Now-a-days, various types of antibiotics are being used worldwide in veterinary sector indiscriminately for promotion of growth and treatment of the livestock. Significant portions of antibiotics are ...released through milk of dairy animals unaltered and exert serious harmful effects on human health. This review evaluates and compare researches on antibiotic residues in milk in published literatures from Pubmed, CrossRef, CAB direct, DOAJ, JournalTOCs, AGRICOLA, ScientificGate, Electronic Journals Library, CAB abstracts, Global Health Databases, Global Impact Factor, Google Scholar, Park Directory of Open Access Journals, BanglaJOL and ISC E-Journals. Antibiotics residue in milk was first detected in 60s and then with an increasing trend with highest after 2,000 (188). The highest no. of works, 49 (21.87%) were accomplished in China, followed by Spain, 30 (13.39%); Germany, 11 (4.91%); and USA, 10 (4.46%). Continent-wise highest researches are published from Europe, 105 (46.88%), followed by Asia, 77 (34.38%); South America, 18 (8.04%); North America, 16 (7.14%); and Africa, 8 (3.57%). For detection, Bovine milk sample is mostly used, 193 (86.16%), followed by ovine, 19 (8.48%); and caprine, 14 (6.25%). Acetonitrile was used in maximum cases (77) for processing the samples. Chromatographic technique was the highest, 115 (51.34%) for detection. Residue of ß-lactam group have been detected mostly 133 (36.54%), followed by tetracyclines, 51 (14.01%); fluoroquinolones, 49 (13.46%); sulfonamides, 46 (12.64%); and aminoglycosides, 38 (10.44%). This review observe that antibiotics residues are more common in milk samples that are being manifested in increasing researches on antibiotic detection and measures should adopt to cease this residue.
Indiscriminate and injudicious use of antibiotics in layer farms is a common practice of Bangladesh for the compensation of Poor management practices and ignorance. Despite this scenario, there is no ...published documentation on antibiotic usage pattern and farm management practices in layer farms. This study was undertaken to understand the farmers' perspective in small-scale layer farms regarding antibiotics usage and farm management.
A questionnaire survey was conducted in 120 small-scale layer farms of Mymensingh district during January-February 2017. We only considered farms in production. Data were analyzed on antibiotic usage, purpose, egg management, understanding of antibiotic residue, withdrawal period, and other issues.
Among 120 farmers, about 94.16% of farmers are using antibiotics without respecting the withdrawal period. Only 39.1% of farmers possess knowledge of residues. In our surveyed farms, 91.83% of farmers are not practicing egg washing before supplying to the market and 52.67% of farmers are unaware of cleaning and disinfection of egg tray. Ten different types of antibiotics of seven classes have found in the survey. Most antibiotics are in the Watch (49%) and Reserve (8%) groups according to the WHO AWaRe categorization and 73% antibiotics are critically important for human medicine and are considered as last resort.
This study found that due to the lack of knowledge and poor management, farmers consider using antibiotics as the most effective practices to control disease and enhancement of egg production. These indiscriminate uses of antibiotics are responsible for antibiotic residual and resistance problem. Here, we also provide some suggestion and guidelines to improve management practices to minimize the emerging problems of antimicrobial resistance through small-scale layer farms.
We report the results of a geochemical study of the Jijal and Sarangar complexes, which constitute the lower crust of the Mesozoic Kohistan paleo-island arc (Northern Pakistan). The Jijal complex is ...composed of basal peridotites topped by a gabbroic section made up of mafic garnet granulite with minor lenses of garnet hornblendite and granite, grading up-section to hornblende gabbronorite. The Sarangar complex is composed of metagabbro. The Sarangar gabbro and Jijal hornblende gabbronorite have melt-like, light rare earth element (LREE)-enriched REE patterns similar to those of island arc basalts. Together with the Jijal garnet granulite, they define negative covariations of LaN, YbN and (La/Sm)N with Eu* Eu* = 2 × EuN/(SmN + GdN), where N indicates chondrite normalized, and positive covariations of (Yb/Gd)N with Eu*. REE modeling indicates that these covariations cannot be accounted for by high-pressure crystal fractionation of hydrous primitive or derivative andesites. They are consistent with formation of the garnet granulites as plagioclase-garnet assemblages with variable trapped melt fractions via either high-pressure crystallization of primitive island arc basalts or dehydration-melting of hornblende gabbronorite, provided that the amount of segregated or restitic garnet was low (<5 wt %). Field, petrographic, geochemical and experimental evidence is more consistent with formation of the Jijal garnet granulite by dehydration-melting of Jijal hornblende gabbronorite. Similarly, the Jijal garnet-bearing hornblendite lenses were probably generated by coeval dehydration-melting of hornblendites. Melting models and geochronological data point to intrusive leucogranites in the overlying metaplutonic complex as the melts generated by dehydration-melting of the plutonic protoliths of the Jijal garnet-bearing restites. Consistent with the metamorphic evolution of the Kohistan lower arc crust, dehydration-melting occurred at the mature stage of this island arc when shallower hornblende-bearing plutonic rocks were buried to depths exceeding 25-30 km and heated to temperatures above c. 900°C. Available experimental data on dehydration-melting of amphibolitic sources imply that thickening of oceanic arcs to depths >30 km (equivalent to c. 1·0 GPa), together with the hot geotherms now postulated for lower island arc crust, should cause dehydration-melting of amphibole-bearing plutonic rocks generating dense garnet granulitic roots in island arcs. Dehydration-melting of hornblende-bearing plutonic rocks may, hence, be a common intracrustal chemical and physical differentiation process in island arcs and a natural consequence of their maturation, leading to the addition of granitic partial melts to the middle-upper arc crust and formation of dense, unstable garnet granulite roots in the lower arc crust. Addition of LREE-enriched granitic melts produced by this process to the middle-upper island arc crust may drive its basaltic composition toward that of andesite, affording a plausible solution to the 'arc paradox' of formation of andesitic continental-like crust in island arc settings.
This study delves into the properties of the associated act V over the monoid S of sinshT. It examines the relationship between faithful, finitely generated, and separated acts, as well as their ...connections to one-to-one and onto operators. Additionally, the correlation between acts over a monoid and modules over a ring is explored. Specifically, it is established that functions as an act over S if and only if functions as module, where T represents a nilpotent operator. Furthermore, it is proved that when T is onto operator and is finitely generated, is guaranteed to be finite-dimensional. Prove that for any bounded operator the following, is acting over S if and only if is a module where T is a nilpotent operator, is a faithful act over S, where T is any bounded linear operator, if T is any bounded operator, then is separated, if is separated act over S, Then T is injective, if a basis K = {vj, j} for V, then every element w of can be composed as =(pn (T) + . v, for some v in V, and put T as similar to any operator from to and V as a finite dimensional normed space, then is Noetherian act over S if S is Noetherian.
A new differential potentiometric technique based on a simple RC phase inverter circuit that can be used in a variety of automated applications for specific experimental requirements in an analytical ...laboratory.
Obese IBD patients used significantly more medications for diabetes, hypertension and hyperlipidemia and there was a trend towards increased biologic use. ...research should examine the impact of ...weight loss on reducing IBD complications and polypharmacy.Table 1. Medications Prescriptions for Pain, Hypertension, Hyperlipidemia, Diabetes, Biologics within IBD Population BMI Type Number of Patients with IBD Percent BMI Type of Total (%) Chronic Opioids Aspirin Statin ACE/ARB Metformin Biologics Underweight (< 18.5) 83 5.9 2 0 0 0 0 42 Normal (18.5-24.9) 547 41.5 3 10 18 15 5 271 Overweight (25-29.9) 431 30.5 2 20 27 22 7 167 Obese ( >30.0) 314 22.2 6 17 31 24 16 132 Total 1415 100 13 47 76 61 28 612 P value No association 0.008 0.00 0.002 0.00 0.34 Author Notes *Presenter
Unbalanced climate during the last decades has created spatially alarming and destructive situations in the world. Anomalies in temperature and precipitation enhance the risks for crop production in ...large agricultural region (especially the Southern Punjab) of Pakistan. Detailed analysis of historic weather data (1980–2011) record helped in creating baseline data to compare with model projection (SimCLIM) for regional level. Ensemble of 40 GCMs used for climatic projections with greenhouse gas (GHG) representative concentration pathways (RCP-4.5, 6.0, 8.5) was selected on the baseline comparison and used for 2025 and 2050 climate projection. Precipitation projected by ensemble and regional weather observatory at baseline showed highly unpredictable nature while both temperature extremes showed 95 % confidence level on a monthly projection. Percentage change in precipitation projected by model with RCP-4.5, RCP-6.0, and RCP-8.5 showed uncertainty 3.3 to 5.6 %, 2.9 to 5.2 %, and 3.6 to 7.9 % for 2025 and 2050, respectively. Percentage change of minimum temperature from base temperature showed that 5.1, 4.7, and 5.8 % for 2025 and 9.0, 8.1, and 12.0 % increase for projection year 2050 with RCP-4.5, 6.0, and 8.5 and maximum temperature 2.7, 2.5, and 3.0 % for 2025 and 4.7, 4.4, and 6.4 % for 2050 will be increased with RCP-4.5, 6.0, and 8.5, respectively. Uneven increase in precipitation and asymmetric increase in temperature extremes in future would also increase the risk associated with management of climatic uncertainties. Future climate projection will enable us for better risk management decisions.
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