On March 14, 1967, Adorno wrote a letter to Gershom Scholem, the great historian of Jewish mysticism, in which he sought to explain the idea of a negative dialectic. “In the immanent epistemological ...debate,” Adorno wrote, “once one has escaped from the clutches of idealism, what I call the primacy of the object . . . seems to me an attempt to do justice to the concept of materialism. The telling arguments that I believe I have advanced against idealism present themselves as materialist. But the materialism involved here is no conclusive, fixed thing, it is not a worldview. This path
Negative Dialectics Gordon, Peter E
Adorno and Existence,
11/2016
Book Chapter
In the autumn of 1965, during the final stages of preparation for his book on negative dialectics, Adorno offered a series of lectures on the same topic. In the lecture of November 30, he recalled ...the critical arguments from The Jargon of Authenticity, and he confessed to his auditors that criticism of that sort would not suffice. The sociological polemic of the earlier book had served the necessary purpose of disenchantment, breaking the aura of sanctity surrounding the philosophy of existence. “But of course,” Adorno hastened to explain, “in such situations it is never enough just to make a critical case;
Pioneers in South African Anaesthesia Hofmeyr, R; Gordon, PC
Southern African journal of anaesthesia and analgesia,
20/1/1/, Letnik:
19, Številka:
5
Journal Article
This paper uses commuting times and distance data from the Nationwide Personal Transportation Studies of 1977 to 1983-4 to re-evaluate the spatial mismatch hypothesis. Neither minorities nor ...low-income workers have longer commutes. In fact, their commuting patterns are very similar to those of workers in general. This also implies that minorities are not constrained by income or housing to live closer to work. However, women consistently have shorter worktrips. The spatial mismatch hypothesis receives no support from examination of commuting data.
Mechanistic analyses of nuclear pre-mRNA splicing
by the spliceosome and group II intron self-splicing provide
insight into both the catalytic strategies of splicing
and the evolutionary ...relationships between the different
splicing systems. We previously showed that 3′-sulfur
substitution at the 3′ splice site of a nuclear pre-mRNA
has no effect on splicing. We now report that 3′-sulfur
substitution at the 3′ splice site of a nuclear pre-mRNA
causes a switch in metal specificity when the second step
of splicing is monitored using a bimolecular exon-ligation
assay. This suggests that the spliceosome uses a catalytic
metal ion to stabilize the 3′-oxyanion leaving group
during the second step of splicing, as shown previously
for the first step. The lack of a metal-specificity switch
under cis splicing conditions indicates that a
rate-limiting conformational change between the two steps
of splicing may mask the subsequent chemical step and the
metal-specificity switch. As the group II intron, a true
ribozyme, uses identical catalytic strategies for splicing,
our results strengthen the argument that the spliceosome
is an RNA catalyst that shares a common molecular ancestor
with group II introns.
From humble beginnings, the Department of Anaesthesia of the University of Cape Town has played a major role in the development of anaesthesia as a speciality, in South Africa and internationally. We ...highlight these contributions in clinical service, teaching and research, with particular emphasis on the department's leading role in the evolution of anaesthetic safety in adults and children: from the development of the treatment of malignant hyperthermia, to unique studies in mortality associated with anaesthesia, and modern contributions to improved drug safety. Innovations in anaesthetic techniques have contributed to significant surgical developments, including the first heart transplant. Furthermore, our research has contributed to major advances in obstetric and endocrine anaesthesia, and training in the department is recognised as being among the best in the world.
Rail transit systems in modern American cities typically underperform. In light of high costs and low ridership, the cost-benefit results have been poor. But advocates often suggest that external ...(non-rider) benefits could soften these conclusions. In this paper we include recently published estimates of such non-rider benefits in the cost-benefit analysis. Adding these to recently published data for costs and ridership, we examine 34 post-World War II U.S. rail transit systems (8 commuter rail, 6 heavy rail and 20 light rail). The inclusion of the non-rider benefits does not change the negative assessment. In fact, sensitivity analyses that double the estimated non-rider benefits and/or double transit ridership also leave us with poor performance readings. Advocates who suggest that there are still other benefits that we have not included (always a possibility) have a high hurdle to clear.
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