-ray fluctuations. If this correlation is attributed to emission from accretion processes at both IR and X-ray wavelengths, this implies a much higher fraction of accreting black holes than among the known populations. We discuss the various possible origins for the cross-power signal and show that neither local foregrounds nor the known remaining normal galaxies and active galactic nuclei can reproduce the measurements. These observational results are an important new constraint on theoretical modeling of the near-IR CIB fluctuations.
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