The synthetic control (SC) method, a powerful tool for estimating average treatment effects (ATE), is increasingly popular in fields such as statistics, economics, political science, and marketing. ...The SC is particularly suitable for estimating ATE with a single (or a few) treated unit(s), a fixed number of control units, and large pre and post-treatment periods (which we refer as "long panels"). To date, there has been no formal inference theory for SC ATE estimator with long panels under general conditions. Existing work mostly use placebo tests for inference or some permutation methods when the post-treatment period is small. In this article, we derive the asymptotic distribution of the SC and modified synthetic control (MSC) ATE estimators using projection theory. We show that a properly designed subsampling method can be used to obtain confidence intervals and conduct inference whereas the standard bootstrap cannot. Simulations and an empirical application that examines the effect of opening a physical showroom by an e-tailer demonstrate the usefulness of the MSC method in applications.
Supplementary materials for this article are available online.
We propose a conceptual design of InSe/g-C3N4 van der Waals heterostructure to achieve highly efficient and spontaneous water splitting. InSe/g-C3N4 possesses a direct band gap of 2.04 eV with ...type-II band alignment, which is beneficial to the separation of electrons and holes and exhibits proper valence and conduction-band positions for the redox reactions of H2O. In addition, the adsorption of multiple water molecules and the changes of free energy on InSe/g-C3N4 have been calculated to understand the oxygen evolution reaction (OER) process of water splitting. The free energies of reaction on three sides are all downhill, and the values of ΔG reduce to about −0.406 eV, indicating that the OER of water splitting is a thermodynamically permissible reaction without the aid of any other substance. Therefore, the water-splitting reaction could be thermodynamically continued using InSe/g-C3N4 as a photocatalyst, which indicates that InSe/g-C3N4 is an excellent candidate for photocatalyst or photoelectronic applications.
The geometric structure of a single-particle energy band in a solid is fundamental for a wide range of many-body phenomena and is uniquely characterized by the distribution of Berry curvature over ...the Brillouin zone. We realize an atomic interferometer to measure Berry flux in momentum space, in analogy to an Aharonov-Bohm interferometer that measures magnetic flux in real space. We demonstrate the interferometer for a graphene-type hexagonal optical lattice loaded with bosonic atoms. By detecting the singular π Berry flux localized at each Dirac point, we establish the high momentum resolution of this interferometric technique. Our work forms the basis for a general framework to fully characterize topological band structures.
We present a lattice-QCD-based determination of the chiral phase transition temperature in QCD with two degenerate, massless quarks and a physical strange quark mass using lattice QCD calculations ...with the highly improved staggered quarks action. We propose and calculate two novel estimators for the chiral transition temperature for several values of the light quark masses, corresponding to Goldstone pion masses in the range of 58 MeV≲m_{π}≲163 MeV. The chiral phase transition temperature is determined by extrapolating to vanishing pion mass using universal scaling analysis. Finite-volume effects are controlled by extrapolating to the thermodynamic limit using spatial lattice extents in the range of 2.8-4.5 times the inverse of the pion mass. Continuum extrapolations are carried out by using three different values of the lattice cutoff, corresponding to lattices with temporal extents N_{τ}=6, 8, and 12. After thermodynamic, continuum, and chiral extrapolations, we find the chiral phase transition temperature T_{c}^{0}=132_{-6}^{+3} MeV.
Phase-field models, sometimes referred to as gradient damage or smeared crack models, are widely used methods for the numerical simulation of crack propagation in brittle materials. Theoretical ...results and numerical evidences show that they can predict the propagation of a pre-existing crack according to Griffith’ criterion. For a one-dimensional problem, it has been shown that they can predict nucleation upon a critical stress, provided that the regularization parameter be identified with the material’s internal or characteristic length. In this article, we draw on numerical simulations to study crack nucleation in commonly encountered geometries for which closed-form solutions are not available. We use U- and V-notches to show that the nucleation load varies smoothly from that predicted by a strength criterion to that of a toughness criterion when the strength of the stress concentration or singularity varies. We present validation and verification numerical simulations for both types of geometries. We consider the problem of an elliptic cavity in an infinite or elongated domain to show that variational phase field models properly account for structural and material size effects.
Our main claim, supported by validation and verification in a broad range of materials and geometries, is that crack nucleation can be accurately predicted by minimization of a nonlinear energy in variational phase field models, and does not require the introduction of ad-hoc criteria.
Although flow diverters have been reported with favorable clinical and angiographic outcomes in various literatures, randomized trials determining their true effectiveness and safety are still in ...lack. The Parent Artery Reconstruction for Large or Giant Cerebral Aneurysms Using the Tubridge Flow Diverter (PARAT) trial was designed to evaluate the safety and efficacy of the Tubridge flow diverter in the treatment of large or giant aneurysms in comparison with Enterprise stent-assisted coiling.
This prospective, multicenter, randomized trial was conducted at 12 hospitals throughout China. Enrolled adults with unruptured large/giant intracranial aneurysms were randomly assigned (1:1) to receive either Enterprise stent-assisted coiling or Tubridge flow diverter implantation. The primary end point was complete occlusion at 6-month follow-up, while secondary end points included technical success, mortality, target vessel-related stroke, aneurysm bleeding, in-stent stenosis, parent artery occlusion, and the frequency of all adverse events.
Among 185 enrolled subjects, 41 withdrew before procedure initiation. Overall, 82 subjects underwent Tubridge implantation, and 62 subjects were primarily treated with stent-assisted coiling. The results of 6-month follow-up imaging included complete occlusion rates of 75.34% versus 24.53% for the Tubridge and stent-assisted coiling groups, respectively, with a calculated common odds ratio of 9.4 (95% confidence interval, 4.14-21.38;
< .001). There was a higher, nonsignificant frequency of complications for Tubridge subjects. Multivariate analysis showed a decreased stroke rate at the primary investigational site, with a marginal
value (
= .051).
This trial showed an obviously higher rate of large and giant aneurysm obliteration with the Tubridge FD over Enterprise stent-assisted coiling. However, this higher obliteration rate came at the cost of a nonsignificantly higher rate of complications. Investigational site comparisons suggested that a learning curve for flow-diverter implantation should be recognized and factored into trial designs.
We search for signatures of gravitational lensing in the binary black hole events detected by Advanced LIGO and Virgo during their first two observational runs. In particular, we look for three ...effects: (1) evidence of lensing magnification in the individual signals due to galaxy lenses, (2) evidence of multiple images due to strong lensing by galaxies, and (3) evidence of wave optics effects due to point-mass lens. We find no compelling evidence of any of these signatures in the observed gravitational wave signals. However, as the sensitivities of gravitational wave detectors improve in the future, detecting lensed events may become quite likely.