Roman Imperial Portraits Dataset (ripd) Heijnen, Sam; Hekster, Olivier; Hermsen, Thijs
Research data journal for the humanities and social sciences,
06/2022, Letnik:
7, Številka:
1
Journal Article
Recenzirano
Abstract
Portraits of the Roman emperors have been a focal point in the study of the ancient world. However, questions on how this medium developed over time and/or how perceptions of the emperor ...changed over more than four centuries of imperial rule, are constrained by the availability and accessibility of the material. This article introduces the Roman Imperial Portraits Dataset (
ripd
) to allow researchers to study the portraiture of Roman emperors through a more quantitative approach (Heijnen & Hekster, 2021). The dataset has systematically brought together more than 2,100 extant (i.e. published) portraits of the Roman emperors into a single dataset that can be used for further study. The article also introduces a web application with the aim to allow researchers and interested parties to work with the data(set) in an user-friendly manner.
High levels of enantioselectivity have been achieved in the diethylzinc addition to both aromatic and aliphatic aldehydes, employing readily available
...N-substituted-azetidinyl(diphenylmethyl)methanols as chiral catalysts.
Graphic
A single intraperitoneal administration of zymosan induces multiple organ dysfunction syndrome (MODS) in C57BL/6 mice. The authors investigated the effect of a monoclonal antibody V1q against murine ...tumour necrosis factor α (TNF-α) on the development of zymosan-induced MODS and on plasma concentrations and the production capacity of interleukin 6 (IL-6) by peritoneal cells.
C57BL/6 mice received doses of V1q starting either simultaneously with administration of zymosan every four days, or from 4 or 8 days after administration of zymosan onwards. The animals were monitored for survival, condition, and body weight and temperature. Twelve days after zymosan all surviving animals were killed to obtain plasma, organs and peritoneal cells. Plasma concentrations of IL-6 and lipopolysaccharide-stimulated production of IL-6 by peritoneal cells were measured; organs were weighed as an indicator for organ damage and lung damage was assessed macroscopically.
Survival improved when the animals were treated with V1q starting at either time point , and a subpopulation developed from the group receiving V1q from day 0 onwards that displayed improved body weight and temperature when compared to the animals receiving zymosan only. Also, the wet organ weights improved in this subgroup, indicating a beneficial effect of the monoclonal antibody. However, V1q administered could neither decrease the circulating IL-6 concentrations toward control values, nor did V1q treatment normalize IL-6 production capacity (stimulated or unstimulated).
The development of zymosan-induced MODS can be attenuated by the monoclonal antibody V1q.
