Highlights • We explored the possibility of using tooth crown dimensions to estimate stature. • Crown dimensions showed significant albeit low to moderate correlation with stature. • We created ...regression equations from tooth crown dimensions to estimate stature. • The applicability and reliability of regression equations were assessed. • Tooth crown dimensions cannot estimate stature with accuracy as required in forensic situations.
Two novel carbon paste electrodes based on gentamicin‐reineckate (GNS‐RN)/multiwall carbon nanotubes (MWCNTs)/sodium tetraphenyl borate (NaTPB) or potassium tetraphenylborate (KTPB) for ...potentiometric determination of gentamicin sulfate were constructed. Our endeavors of lowering the detection limit for gentamicin ion‐selective electrodes were described. The paper focused on gentamicin carbon paste electrodes based on GNS‐RN as electroactive material, o‐nitrophenyloctyl ether (o‐NPOE) as plasticizer and incorporation of MWCNTs and lipophilic anionic additives (NaTPB and KTPB) which lower the detection limit of the electrodes showing best results for determination of gentamicin ion. The characteristics of the electrodes, GNS‐RN+NaTPB+MWCNTs (sensor 1) and GNS‐RN+KTPB+ MWCNTs (sensor 2), were measured, showing favorable features as they provided measurements of the potential with near‐Nernstian slopes of 29.6±0.3 and 29.1±0.3 mV/decade over the concentration range of 1.0×10−6–1.0×10−2 mol L−1 and pH ranges 3.0–8.2 and 3.0–8.0 in short response times (6.5 sec). Importantly, the electrodes had low detection limits of 3.0×10−7and 3.4×10−7 mol L−1 for the two sensors, respectively. The sensors showed high selectivity for gentamicin ion with respect to a large number of interfering species. The electrodes were successfully applied for the potentiometric determination of GNS ions in pure state, pharmaceutical preparations and human urine with high accuracy and precision. The results of this study were compared with some previously published data using other analytical methods.
Amphotericin B is a fungicidal substance that is treatment of choice for most systemic fungal infections affecting immunocompromised patients. However, severe side effects have limited the utility of ...this drug. The aim of this study was to evaluate the antifungal effect of the combination of amphotericin B with black tea or white tea and protective of citotoxic effect. The present study shows that white and black teas have additive effects with amphotericin B against some species Candida. In addition, the combination of white and black tea with amphotericin B may reduce the toxicity of amphotericin B to red blood cells. Our results suggest that white and black tea is a potential agent to combine with amphotericin for antifungal efficacy and to reduce the amphotericin dose to lessen side effects.
Aim
This work aims to study the impact of different SUV variants in terms of mean and maximum measures as well as various normalization methods with respect to body weight, body mass index, body ...surface area, and lean body mass in patients with lymphoma.
Methods
Sixty-nine patients (34 male–35 female) were retrospectively selected. All patients had undergone F18-FDG PET/CT using the standard imaging protocol. In the first part of this study, SUVmean and SUVmax of patients’ lesions and three background sites including liver, aorta, and muscle were determined. Then, the normalization of lesion SUV to body weight and body background sites was performed. The ratio of lesion SUVmax to body background sites (muscle, aorta, and liver) SUVmax was determined in addition to the ratio of lesion SUVmean to body background sites SUVmean. The second part of the study included the calculations of the body mass index (BMI), body surface area (BSA), and lean body mass (LBM). The normalization of lesion, liver, aorta, and muscle SUV to BMI, BSA, and LBM was calculated and compared to each other.
Results
After performing the appropriate statistical calculations, the results showed that there is a significant difference in SUV measurements between the three background sites. Lesions normalized to the liver were significantly lower than those normalized to aorta and muscle and the results also showed a higher magnitude of lesions normalized to muscle in comparison to the aorta. The SUVmax and SUVmean normalized to different body weight indices showed the lowest variation with BSA and BMI while being increasingly higher with lean body mass using the two methods James and Janmahasatian, respectively, and then highest with body weight.
Conclusion
The SUVmax and SUVmean showed lower variance in comparison to other background regions. Less variation was also remarkable in SUVmean normalized to BSA and Janma lean mass and also when SUVmax is normalized to James lean body mass. The SUVmax normalized to lean (i.e., James) as well as SUVmean normalized to lean (i.e., Janma) and BSA showed a significant independence with body weight.
Background:
Axonal damage is considered a major cause of disability in multiple sclerosis (MS) and may start early in the disease. Specific biomarkers for this process are of great interest.
...Objective:
To study if cerebrospinal fluid (CSF) biomarkers for axonal damage reflect and predict disease progression already in the earliest stages of the disease, that is, in clinically isolated syndrome (CIS).
Methods:
We assessed CSF levels of neurofilament heavy (NFH), neurofilament light (NFL) and N-acetylaspartate (NAA) in 67 patients with CIS and 18 controls with neuropsychiatric diseases of non-inflammatory aetiology (NC). Patients with CIS underwent baseline magnetic resonance imaging (MRI) at 3T, and a follow-up MRI after 1 year was obtained in 28 of them.
Results:
Compared with NC, patients with CIS had higher NFH (p=0.05) and NFL (p<0.001) levels. No significant group differences were found for NAA. Patients’ NFH levels correlated with physical disability (r=0.304, p<0.05) and with change in brain volume over 1 year of follow-up (r=-0.518, p<0.01) but not with change in T2 lesion load.
Conclusion:
Our results confirm increased neurofilament levels already in CIS being related to the level of physical disability. The association of NFH levels with brain volume but not lesion volume changes supports the association of these markers with axonal damage.
Lanthanum, cerium, neodymium, and samarium were sorption from aqueous solutions using zirconium titanate (ZrTi) and polyacrylonitrile zirconium titanate (PANZrTi) ion exchangers. The ...characterizations of prepared materials were performed using XRD, SEM, FTIR, TGA, and DTA techniques. The sorption behavior of various ions toward synthesized resin has been studied depending on reaction temperatures, pH values, and initial concentrations. The selectivity order found is Sm3+ > Nd3+ > Ce3+ > La3+ on ZrTi-100, Ce3+ > Sm3+ ap Nd3+ > La3+ on ZrTi-150, and Sm3+ ap Ce3+ > Nd3+ > La3+ on PANZrTi depending on the condition of prepared ZrTi samples. The Kd for lanthanide ions was slightly decreased with temperature increased, which indicated the exothermic nature. The sorption data obtained for equilibrium conditions have been analyzed using the different isotherm models, and the applicability of these isotherm equations was compared by the correlation coefficients, R2. It was established that the equilibrium isotherm models' applicability follows the order: Langmuir > Dubinin- Radushkevich > Freundlich. It is found the Ce3+ has high adsorption capacity on each of ZrTi-100 and ZrTi-150, while Nd3+ has high adsorption capacity on PANZrTi.
In this paper, nonlinear constitutive models are proposed for steel fiber reinforced concrete (SFRC) in compression and tension. The models were implemented in the finite element computer program ...ANSYS for 3-D nonlinear analysis of SFRC corbels under monotonic static loading. Several validation studies have been performed for normal-strength and high-strength SFRC corbels with constant or variable depth. Good agreement is generally achieved between experimental and numerical results for the load-deflection curves and crack patterns. Additionally, parametric studies have been performed in order to investigate the effect of structural parameters on the performance of SFRC corbels. It was found that: (1) increasing the concrete compressive strength (fc’) improves corbel shear capacity and toughness, (2) the inclusion of steel fiber (Vf) delays premature shear failure for corbels and enhances strain ductility, (3) an enhancement in shear capacity and strain ductility is noticed by increasing the ratio of horizontal stirrups (ρh), and finally, (4) increasing the shear span-to-depth ratio (a/d) reduces the shear capacity of SFRC corbels. Corbel shear capacity increases by 27% due to a 33% increase in (fc’), by 31% due to Vf = 1% inclusion, by 20% due to a 1% increase in (ρh), and by 20% due to a 39% decrease in (a/d) ratio. The proposed nonlinear finite element approach is efficient in determining the expected enhancement in shear capacity and ductility of SFRC corbels, and consequently in optimizing design parameters for such elements.
•Validation / Parametric studies were performed on the experimentally tested SFRC corbels from the literature.•Constitutive relations for fibrous concrete are included.•The proposed numerical approach is a good tool for modelling SFRC corbels with constant or with variable depths.
3-(1,4-Dioxo-3,4,4e,5,10,10a-hexahydro-1
H-5,10-benzeno-benzogphthalazin-2-yl)-3-oxo-propiononitrile (
1) was utilized as key intermediate for the synthesis of some new iminocoumarin
2, chromenone
3, ...aminothiazole
4, triazepine
5a, b and
6, hydrazono-propiononitrile
7, pyridopyrazotriazine
8, monobromo
9, dibromo
10 quinoxaline
11, ketene
N,S-acetal
13, ketene
S,S-diacetal
17 and
18a, b and methyl dithioate
20 derivatives, respectively. The newly synthesized compounds were characterized by IR,
1H NMR,
13C NMR and mass spectral studies. Representative compounds of the synthesized product were tested and evaluated as antibacterial agent.
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The Problem
This issue of Advances addresses an important and so far largely unexplored area of practice and research: Talent management and development (TMD) in emerging market economies. Given the ...growing importance of the emerging markets, understanding how current and future talents in these countries are educated and trained is a matter of high priority for academics, business executives, and policy makers worldwide. However, systematic studies of TMD in emerging markets and especially English-language publications on this topic are scarce. We hope that this work closes an important gap in the academic literature by bridging TMD studies and research on emerging markets, and by providing analysis of TMD practices in a number of key emerging economies.
The Solution
TMD is one of the important areas of focus for human resource development (HRD) researchers and practitioners. Most research on TMD is conducted in the West, while the current state and indigenous practices of TMD in the majority of countries of the world are not explored. Articles in this special issue provided an overview of TMD in some of the emerging market economies: Asia, Eastern Europe, Middle East, Africa, and BRICS sector (Brazil, Russia, India, China, and South Africa) and cover a range of TMD practices and topics. While some authors focused more on TMD in the business sector (e.g., Brazil, Russia, and India), others discussed such topics as TMD in higher education (e.g., Vietnam), the difference between private and public institutions in TMD for managers and executives (e.g., Korea, UAE), and current practices of TMD in the public and private sectors (China). Chapters from China, South Korea, Vietnam, Russia, India, UAE, Sub-Saharan Africa, and Brazil are included in this special issue.
The Stakeholders
This issue is expected to benefit HRD researchers, HRD practitioners, and organizations by providing TMD theories, research, and practice from different cultural perspectives around the globe. In addition, practical ways of talent development and talent management for organizations are advanced in the issue.
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