Inertial confinement fusion Randewich, Andrew; Lock, Rob; Garbett, Warren ...
Philosophical transactions of the Royal Society of London. Series A: Mathematical, physical, and engineering sciences,
11/2020, Letnik:
378, Številka:
2184
Journal Article
In this study, I consider the status of the academic discipline of entrepreneurship as represented in refereed journal articles and citations in the Web of Science database within a broad ...philosophical framework, developed for this investigative purpose. This dissertation firstly explores an understanding of knowledge as offered by French social theorist, Michael Foucault, identifying two forms of knowledge. Using Foucault’s distinctions, I develop models that position savoir and connaissance knowledge, which I define as practical applications of understanding and academic orientations of explaining, in relation to disciplines and discourses. The strategic apparatus of the episteme is included in my models as a discipline-based method of determining the acceptability of knowledge into the discipline, incorporating the varied roles of gate-keepers, intellectuals and other participants into the models. The roles of epistemology and ontology are discussed and included in the models. Further, drawing on the works of German philosopher, Martin Heidegger, I introduce the concept of an ontological test as a possible means to consider whether an academic discipline clearly understands its ‘meaning of being’ or, alternatively, could be considered to have passed Foucault’s point of epistemologization and be termed a ‘dubious discipline’. Academic thinking on entrepreneurship has come under an array of criticism from within the discipline, including criticism as to a perceived lack of objectivity. The models developed in this dissertation are applied to the discipline of entrepreneurship in order to better understand the development of the discipline of entrepreneurship and the reasons for this criticism. Using the episteme of the Web of Science database, I apply citation analysis to identify those articles and texts which are considered within the entrepreneurship discipline to have the highest gravitas. These high gravitas articles are used to create an archaeological representation or aliran that illustrates the development of the discipline over time and the ontological development of sub-aliran. This aliran is a phenomenological representation of the discipline based upon the episteme to depict the episteme ‘as it is’. This representation is hermeneutically interpreted to discern the development of various sub-aliran, and identify the possible influence of gate keepers with high gravitas in such development. Based upon my survey of high gravitas articles from the aliran, I found there was a general exclusion of practitioner both as an audience for and as a source of savoir knowledge. Admittedly this finding could well be attributed to the nature of the episteme selected for the research. The exception to this general finding was in the Venture Capital sub-aliran. Further findings indicated an apparent feature of the aliran was a higher than expected level of demarcation between the organization and the firm. This demarcation had several features including an increasing trend towards learning by the organization as applied to entrepreneurship. Firms were not perceived to engage in learning but did engage in new ventures and undertook innovation. These functions were not indicated within the aliran to be part of the functions of the organization. Innovation was also not shown to be an activity conducted by individuals but was a preserve of the firm. These findings are consistent with the political structure of the Academy of Management’s Entrepreneurship Division and indicate the influence this body likely has on the discipline. In some instances, as might be expected, there was an overt level of construction of some sub-aliran by those with high gravitas in the discipline. This was most apparent in endeavours to add ‘corporate’ nominations to entrepreneurship, innovation and venturing. In the case of corporate entrepreneurship, such overt construction was perceived to be less than successful. However, the changing orientation offered by such construction is seen to offer a new direction to entrepreneurship which may be realized in the fledgling Strategic Entrepreneurship sub-aliran. Some sub-aliran observed was considered to be more introverted due to restraints imposed by the political structuring of the discipline. While the discipline of entrepreneurship may not to be able to pass Heidegger’s ontological test and could be considered a dubious discipline (doubtless like so many others), this finding should not be deemed to be unduly negative. As with Gadamer’s rehabilitation of prejudice, the term dubious could be rehabilitated to be positive and encourage moves towards greater objectivity, or at least greater rigour, within the discipline of entrepreneurship.
Dissertation (MPhil) -- AUT University, 2009.
Includes bibliographical references. Also held in print (xiv, 262 leaves ; 30 cm.) in the Archive at the City Campus (T 338.040711 LOC)
Arterio-ureteral fistula (AUF) is an uncommon diagnosis, but increasingly reported and potentially lethal. This systematic review comprehensively presents risk factors, pathophysiology, location and ...clinical presentation of AUF aiming to increase clinical awareness of this rare but life-threatening condition, and to put this entity into a contemporary perspective with modern diagnostic tools and treatment strategies.
This review was performed according to the PRISMA (Preferred Reporting Items for a Systematic Review and Meta-Analysis of Individual Participant Data) guidelines. A literature search in PubMed® and EMBASE™ was conducted. In addition, retrieved articles were cross-referenced. Data parameters included oncologic, vascular and urological history, diagnostics, treatment, and followup, and were collected using a standard template by 2 independent reviewers.
A total of 245 articles with 445 patients and 470 AUFs were included. Most patients had chronic indwelling ureteral stents (80%) and history of pelvic oncology (70%). Hematuria was observed in 99% of the patients, of whom 76% presented with massive hematuria with or without previous episodes of (micro)hematuria. For diagnosis, angiography had a sensitivity of 62%. The most predominant location of AUF was at the common iliac artery ureteral crossing. AUF-specific mortality before 2000 vs after 2000 is 19% vs 7%, coinciding with increasing use of endovascular stents.
AUF should be considered in patients with a medical history of vascular surgery, pelvic oncologic surgery, irradiation and/or chronic indwelling ureteral stents presenting with intermittent (micro)hematuria. A multidisciplinary consultation is necessary for diagnosis and treatment. The most sensitive test is angiography and the preferred initial treatment is endovascular.
Objective
To evaluate the long‐term follow‐up (primary and secondary patency) of metal stent placement in benign ureteroileal anastomotic strictures after Bricker urinary diversion and to compare the ...failed treatment group with the group of successfully treated patients to search for predisposing factors of stent failure.
Patients and Methods
For patients treated since 1989 for benign ureteroileal strictures after Bricker urinary diversion with end‐to‐side anastomosis, we retrospectively collected data on clinical history, stent placement, auxiliary measures and patency rates from a prospectively kept database.
Results
In all, 49 patients (mean age 64 years) underwent 56 metal stent procedures. Placement of the stent was possible in all patients. Stent patency without auxiliary treatment remained adequate in 23 cases (primary patency of 41.1%, mean follow‐up 37.7 months). A secondary treatment was successfully performed in 11 patients who had stent obstruction, mostly caused by hyperplastic reaction, encrustation, or migration of the stent. The secondary patency rate was 60.7% (mean follow‐up 55.8 months), comparable with patency rates of 36–100% described in literature with mostly small patient groups and much shorter follow‐up periods.
Conclusion
To the best of our knowledge we report the largest series of metal stenting in benign ureteroileal anastomotic strictures with the longest follow‐up. We show that placement of a metal stent can lead to a permanent de‐obstruction in approximately six out of 10 patients with preservation of renal function.
Purpose
Arterio-ureteral fistula (AUF) is an uncommon diagnosis, but potentially lethal. Although the number of reports has increased over the past two decades, the true incidence and contemporary ...urologists’ experience and approach in clinical practice remains unknown. This research is conducted to provide insight in the incidence of AUF in The Netherlands, and the applied diagnostic tests and therapeutic approaches in modern practice.
Methods
A nationwide cross-sectional questionnaire analysis was performed by sending a survey to all registered Dutch urologists. Data collection included information on experience with patients with AUF; and their medical history, diagnostics, treatment, and follow-up, and were captured in a standardized template by two independent reviewers. Descriptive statistics were used.
Results
Response rate was 62% and 56 AUFs in 53 patients were reported between 2003 and 2018. The estimated incidence of AUF in The Netherlands in this time period is 3.5 AUFs per year. Hematuria was observed in all patients; 9% intermittent microhematuria, and 91% presenting with, or building up to massive hematuria. For the final diagnosis, angiography was the most efficient modality, confirming diagnosis in 58%. Treatment comprised predominantly endovascular intervention.
Conclusion
The diagnosis AUF should be considered in patients with persistent intermittent or massive hematuria.