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Trenutno NISTE avtorizirani za dostop do e-virov UL. Za polni dostop se PRIJAVITE.

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zadetkov: 90
1.
  • Spatially resolved transcri... Spatially resolved transcriptomics and its applications in cancer
    Maniatis, Silas; Petrescu, Joana; Phatnani, Hemali Current opinion in genetics & development, 02/2021, Letnik: 66
    Journal Article
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    Spatially resolved transcriptomics (SRT) offers the promise of understanding cells and their modes of dysfunction in the context of intact tissues. Technologies for SRT have advanced rapidly with a ...
Celotno besedilo
Dostopno za: UL

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2.
  • Spatiotemporal dynamics of ... Spatiotemporal dynamics of molecular pathology in amyotrophic lateral sclerosis
    Maniatis, Silas; Äijö, Tarmo; Vickovic, Sanja ... Science, 04/2019, Letnik: 364, Številka: 6435
    Journal Article
    Recenzirano
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    Paralysis occurring in amyotrophic lateral sclerosis (ALS) results from denervation of skeletal muscle as a consequence of motor neuron degeneration. Interactions between motor neurons and glia ...
Celotno besedilo
Dostopno za: NUK, ODKLJ

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3.
  • A Neurodegeneration-Specifi... A Neurodegeneration-Specific Gene-Expression Signature of Acutely Isolated Microglia from an Amyotrophic Lateral Sclerosis Mouse Model
    Chiu, Isaac M.; Morimoto, Emiko T.A.; Goodarzi, Hani ... Cell reports, 07/2013, Letnik: 4, Številka: 2
    Journal Article
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    Microglia are resident immune cells of the CNS that are activated by infection, neuronal injury, and inflammation. Here, we utilize flow cytometry and deep RNA sequencing of acutely isolated spinal ...
Celotno besedilo
Dostopno za: UL

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4.
  • An RNA-sequencing transcrip... An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex
    Zhang, Ye; Chen, Kenian; Sloan, Steven A ... The Journal of neuroscience, 2014-Sep-03, 2014-09-03, 20140903, Letnik: 34, Številka: 36
    Journal Article
    Recenzirano
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    The major cell classes of the brain differ in their developmental processes, metabolism, signaling, and function. To better understand the functions and interactions of the cell types that comprise ...
Celotno besedilo
Dostopno za: CMK, UL

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5.
  • Phosphorylation and functio... Phosphorylation and functions of the RNA polymerase II CTD
    Phatnani, Hemali P; Greenleaf, Arno L Genes & development, 2006-Nov-01, 2006-11-01, 20061101, Letnik: 20, Številka: 21
    Journal Article
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    The C-terminal repeat domain (CTD), an unusual extension appended to the C terminus of the largest subunit of RNA polymerase II, serves as a flexible binding scaffold for numerous nuclear factors; ...
Celotno besedilo
Dostopno za: UL

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6.
  • Non-cell-autonomous pathoge... Non-cell-autonomous pathogenic mechanisms in amyotrophic lateral sclerosis
    Van Harten, Alexandra C.M.; Phatnani, Hemali; Przedborski, Serge Trends in neurosciences, 08/2021, Letnik: 44, Številka: 8
    Journal Article
    Recenzirano
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    Amyotrophic lateral sclerosis (ALS) is the most common adult-onset paralytic disorder, characterized mainly by a loss of motor neurons (MNs) in the CNS. Over the past decades, thanks to intense ...
Celotno besedilo
Dostopno za: UL
7.
  • Identification of Required ... Identification of Required Host Factors for SARS-CoV-2 Infection in Human Cells
    Daniloski, Zharko; Jordan, Tristan X.; Wessels, Hans-Hermann ... Cell, 01/2021, Letnik: 184, Številka: 1
    Journal Article
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    To better understand host-virus genetic dependencies and find potential therapeutic targets for COVID-19, we performed a genome-scale CRISPR loss-of-function screen to identify host factors required ...
Celotno besedilo
Dostopno za: UL

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8.
  • CDK12 is a transcription el... CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1
    Bartkowiak, Bartlomiej; Liu, Pengda; Phatnani, Hemali P ... Genes & development, 2010-Oct-15, 2010-10-15, 20101015, Letnik: 24, Številka: 20
    Journal Article
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    Drosophila contains one (dCDK12) and humans contain two (hCDK12 and hCDK13) proteins that are the closest evolutionary relatives of yeast Ctk1, the catalytic subunit of the major elongation-phase ...
Celotno besedilo
Dostopno za: UL

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9.
  • Astrocyte pathology and the... Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy
    Serio, Andrea; Bilican, Bilada; Barmada, Sami J. ... Proceedings of the National Academy of Sciences - PNAS, 03/2013, Letnik: 110, Številka: 12
    Journal Article
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    Glial proliferation and activation are associated with disease progression in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar dementia. In this study, we describe a unique platform to ...
Celotno besedilo
Dostopno za: UL

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10.
  • An open source toolkit for ... An open source toolkit for repurposing Illumina sequencing systems as versatile fluidics and imaging platforms
    Pandit, Kunal; Petrescu, Joana; Cuevas, Miguel ... Scientific reports, 03/2022, Letnik: 12, Številka: 1
    Journal Article
    Recenzirano
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    Fluorescence microscopy is a key method in the life sciences. State of the art -omics methods combine fluorescence microscopy with complex protocols to visualize tens to thousands of features in each ...
Celotno besedilo
Dostopno za: UL
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zadetkov: 90

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