Prevalence of chronic rhinosinusitis in São Paulo DE MENDONCA PILAN, Renata Ribeiro; DE REZENDE PINNA, Fabio; PINTO BEZERRA, Thiago Freire ...
Rhinology,
06/2012, Letnik:
50, Številka:
2
Journal Article
Recenzirano
Odprti dostop
Studies designed to investigate chronic rhinosinusitis (CRS) epidemiology play an important role to assess population`s distribution and risk factors to result in the development and promotion of ...public health policies.
This study design is a survey carried out with a complex two-stage cluster sampling plan. Personal interviews were carried out with 2,003 individuals. The questionnaire included the epidemiological criteria for CRS. Demographic data, history of physician-diagnosed respiratory diseases (asthma, sinusitis, rhinitis), smoking, family income, educational attainment, and household characteristics were also evaluated.
The overall response rate was 93.9% of the households. Mean age was 39.8 +- 21 years; 45.33% were male. The overall prevalence of CRS in the city of Sao Paulo was 5.51%. We found a significant association between diagnosis of CRS and diagnosis of asthma and CRS and diagnosis of rhinitis and a significant association between presence of CRS and belonging to the low-income subgroup.
The municipality of Sao Paulo has an urban population of 11 million. According to the present study, the prevalence of CRS is 5.51%, which represents more than 500,000 individuals affected by this condition in the city.
BACKGROUND: This study aimed to assess clinical outcomes of long-term low-dose oral doxycycline therapy in difficult-to-treat chronic rhinosinusitis with polyps (CRSwNP). METHODS: This was a ...prospective, open-label study of 60 patients with difficult-to-treat CRSwNP who had undergone endoscopic sinus surgery. Patients were divided into two groups: 28 received nasal steroids, saline irrigation, and doxycycline (200 mg on the first day, followed by 100 mg once daily) for 12 weeks, while 30 received only nasal steroids and saline irrigation. The main outcome measure was an adequate effect size of doxycycline treatment on clinically meaningful significant improvement of SNOT-20. Other outcome measures were the SNOT-20, NOSE, and Lund-Kennedy scores. The following parameters were also analyzed: asthma, rhinitis, non-steroidal-exacerbated respiratory disease (NERD), and baseline serum IgG, IgA, IgE, IgM, ANCA, and eosinophil count. RESULTS: There was an adequate effect size of doxycycline treatment on clinically meaningful significant improvement of SNOT-20. Patients who received doxycycline also had significantly better outcomes regarding SNOT-20, NOSE, and Lund-Kennedy scores. There was a negative association among a clinically significant improvement of SNOT-20 and presence of asthma, NERD, and elevated serum IgE levels before treatment. CONCLUSION: These findings suggest that doxycycline may have a beneficial role for CRSwNP patients, especially for patients without asthma, NERD or high levels of serum IgE before treatment.
Tubular catalytic membranes (TMCs) active in the direct synthesis of hydrogen peroxide were prepared, characterized, and tested using methanol as the reaction medium. Low hydrogen peroxide ...selectivity was found when only palladium was used as a catalyst, whereas palladium/platinum bimetallic samples gave higher productivity and selectivity, with an optimum molar ratio of 18. The H 2 O2 decomposition rate is influenced by the feed gases. O2 improves H2 O2 stability, whereas H2 causes hydrogen peroxide to decompose at a higher rate. The most likely decomposition pathway should be the reduction of H2 O2 to water by H2 . Bromide ion was used as a promoter and when used in excess (60 ppm) causes a decrease in overall catalytic activity.
Plants from Brazilian tropical grasslands of the cerrado biome (also referred to as the Cerrado region) are characterized by the possessing of belowground bud-bearing organs that may be of stem or ...root origin that enhance the likelihood of surviving a dry season or fire. The root-derived bud bank is referred to when speaking about adventitious sprouting from roots. Root buds or root sprouts allow rapid regrowth after a disturbance or a period of adverse climatic conditions and have the potential to generate clonal populations. Adventitious sprouting from roots is well known to occur in Brazil in perennial species, mainly woody plants. In the present study, we investigate the occurrence of adventitious buds on roots of the annual species
Siphanthera arenari
a (DC.) Cogn., which is endemic to the Serra do Espinhaço range in Brazil and grows in an area of the cerrado biome. Shoots emerging from the root system of
S. arenaria
were assessed in a microscopic analysis and classified as reparative-type buds emerging from the cortical parenchyma. The presence of root buds in
Siphantera arenaria
represents the first record for the Melastomataceae family in the cerrado biome and also the first record of a root bud in an annual species for this biome.
Propolis is a complex mixture of beeswax, resinous and volatile substances produced by honeybees with material collected from plant exudates. The essential oil obtained from a propolis samples from ...southern Brazil was extracted by hydro-distillation. The yield of oil is high (8.5%), and its major constituents are the monoterpenes α-pinene (86%), β-pinene (12%) and camphene (1%). At 1% concentration, the oil inhibited the germination of lettuce seeds. At 0.25%, the growth speed index and the growth of the hypocotyl–radicle axis reduced substantially. The oil at 0.5% inhibited the elongation of procambial cells and shifted the elongation of the ground meristem cells axially to radially. Hence, the elongation zone assumed a stratified arrangement. In radicles from seeds treated with oil at 1%, a radially directed cell elongation took place in the root cap, protoderm and procambium, preventing the root to protrude. Intercellular spaces appeared between layers of cells of the ground meristem. The anatomical changes observed might be an effect of monoterpenes, either promoting the production of ethylene or affecting the sensitivity of meristem cells to this regulator.
Biogenic structures edified by crustose coralline algae (CCA) are known to enhance biodiversity, but the mechanisms involved are only partially defined. This study aims at contributing to the ...knowledge of the interaction between habitat-builder CCA and epibiont assemblages through a manipulative approach. To achieve this objective, transplantations of the CCA Lithophyllum stictiforme were performed to test the following hypotheses: 1) the structure of L. stictiforme epibiont assemblage changes between depth and biogeographic area; 2) L. stictiforme epibiont assemblage is different and more diversified than the assemblage recruited on bare rock; 3) the early L. stictiforme epibiont assemblage differ from the mature L. stictiforme epibiont assemblage. A total of 63 epibiontic taxa were found on the transplanted L. stictiforme thalli, such as 7 Chlorophyta, 10 Ochrophyta, 40 Rhodophyta, 1 Sarcomastigophora, 1 Porifera, 4 Bryozoa. The sessile assemblage recruited on transplanted L. stictiforme thalli depended on sites and depths, and it had a higher taxa richness compared to that colonizing the bare rock. The early recruited assemblage on L. stictiforme transplanted thalli compared to the mature assemblage on untouched thalli was different mostly in the relative abundance of taxa, rather than in species composition. These manipulative experiments highlighted for the first time the role of a common CCA on the development and biodiversity of coralligenous assemblages, contributing to emphasize the importance of CCA conservation efforts.
•Lithophyllum stictiforme thalli were transplanted at different depths and sites.•The interaction between crustose coralline algae and epibionts was investigated.•The assemblages had a higher diversity on transplanted thalli than on bare rock.
In this study synthesis and characterization of solid acid catalysts with definite textural properties (high surface area, narrow pore size dimension, ordered structure) are described. In particular ...sulphated zirconia (SZ) has been introduced on three ordered mesoporous silica, MCM-41, MCM-48 and SBA-15, in order to study the influence of silica supports on textural and chemical–physical properties of final catalysts. The correlation between the catalytic behavior of SZ supported samples and their textural and chemical physical properties was studied in the liquid-phase acylation of anisole with benzoic anhydride.
Optical properties of thin Cu
2
ZnSnS
4
films produced by RF magnetron sputtering of preliminarily synthesized material are studied. Transmission and reflection coefficients are studied in a range ...from 0.4 to 26 μm. The optical band-gap width depending on substrate temperature is estimated; in optimal modes, it is equal to 1.47 eV. The study of electrical properties shows that Cu
2
ZnSnS
4
possesses low charge-carrier mobility, μ = 1.9 cm
2
/(V s), at room temperature and hole concentration
р
= 5 × 10
18
cm
–3
. Electron microscopy shows that the film possesses a polycrystalline structure with a crystallite size on the order of 100 nm.
•Measurement of 20Ne + 130Te double charge exchange reaction.•Nuclear reactions induced by heavy-ion accelerated beams as tools towards the determination of the double beta decay nuclear matrix ...elements.•NUMEN (NUclear Matrix Elements for Neutrinoless double beta decay) project at INFN – LNS.•Heavy-ion induced reactions with the MAGNEX magnetic spectrometer.
The 130Te(20Ne,20O)130Xe double charge exchange reaction was measured for the first time at very forward angles with the MAGNEX magnetic spectrometer at INFN-LNS. The study, performed at beam energy of 306 MeV, is part of a systematic exploration promoted by the NUMEN project. The last aims to measure specific reaction cross sections to provide experimentally driven information about nuclear matrix elements of interest in the context of neutrinoless double beta decay.
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