Reactions of chlorogermanes and chlorostannanes with trichlorosilane / triethylamine and reactions of germyl- and stannylphosphanes with hexachlorodisilane lead to new compounds with Ge-Si and Sn-Si ...bonds, among them unexpected novel heteroneopentanes (R
3
M)
2
Si(SiCl
3
) (M = Ge, Sn; R = alkyl). Reaction sequences leading to these highly branched trialkylgermyl- or stannyloligosilanes were followed by heteronuclear n.m.r. spectroscopy.
The shift from hypothesis-driven to data-driven science implies new methods for hypothesis generation. Creativity support has to be offered for problem finding based on research data. ...DataCreativityTools (DCT) is a research & development project building a pilot creativity support tool for the OpEN.SC biomedical data.
DaimlerChrysler Bank is one of the leading German auto-banks and for years has been expanding at a rate well above the sector average. Fast and fault-free business processes with low process costs ...are a key success factor for long-term retention of satisfied customers through new profitable financial services. A year ago, DaimlerChrysler Bank decided to implement ARIS Process Performance Manager. This article discusses the procedure and the experiences gained during the rollout of process measurement for the credit application process. It ends with a look at future uses for the tool.
Zusammenfassung
Sobald in geisteswissenschaftlichen Forschungen Daten selbst erzeugt werden, wird Forschungsdatenmanagement erforderlich. Informationsinfrastruktureinrichtungen haben auf ein ...funktionierendes Datenmanagement mit der Digitalisierung von Kulturgut großen Einfluss, und nicht immer gibt es ein abgestimmtes Rollenverständnis. Die Verständigung über divergierende Sichten bei der Datenerzeugung durch die Domänen Forschung und Infrastruktur ermöglicht erfolgreiches Datenmanagement. Ein aktiver Datenmanagementplan dokumentiert diesen Prozess.
The preparation of no-carrier-added
18F labelled NNC 12-0817 (1-(2-
bis(4-fluorophenyl)methoxyethyl)-4-4-oxo-4-(2-thienly)butylpiperazine) and NNC 12-0818 (1-(2
...bis(4-fluorophenyl)methoxyethyl)-4-4-hydroxy-4-(2-thienyl)butylpiperazine is described. NNC 12-0818 is the designation of the racemic mixture of two enantiomers. Fluorine-18 is introduced into 4-
18Ffluoro-4′-fluorobenzophenone from the corresponding triflate salt by a nucleophilic aromatic substitution reaction. A no-carrier-added synthesis was performed in 6 steps starting from N,N-dimethylaniline and 4-fluorobenzoyl chloride giving
18FNNC 12-0817 and
18FNNC 12-0818 in good yields and a radiochemical purity after HPLC-purification higher than 99%.
PDF
![Synthesis of [ 18F]NNC 12-0...](http://api.summon.serialssolutions.com/2.0.0/image/issn/XR4PS5YY4K/0969-8043/small "Synthesis of [ 18F]NNC 12-0817 and [ 18F]NNC 12-0818; two potential radioligands for the dopamine transporter")