The spinal cord, brain, optic nerves and peripheral nerves may be affected by vitamin B12 (cobalamin) deficiency. Deficiency of vitamin B12 also causes megaloblastic anaemia, meaning that the red ...blood cells are usually larger than normal. In this paper we report a 16-year old girl who was referred to us for the evaluation of mild paraparesis and paresthesias marked by tingling "pins and needles" feelings and general weakness. The patient, her parents and sisters were on a strict vegan diet, which made us believe that vitamin B12 deficiency may be the possible cause of the neurologic clinical manifestations. The serum level of vitamin B12 was low, but there was no macrocytosis in the routine blood examination. The electrophoresis of haemoglobin was pathologic, there was 3.7% of HbA2 and 11.6% of HbF (heterozygous form of beta-thalassaemia). When megaloblastic anaemia occurs in combination with a condition that gives rise to microcytic anaemia, many megaloblastic features may be masked. Instead of being macrocytic, the anaemia could be normocytic or even microcytic. Vitamin B12 deficiency is a diagnosis that must not be overlooked. This case report turns the light on the fact that increased MCV is a hallmark in vitamin B12 deficiency, but it is not an obligatory sign.
BPPV je općenito najčešći uzrok vrtoglavice, prouzročen otkidanjem sitnih kristalića kalcijeva karbonata, zvanih otokonije ili otoliti, iz otolitičke mrlje utrikulusa, najčešće zbog degenerativnih ...procesa ili traume. Djelovanjem sile teže, pri određenom položaju glave koji se podudara sa smjerom sile teže, otoliti dospijevaju u jedan od polukružnih kanalića labirinta, najčešće stražnji zbog postojećih anatomskih odnosa. Plutajući endolimfom, podražuju kupularno osjetilo, izazivajući simptome kratkotrajne, ali snažne vrtoglavice. Razlikuju se dva glavna klinička oblika BPPV-a: kanalolitijaza – nakupljanje otolita u kanalićima i kupulolitijaza – nakupljanje otolita neposredno uz sámo kupularno osjetilo. Dijagnoza bolesti postavlja se pozitivnom položavajućom probom, Dix-Hallpikeovom za stražnji polukružni kanalić, a supine roll za bočni kanalić. Premda se može očekivati spontani oporavak nakon nekoliko tjedana ili mjeseci, različiti postupci repozicije otolita dovode do trenutačnog poboljšanja, smanjenjem ili potpunim povlačenjem simptoma bolesti. Ove smjernice namijenjene su svima koji se u svojem radu mogu susresti s BPPV-om, a cilj im je pomoć u postavljanju dijagnoze i primjeni odgovarajućeg načina liječenja oboljelih.
Want to demonstrate factors which effect appearance and severity of lumbosacral radiculopathy. We analysed 100 electromyoneurographically examined patients. Patients were categorised on bases of ...their BMI (body mass index), sex, age, job type (physical or intellectual job), and chronic diseases (diabetes mellitus, arterial hypertension and hyperlipidemia). Data were evaluated using the c2 test with the significance of p<0.05. Obese patients had severe radiculopathy more often than non-obese patients (p<0.044). Severe radiculopathy appeared more frequently in male (p<0.001), elderly patients (p<0.023), and patients doing physically intensive jobs (p<0.002). No statistic significance was found in relationship between patients suffering from diabetes mellitus, arterial hypertension, and hyperlipidemia, and the severity of lumbosacral radiculopathy. Obese patients, males, elderly patients, and patients doing physically intensive jobs are at a bigger risk of suffering from severe radiculopathy. Diabetes mellitus, arterial hypertension, and hyperlipidemia do not influence the severity of lumbosacral radiculopathy.
Objective of this paper is to review drug-induced movement disorders (D-IMD) treated patients on Department of Neurology in University Hospital Osijek. We reviewed patients treated during 10 years ...period (from 1992 to 2002). Analysed group consisted of 14 patients. Reasons for hospitalisation were swallowing problems in 6 patients, neuroleptic malignant syndrome (NMS) in 3 patients, stroke in 2 patients, bolus choking in 2 patients, and speech disturbance in 1 patient.Working diagnosis for most of our patients was neurological disease, yet only later D-IMD diagnosis was established excluding primary neurological disease, or as associated disease to basic neurological disorder. Nine patients have diagnosed as Parkinson syndrome, 3 patients as NMS, and 4 as orolingual dyskinesia, either autonomously, or in combination with Parkinson syndrome. D-IMD was most frequently caused by neuroleptics. Thus the small number of patients hospitalised regarding this syndrome on Department of Neurology.
Provedeno je ispitivanje 75 bolesnika liječenih na Klinici za neurologiju i Odjelu za neurokirurgiju Kliničke bolnice Osijek kod kojih je CT pregledom potvrđena sumnja na cerebralnu hemoragiju. U ...kliničkoj slici 42 bolesnika imala su pri prijamu očevidan blaži neurološki ispad (parezu), a 31 bolesnik teški ispad (plegiju). Stanje poremećene svijesti bilo je kod 41 bolesnika. CT pregled učinjen je prosječno nakon 3,1 dana liječenja. Prosječno liječenje na Klinici za neurologiju trajalo je 19 dana. Ishod liječenja u 40 (53%) bolesnika bio je pozitivan u smislu preživljavanja, a u 22 (30%) letalan. Od 13 (17,3%) bolesnika liječenih na Odjelu neurokirurgiju 8 (10,6%) je preživjelo, a 5 (6,6%) je preminulo.
Spinal myoclonus after cervical spine extension procedure: case report Tomic, Svetlana; Cubra, Mirjana; Juric, Stjepan ...
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology,
06/2014, Letnik:
35, Številka:
6
Report
