A large part of the physics program of the PANDA experiment at FAIR deals with the search for new conventional and exotic hadronic states like e.g. hybrids and glueballs. For many analyses PANDA will ...need an amplitude analysis, e.g. a partial wave analysis (PWA), to identify possible candidates and for the classification of known states. Therefore, a new, agile and efficient amplitude analysis framework ComPWA is under development. It is modularized to provide easy extension with models and formalisms as well as fitting of multiple datasets, even from different experiments. Experience from existing PWA programs was used to fix the requirements of the framework and to prevent it from restrictions. It will provide the standard estimation and optimization routines like Minuit2 and the Geneva library and be open to insert additional ones. The challenges involve parallelization, fitting with a high number of free parameters, managing complex meta-fits and quality assurance / comparability of fits. To test and develop the software, it will be used with data from running experiments like BaBar or BESIII. These proceedings show the status of the framework implementation as well as first test results.
Offline Software for the PANDA Luminosity Detector Karavdina, A; Denig, A; Feldbauer, F ...
Journal of physics. Conference series,
06/2014, Letnik:
513, Številka:
2
Journal Article, Conference Proceeding
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In 2018 data taking for hadronphysics facility PANDA is planned to commence. It will be build at the antiproton accelerator HESR, which itself is a part of the FAIR complex (GSI, Darmstadt, Germany). ...The luminosity at PANDA will be measured by a dedicated sub-detector, which will register scattered antiproton tracks from pp elastic scattering. From a software point of view, the Luminosity Detector is a tracking system. Therefore the most of its offline software parts are typical for a track reconstruction. The basic concept and Monte Carlo based performance studies of each reconstruction step is presented in this paper.
In 2018 data taking for hadronphysics facility PANDA is planned to commence. It will be build at the antiproton accelerator HESR, which itself is a part of the FAIR complex (GSI, Darmstadt, Germany). ...The luminosity at PANDA will be measured by a dedicated sub-detector, which will register scattered antiproton tracks from pp elastic scattering. From a software point of view, the Luminosity Detector is a tracking system. Therefore the most of its offline software parts are typical for a track reconstruction. The basic concept and Monte Carlo based performance studies of each reconstruction step is presented in this paper.
Phys. Rev. Lett. 115, 221805 (2015) We report the first absolute measurement of the branching fraction of
$\Lambda^+_{c}\rightarrow \Lambda e^+\nu_e$. This measurement is based on 567
pb$^{-1}$ of ...$e^+e^-$ annihilation data produced at $\sqrt{s}=4.599$ GeV, which
is just above the $\Lambda^+_c\bar{\Lambda}^-_c$ threshold. The data were
collected with the BESIII detector at the BEPCII storage rings. The branching
fraction is determined to be $\mathcal B({\Lambda^+_c\rightarrow \Lambda
e^+\nu_e})=(3.63\pm0.38({\rm stat})\pm0.20({\rm syst}))\%$, representing a more
than twofold improvement in precision upon previously published results. As the
branching fraction for $\Lambda^+_{c}\rightarrow \Lambda e^+\nu_e$ is the
benchmark for those of other $\Lambda^+_c$ semileptonic channels, our result
provides a unique test of different theoretical models, which is the most
stringent to date.
We report the first absolute measurement of the branching fraction of \(\Lambda^+_{c}\rightarrow \Lambda e^+\nu_e\). This measurement is based on 567 pb\(^{-1}\) of \(e^+e^-\) annihilation data ...produced at \(\sqrt{s}=4.599\) GeV, which is just above the \(\Lambda^+_c\bar{\Lambda}^-_c\) threshold. The data were collected with the BESIII detector at the BEPCII storage rings. The branching fraction is determined to be \(\mathcal B({\Lambda^+_c\rightarrow \Lambda e^+\nu_e})=(3.63\pm0.38({\rm stat})\pm0.20({\rm syst}))\%\), representing a more than twofold improvement in precision upon previously published results. As the branching fraction for \(\Lambda^+_{c}\rightarrow \Lambda e^+\nu_e\) is the benchmark for those of other \(\Lambda^+_c\) semileptonic channels, our result provides a unique test of different theoretical models, which is the most stringent to date.
Atomic resolution structures of cys-loop receptors, including one of a γ-aminobutyric acid type A receptor (GABAA receptor) subtype, allow amazing insights into the structural features and ...conformational changes that these pentameric ligand-gated ion channels (pLGICs) display. Here we present a comprehensive analysis of more than 30 cys-loop receptor structures of homologous proteins that revealed several allosteric binding sites not previously described in GABAA receptors. These novel binding sites were examined in GABAA receptor homology models and assessed as putative candidate sites for allosteric ligands. Four so far undescribed putative ligand binding sites were proposed for follow up studies based on their presence in the GABAA receptor homology models. A comprehensive analysis of conserved structural features in GABAA and glycine receptors (GlyRs), the glutamate gated ion channel, the bacterial homologs Erwinia chrysanthemi (ELIC) and Gloeobacter violaceus GLIC, and the serotonin type 3 (5-HT3) receptor was performed. The conserved features were integrated into a master alignment that led to improved homology models. The large fragment of the intracellular domain that is present in the structure of the 5-HT3 receptor was utilized to generate GABAA receptor models with a corresponding intracellular domain fragment. Results of mutational and photoaffinity ligand studies in GABAA receptors were analyzed in the light of the model structures. This led to an assignment of candidate ligands to two proposed novel pockets, candidate binding sites for furosemide and neurosteroids in the trans-membrane domain were identified. The homology models can serve as hypotheses generators, and some previously controversial structural interpretations of biochemical data can be resolved in the light of the presented multi-template approach to comparative modeling. Crystal and cryo-EM microscopic structures of the closest homologs that were solved in different conformational states provided important insights into structural rearrangements of binding sites during conformational transitions. The impact of structural variation and conformational motion on the shape of the investigated binding sites was analyzed. Rules for best template and alignment choice were obtained and can generally be applied to modeling of cys-loop receptors. Overall, we provide an updated structure based view of ligand binding sites present in GABAA receptors.
SciPy is an open-source scientific computing library for the Python programming language. Since its initial release in 2001, SciPy has become a de facto standard for leveraging scientific algorithms ...in Python, with over 600 unique code contributors, thousands of dependent packages, over 100,000 dependent repositories and millions of downloads per year. In this work, we provide an overview of the capabilities and development practices of SciPy 1.0 and highlight some recent technical developments.
The 3rd Aquatic Ecosystem MOdeling Network—Junior (AEMON-J) Hacking Limnology Workshop and 4th Virtual Summit: Incorporating Data Science and Open Science in the Aquatic Sciences (DSOS) took place ...24–28 July 2023. Furthermore, this joint event followed a similar structure to previous years, comprising three days of workshops followed by two days of the virtual summit. During the week, over 100 aquatic science practitioners and enthusiasts gathered to exchange knowledge and to share experiences working in the nexus of data science, open science, remote sensing, and the aquatic sciences.
The 2nd Aquatic Ecosystem Modeling-Junior (AEMON-J) Hacking Limnology Workshop and 3rd Virtual Summit: Incorporating Data Science and Open Science in the Aquatic Sciences (DSOS) took place on 25–29 ...July 2022. These virtual events were developed to bring together researchers from diverse backgrounds to share developments in data-intensive research in the aquatic sciences and train participants in cutting-edge data analysis methods related to remote sensing, data pipelines, and modeling of aquatic ecosystems.
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