As hydrogen, deuterium and tritium storage materials, a series of investigations of mechanical and thermal properties of titanium hydrides, deuterides and tritides have been performed, however, very ...limited theoretical studies of thermodynamic properties for them can be found. Based on density-functional theory (DFT) and density-functional perturbation theory (DFPT) we have discussed systematically the hydrogen isotope effects on the thermodynamic properties of TiX2 (X=H, D, and T) system. Our calculations indicate that for evaluating accurately their physical properties at absolute zero temperature, such as the equilibrium lattice constants, bulk modulus, and heat of formation, the zero-point energy correction must be taken into account. By performing the phonon calculation within quasiharmonic approximation (QHA), we obtain their vibrational free energies, vibrational entropies, and temperature dependence of specific heat, thermal expansion, and bulk modulus. Those results demonstrate that comparing with TiH2, TiT2 and TiD2 are more stable and the zero-point effects play an important role in their thermal expansion. The increase in the force constant between Ti and H causes the higher value of specific heat of TiH2 during the phase transition from FCC to FCT. In addition, comparing with available experimental values, we can conclude that QHA is feasible for describing the thermal properties of TiX2.
To evaluate clinical outcomes of autologous (auto-HSCT) and allogeneic hematopoietic stem cell transplantation (allo-HSCT) for angioimmunoblastic T-cell lymphoma (AITL) .
From June 2007 to June 2017, ...clinical data of AITL patients who underwent HSCT in eight hospitals were assessed retrospectively.
Of 19 patients, 13 male and 6 female with a median age of 50 (32-60) years old, 12 auto-HSCT and 7 allo-HSCT recipients were enrolled in this study, all donors were HLA-identical siblings. Two of allo-HSCT recipients were relapsed auto-HSCT ones. There were 5 patients (5/12) in complete response (CR) status and 7 (7/12) in partial remission (PR) status before transplantation in auto-HSCT group, and 2 (2/7) in PR status and 3 (3/7) in progression disease (PD) status before transplantation in allo-HSCT group. The median follow-up for the surviving patients was 46.5 months (range, 1-100 months) for the whole series, two patients lost in auto-HSCT group. Three patients developed acute graft-versus-host disease (aGVHD)
The pathophysiology of negative affect states in older adults is complex, and a host of central nervous system and peripheral systemic mechanisms may play primary or contributing roles. We conducted ...an unbiased analysis of 146 plasma analytes in a multiplex biochemical biomarker study in relation to number of depressive symptoms endorsed by 566 participants in the Alzheimer's Disease Neuroimaging Initiative (ADNI) at their baseline and 1-year assessments. Analytes that were most highly associated with depressive symptoms included hepatocyte growth factor, insulin polypeptides, pregnancy-associated plasma protein-A and vascular endothelial growth factor. Separate regression models assessed contributions of past history of psychiatric illness, antidepressant or other psychotropic medicine, apolipoprotein E genotype, body mass index, serum glucose and cerebrospinal fluid (CSF) τ and amyloid levels, and none of these values significantly attenuated the main effects of the candidate analyte levels for depressive symptoms score. Ensemble machine learning with Random Forests found good accuracy (~80%) in classifying groups with and without depressive symptoms. These data begin to identify biochemical biomarkers of depressive symptoms in older adults that may be useful in investigations of pathophysiological mechanisms of depression in aging and neurodegenerative dementias and as targets of novel treatment approaches.
Magnesium matrix composites reinforced with two volume fractions (1 and 3%) of SiC particles (1 μm) were successfully fabricated by ultrasonic vibration. Compared with as-cast AZ91 alloy, with the ...addition of the SiC particles grain size of matrix decreased, while most of the phase Mg
17
Al
12
varied from coarse plates to lamellar precipitates in the SiCp/AZ91 composites. With increasing volume fraction of the SiC particles, grains of matrix in the SiCp/AZ91 composites were gradually refined. The SiC particles were located mainly at grain boundaries in both 1 vol% SiCp/AZ91 composite and 3 vol% SiCp/AZ91 composite. SiC particles inside the particle clusters may be still separated by magnesium. The study of the interface between the SiC particle and the alloy matrix suggested that SiC particles bonded well with the alloy matrix without interfacial reaction. The ultimate tensile strength, yield strength, and elongation to fracture of the SiCp/AZ91 composites were simultaneously improved compared with that of the as-cast AZ91 alloy.
Liu YM, Liu YK, Wang LW, et al. Onco Targets Ther.2016;9:6651-6661. The authors have advised that the image used for Figure 3E,Panel 0 Gy 1.0 on page 6657, is incorrect. The correctFigure 3 is shown ...below. The authors have advised Figure 5 on page 6658 is alsoincorrect. The image was intended to present all the resultsfrom the same cellular experiments in one image. To dothis some adjustments were made to the Western blotbands to fit them into the same columns for drugconcentration, radiation dose and time. This did meansome bands were rearranged and moved from their positionsin the original Western blots. The upper bands whichinclude pchk2, p-ATM, Rad51, KU70 and KU80 were partof the original experiments and the lower bands whichinclude Cyclin B1, Cdc 2, p 21 and r-H2AX were addedfollowing peer review. The incorrect actin band wasshown for the lower Western blots and the correct Figure5 is shown below. The authors apologize for these errors. Read the original article
Controlling the formation of longitudinal cracks on hypo-peritectic steel slab surfaces is one of the key challenges in continuous casting worldwide. Based on the production in Chongqing Iron & Steel ...Co., mould fluxes with high basicity ranging from 1.7 to 1.8 were put forward and the effects of compositions on the basic properties of mould flux were studied in the present paper. After laboratory experiments, a high-basicity mould flux with an increased crystallisation speed to abate the heat-transfer capability in the meniscus area was fully applied in the first steelmaking plant of Chongqing Iron & Steel Co. Using the high-basicity mould flux, for more than 3 million tonnes of slab production, the large longitudinal crack was eliminated and the rate of formation of small longitudinal cracks decreased greatly. During the production process, sticking that impedes the smooth running of continuous casting was infrequent, and the spot check for longitudinal cracks on micro alloy steel surface was simplified in the slab finishing process. Furthermore, since the application effect of mass production is remarkable, the hot charging process is better implemented, and the contract can be accomplished in time. In summary, the problem of longitudinal cracks on hypo-peritectic steel slab surfaces is finally resolved and the high-basicity mould fluxes have become indispensable auxiliary materials during continuous casting of hypo-peritectic steel.
We present the measurements of all-particle energy spectrum and mean logarithmic mass of cosmic rays in the energy range of 0.3-30 PeV using data collected from LHAASO-KM2A between September 2021 and ...December 2022, which is based on a nearly composition-independent energy reconstruction method, achieving unprecedented accuracy. Our analysis reveals the position of the knee at 3.67±0.05±0.15 PeV. Below the knee, the spectral index is found to be -2.7413±0.0004±0.0050, while above the knee, it is -3.128±0.005±0.027, with the sharpness of the transition measured with a statistical error of 2%. The mean logarithmic mass of cosmic rays is almost heavier than helium in the whole measured energy range. It decreases from 1.7 at 0.3 PeV to 1.3 at 3 PeV, representing a 24% decline following a power law with an index of -0.1200±0.0003±0.0341. This is equivalent to an increase in abundance of light components. Above the knee, the mean logarithmic mass exhibits a power law trend towards heavier components, which is reversal to the behavior observed in the all-particle energy spectrum. Additionally, the knee position and the change in power-law index are approximately the same. These findings suggest that the knee observed in the all-particle spectrum corresponds to the knee of the light component, rather than the medium-heavy components.
In this study, the effects of Portulaca oleracea L. on blood and egg lipid of Dongxiang dark chickens was investigated. Forty-eight Dongxiang dark chickens with good physical condition and peak of ...egg production were selected. They were divided into four treatments, three replicates for each treatment with four chickens per replicate according to the principle of body weight and the number of eggs produced. Four diets adding Portulaca oleracea L. of different dose with 0%, 1%, 2% and 3% were fed for 35d, respectively. Eggs were collected from 25d until the end of the experiment, and venous blood was collected on 35d. The results showed that total cholesterol (TC), triglyceride (TG) in serum and cholesterol content in eggs with adding 2% Portulaca oleracea L. was significantly lower than those in the control (0%) while docosahexaenoic acid (DHA) content was significantly higher than the control (P<0.05). The contents of TC, TG and low-density lipoprotein (LDL) in serum of 3% Portulaca oleracea L. was significantly lower than the control, while high density lipoprotein (HDL) and linolenic acid and DHA in eggs was significantly higher than the control (P <0.05). In addition, the eicosapentaenoic acid (EPA) content in eggs with Portulaca oleracea L. was significantly higher than that of the control (P<0.05). Therefore, the addition of suitable Portulaca oleracea L. in the diet could change the lipid content in serum and eggs of laying hens.
ABSTRACT This paper reports on the measurement of the large-scale anisotropy in the distribution of cosmic-ray arrival directions using the data collected by the air shower detector ARGO-YBJ from ...2008 January to 2009 December, during the minimum of solar activity between cycles 23 and 24. In this period, more than 2 × 1011 showers were recorded with energies between ∼1 and 30 TeV. The observed two-dimensional distribution of cosmic rays is characterized by two wide regions of excess and deficit, respectively, both of relative intensity ∼10−3 with respect to a uniform flux, superimposed on smaller size structures. The harmonic analysis shows that the large-scale cosmic-ray relative intensity as a function of R.A. can be described by the first and second terms of a Fouries series. The high event statistics allow the study of the energy dependence of the anistropy, showing that the amplitude increases with energy, with a maximum intensity at ∼10 TeV, and then decreases while the phase slowly shifts toward lower values of R.A. with increasing energy. The ARGO-YBJ data provide accurate observations over more than a decade of energy around this feature of the anisotropy spectrum.
Data transformation is a popular option in training neural networks. This study evaluates the effectiveness of two well-known transformation methods: linear transformation and statistical ...standardization. These two are referred to as data standardization. A carefully designed experiment is used in which data from two-group classification problems were trained by feedforward networks. Different kinds of classification problems, from relatively simple to hard, were generated. Other experimental factors include network architecture, sample size, and sample proportion of group 1 members. Three performance measurements for the effect of data standardization are employed. The results suggest that networks trained on standardized data yield better results in general, but the advantage diminishes as network and sample size become large. In other words, neural networks exhibit a self-scaling capability. In addition, impact of data standardization on the performance of training algorithm in terms of computation time and number of iterations is evaluated. The results indicate that, overall, data standardization slows down training. Finally, these results are illustrated with a data set obtained from the American Telephone and Telegraph Company.
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