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zadetkov: 64
21.
  • Boosting the enzymatic acti... Boosting the enzymatic activity of CxxC motif-containing PDI family members
    Kuramochi, Tsubura; Yamashita, Yukino; Arai, Kenta ... Chemical communications, 06/2024, Letnik: 6, Številka: 48
    Journal Article
    Recenzirano
    Odprti dostop

    Compounds harboring high acidity and oxidizability of thiol groups permit tuning the redox equilibrium constants of CxxC sites of members of the protein disulphide isomerase (PDI) family and thus can ...
Celotno besedilo
Dostopno za: UL
22.
  • Clinical utility of 18-fluo... Clinical utility of 18-fluorodeoxyglucose positron emission tomography/computed tomography in malignant pleural mesothelioma
    TERADA, TAKAYUKI; TABATA, CHIHARU; TABATA, RIE ... Experimental and therapeutic medicine, 08/2012, Letnik: 4, Številka: 2
    Journal Article
    Recenzirano
    Odprti dostop

    Malignant pleural mesothelioma (MPM) is an aggressive malignant tumor of mesothelial origin associated with asbestos exposure. MPM has a limited response to conventional chemotherapy and ...
Celotno besedilo
Dostopno za: UL

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23.
  • Impact of membrane curvatur... Impact of membrane curvature on amyloid aggregation
    Terakawa, Mayu S.; Lin, Yuxi; Kinoshita, Misaki ... Biochimica et biophysica acta. Biomembranes, 09/2018, Letnik: 1860, Številka: 9
    Journal Article
    Recenzirano
    Odprti dostop

    The misfolding, amyloid aggregation, and fibril formation of intrinsically disordered proteins/peptides (or amyloid proteins) have been shown to cause a number of disorders. The underlying mechanisms ...
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Dostopno za: UL

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24.
  • Semi-enzymatic acceleration... Semi-enzymatic acceleration of oxidative protein folding by N -methylated heteroaromatic thiols
    Okada, Shunsuke; Matsumoto, Yosuke; Takahashi, Rikana ... Chemical science, 07/2023, Letnik: 14, Številka: 28
    Journal Article
    Recenzirano
    Odprti dostop

    We report the first example of a synthetic thiol-based compound that promotes oxidative protein folding upon 1-equivalent loading to the disulfide bonds in the client protein to afford the native ...
Celotno besedilo
Dostopno za: UL
25.
  • Semi-enzymatic acceleration... Semi-enzymatic acceleration of oxidative protein folding by -methylated heteroaromatic thiols
    Okada, Shunsuke; Matsumoto, Yosuke; Takahashi, Rikana ... Chemical science (Cambridge), 07/2023, Letnik: 14, Številka: 28
    Journal Article
    Recenzirano

    We report the first example of a synthetic thiol-based compound that promotes oxidative protein folding upon 1-equivalent loading to the disulfide bonds in the client protein to afford the native ...
Celotno besedilo
Dostopno za: UL
26.
  • Redox-active chemical chape... Redox-active chemical chaperones exhibiting promiscuous binding promote oxidative protein folding under condensed sub-millimolar conditions
    Suzuki, Koki; Nojiri, Ryoya; Matsusaki, Motonori ... Chemical science (Cambridge), 2024
    Journal Article
    Recenzirano
    Odprti dostop

    Proteins form native structures through folding processes, many of which proceed through intramolecular hydrophobic effect, hydrogen bond and disulfide-bond formation. In vivo , protein aggregation ...
Celotno besedilo
Dostopno za: UL
27.
Celotno besedilo
Dostopno za: UL

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28.
  • A unique leucine-valine adh... A unique leucine-valine adhesive motif supports structure and function of protein disulfide isomerase P5 via dimerization
    Okumura, Masaki; Kanemura, Shingo; Matsusaki, Motonori ... Structure, 12/2021, Letnik: 29, Številka: 12
    Journal Article
    Recenzirano
    Odprti dostop

    P5, also known as PDIA6, is a PDI family member involved in the ER quality control. Here, we revealed that P5 dimerizes via a unique adhesive motif contained in the N-terminal thioredoxin-like ...
Celotno besedilo
Dostopno za: UL
29.
  • Serum HMGB1 as a prognostic... Serum HMGB1 as a prognostic marker for malignant pleural mesothelioma
    Tabata, Chiharu; Shibata, Eisuke; Tabata, Rie ... BMC cancer, 04/2013, Letnik: 13, Številka: 1
    Journal Article
    Recenzirano
    Odprti dostop

    Malignant pleural mesothelioma (MPM) is an aggressive malignant tumor of mesothelial origin that shows a limited response to conventional chemotherapy and radiotherapy. Therefore, diagnosing MPM ...
Celotno besedilo
Dostopno za: UL

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30.
  • Human ER Oxidoreductin-1α (... Human ER Oxidoreductin-1α (Ero1α) Undergoes Dual Regulation through Complementary Redox Interactions with Protein-Disulfide Isomerase
    Kanemura, Shingo; Okumura, Masaki; Yutani, Katsuhide ... Journal of biological chemistry/˜The œJournal of biological chemistry, 11/2016, Letnik: 291, Številka: 46
    Journal Article
    Recenzirano
    Odprti dostop

    In the mammalian endoplasmic reticulum, oxidoreductin-1α (Ero1α) generates protein disulfide bonds and transfers them specifically to canonical protein-disulfide isomerase (PDI) to sustain oxidative ...
Celotno besedilo
Dostopno za: UL

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zadetkov: 64

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