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Trenutno NISTE avtorizirani za dostop do e-virov UL. Za polni dostop se PRIJAVITE.

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zadetkov: 279
1.
  • Allosteric modulation of ni... Allosteric modulation of nicotinic acetylcholine receptors
    Bertrand, Daniel; Gopalakrishnan, Murali Biochemical pharmacology, 10/2007, Letnik: 74, Številka: 8
    Journal Article
    Recenzirano

    Allosteric modulation refers to the concept that proteins could exist in multiple conformational states and that binding of allosteric ligands alters the energy barriers or “isomerization ...
Celotno besedilo
Dostopno za: UL
2.
Celotno besedilo
Dostopno za: UL
3.
  • Short-term oral gavage admi... Short-term oral gavage administration of adenine induces a model of fibrotic kidney disease in rats
    Zhu, Chang Z.; Doyle, Kelly J.; Nikkel, Arthur L. ... Journal of pharmacological and toxicological methods, November-December 2018, 2018 Nov - Dec, 2018-11-00, 20181101, Letnik: 94, Številka: Pt 1
    Journal Article
    Recenzirano

    The adenine model of kidney disease typically involves dietary delivery of adenine over several weeks. This model can be variable in its disease progression and can result in significant mortality. ...
Celotno besedilo
Dostopno za: UL
4.
  • Potassium channels: molecul... Potassium channels: molecular defects, diseases, and therapeutic opportunities
    Shieh, C C; Coghlan, M; Sullivan, J P ... Pharmacological reviews, 12/2000, Letnik: 52, Številka: 4
    Journal Article
    Recenzirano

    Potassium channels play important roles in vital cellular signaling processes in both excitable and nonexcitable cells. Over 50 human genes encoding various K(+) channels have been cloned during the ...
Celotno besedilo
Dostopno za: UL
5.
  • α7 nAChR-mediated activatio... α7 nAChR-mediated activation of MAP kinase pathways in PC12 cells
    Gubbins, Earl J; Gopalakrishnan, Murali; Li, Jinhe Brain research, 04/2010, Letnik: 1328
    Journal Article
    Recenzirano

    Abstract The α7 nicotinic acetylcholine receptor (α7 nAChR) plays a fundamental role in Ca2+ -dependent activation of signaling pathways that can modulate intracellular events involved in learning ...
Celotno besedilo
Dostopno za: UL
6.
  • Securitization of refugees ... Securitization of refugees in South Asia: Through the prism of Kautilya’s Arthashastra
    Gopalakrishnan, Murali Asian journal of comparative politics, 12/2020, Letnik: 5, Številka: 4
    Journal Article

    The acceptance of refugees and internally displaced persons represents the altruism of the countries of South Asia, which has witnessed the phenomenon of displaced persons since the early 19th ...
Celotno besedilo
Dostopno za: ODKLJ, UL
7.
Celotno besedilo
8.
  • High content screen microsc... High content screen microscopy analysis of Aβ1–42 -induced neurite outgrowth reduction in rat primary cortical neurons: Neuroprotective effects of α7 neuronal nicotinic acetylcholine receptor ligands
    Hu, Min; Schurdak, Mark E; Puttfarcken, Pamela S ... Brain research, 09/2007, Letnik: 1151
    Journal Article
    Recenzirano

    Abstract β-Amyloid peptide 1–42 (Aβ1–42 ) is generated from amyloid precursor protein (APP) and associated with neurodegeneration in Alzheimer's disease (AD). Aβ1–42 has been shown to be cytotoxic ...
Celotno besedilo
Dostopno za: UL
9.
Celotno besedilo
10.
  • SAR of α7 nicotinic recepto... SAR of α7 nicotinic receptor agonists derived from tilorone: Exploration of a novel nicotinic pharmacophore
    Schrimpf, Michael R.; Sippy, Kevin B.; Briggs, Clark A. ... Bioorganic & medicinal chemistry letters, 02/2012, Letnik: 22, Številka: 4
    Journal Article
    Recenzirano

    The well-known interferon-inducer tilorone was found to possess potent affinity for the agonist site of the α7 neuronal nicotinic receptor (Ki=56nM). SAR investigations determined that both basic ...
Celotno besedilo
Dostopno za: UL
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zadetkov: 279

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