Background
Timeliness of care is an important dimension of health care quality. The determining factors of less timely care and their influence on the survival of patients with lung cancer (LC) ...remain uncertain.
Aims
To analyse the delays in the diagnosis and treatment of LC in our health area, the factors associated with the timeliness of care and their possible relationship with the survival of these patients.
Methods
A retrospective study was conducted on all patients with a cytohistologically confirmed diagnosis of LC between 1 June 2005 and 31 May 2008. The time delays for consultation (specialist delay), diagnosis (diagnosis delay), and treatment (treatment delay), were analysed, as well as the factors associated with these delays and the influence of the timeliness of care on survival.
Results
A total of 307 cases were included (87 % males). The mean specialist delay was 53.6 days (median 35 days), diagnosis delay 31.5 days (median 18 days), treatment delay 23.5 days (median 14 days). The greater age of the patient and a more advanced stage were associated with a shorter specialist delay. Male sex, a more advanced stage, and poor general status were associated with a shorter treatment delay. The survival is longer in patients with a longer treatment delay.
Conclusions
The delay in the diagnosis in our population seems to be excessively long. The greater the age, a more advanced tumour stage, male sex, and poor general health status are associated with shorter delays. A longer treatment delay is associated with a longer survival.
We present a comprehensive study of
B
0
→
ω
ω
decays using
772
×
10
6
B
B
¯
pairs collected with the Belle detector at the KEKB
e
+
e
−
collider. This process is a suppressed charmless decay into ...two vector mesons and can exhibit interesting polarization and
C
P
violation. The decay is observed for the first time with a significance of 7.9 standard deviations. We measure a branching fraction
B
=
(
1.53
±
0.29
±
0.17
)
×
10
−
6
, a fraction of longitudinal polarization
f
L
=
0.87
±
0.13
±
0.13
, and a time-integrated
C
P
asymmetry
A
C
P
=
−
0.44
±
0.43
±
0.11
, where the first uncertainties listed are statistical and the second are systematic. This is the first observation of
B
0
→
ω
ω
and the first measurements of
f
L
and
A
C
P
for this decay.
<supplementary-material>
<copyright-statement>Published by the American Physical Society</copyright-statement>
2024
</supplementary-material>
We report the results of the first search for
B
−
decays to the
Ξ
¯
c
0
Λ
¯
c
−
final state using
711
fb
−
1
of data collected at the
ϒ
(
4
S
)
resonance with the Belle detector at the KEKB ...asymmetric-energy
e
+
e
−
collider. The results are interpreted in terms of both direct baryon-number-violating
B
−
decay and
Ξ
c
0
−
Ξ
¯
c
0
oscillations which follow the standard model decay
B
−
→
Ξ
c
0
Λ
¯
c
−
. We observe no evidence for baryon number violation and set the 95% confidence-level upper limits on the ratio of baryon-number-violating and standard model branching fractions
B
(
B
−
→
Ξ
¯
c
0
Λ
¯
c
−
)
/
B
(
B
−
→
Ξ
c
0
Λ
¯
c
−
)
to be
<
2.7
%
and on the effective angular frequency of mixing
ω
in
Ξ
c
0
−
Ξ
¯
c
0
oscillations to be
<
0.76
ps
−
1
(equivalent to
τ
mix
>
1.3
ps
).
<supplementary-material>
<copyright-statement>Published by the American Physical Society</copyright-statement>
2024
</supplementary-material>
First measurement of the Λc+→ pη′ decay Li, S. X.; Shen, C. P.; Adachi, I. ...
The journal of high energy physics,
03/2022, Letnik:
2022, Številka:
3
Journal Article
Recenzirano
Odprti dostop
A
bstract
We present the first measurement of the branching fraction of the singly Cabibbo-suppressed (SCS) decay
Λ
c
+
→ pη
′ with
η
′
→ ηπ
+
π
−
, using a data sample corresponding to an integrated ...luminosity of 981 fb
−
1
, collected by the Belle detector at the KEKB
e
+
e
−
asymmetric-energy collider. A significant
Λ
c
+
→ pη
′ signal is observed for the first time with a signal significance of 5.4
σ
. The relative branching fraction with respect to the normalization mode
Λ
c
+
→ pK
−
π
+
is measured to be
B
Λ
c
+
→
pη
′
B
Λ
c
+
→
pK
−
π
+
=
7.54
±
1.32
±
0.73
×
10
−
3
,
where the uncertainties are statistical and systematic, respectively. Using the world-average value of
B
Λ
c
+
→
pK
−
π
+
= (6
.
28
±
0
.
32)
×
10
−
2
, we obtain
B
Λ
c
+
→
pη
′
=
4.73
±
0.82
±
0.46
±
0.24
×
10
−
4
,
where the uncertainties are statistical, systematic, and from
B
Λ
c
+
→
pK
−
π
+
, respectively.
The first simultaneous determination of the absolute value of the Cabibbo-Kobayashi-Maskawa matrix element $V_{ub}$ using inclusive and exclusive decays is performed with the full Belle data set at ...the $\Upsilon(4S)$ resonance, corresponding to an integrated luminosity of 711 fb^{-1}$. We analyze collision events in which one $B$ meson is fully reconstructed in hadronic modes. This allows for the reconstruction of the hadronic $X_u$ system of the semileptonic $b \to u \ell \bar \nu_\ell$ decay. We separate exclusive $B \to \pi \, \ell\, \bar \nu_{\ell}$ decays from other inclusive $B \to X_u \, \ell\, \bar \nu_{\ell}$ and backgrounds with a two-dimensional fit, that utilizes the number of charged pions in the $X_u$ system and the four-momentum transfer $q^2$ between the $B$ and $X_u$ system. Combining our measurement with information from lattice QCD and QCD calculations of the inclusive partial rate as well as external experimental information on the shape of the $B \to \pi \, \ell\, \bar \nu_{\ell}$ form factor, we determine $\left|V_{ub}^{\mathrm{excl.}} \right| = (3.78 \pm 0.23 \pm 0.16 \pm 0.14)\times 10^{-3}$ and $\left|V_{ub}^{\mathrm{incl.}} \right| = (3.88 \pm 0.20 \pm 0.31 \pm 0.09)\times 10^{-3}$, respectively, with the uncertainties being the statistical error, systematic errors, and theory errors. The ratio of $\left|V_{ub}^{\mathrm{excl.}} \right| / \left|V_{ub}^{\mathrm{incl.}} \right| = 0.97 \pm 0.12$ is compatible with unity.
A
bstract
We measure the cross section of
e
+
e
−
→
η
c
J/ψ
at the Υ(
nS
)(
n
= 1–5) on-resonance and 10.52 GeV off-resonance energy points using the full data sample collected by the Belle detector ...with an integrated luminosity of 955 fb
−
1
. We also search for double charmonium production in
e
+
e
−
→
η
c
J/ψ
via initial state radiation near the
η
c
J/ψ
threshold. No evident signal of the double charmonium state is found, but evidence for the
e
+
e
−
→ η
c
J/ψ
process is found with a statistical significance greater than 3
.
3
σ
near the
η
c
J/ψ
threshold. The average cross section near the threshold is measured and upper limits of cross sections are set for other regions.
We studied the impact of 13-valent pneumococcal conjugate vaccine (PCV13) on the incidence of invasive pneumococcal disease (IPD) and serotype distribution in a region with intermediate levels of ...vaccination (around 64% in children aged <2 years).
Surveillance data on IPD cases reported by microbiologists participating in the Microbiological Reporting System of Catalonia during 2006–2014 were analysed. We compared estimated incidence rate (IR) ratios for serotypes included in PCV7, PCV10non7, PCV13non10 and non-PCV13 between the PCV7 (2006–2009) and PCV13 periods (2010–2014). IR were corrected for missing serotypes according to year and age groups: <2 years, 2–4 years, 5–64 years and ≥65 years.
A total of 9338 IPD cases were reported. Overall IPD incidence declined by 26.2% (from 16.4 to 12.1) in the PCV13 period. The largest decrease was observed in children aged 2–4 years (44.5%, from 37.4 to 20.8). Pneumonia fell in all age groups with the largest reduction in children aged 2–4 years (49.3%) and <2 years (42%). PCV13 serotypes decreased significantly in all age groups, from 52% (31.6 to 15.1) in children aged 2–4 years to 35% (22.8 to 14.8) in adults aged ≥65 years. Non-PCV13 serotypes rose by 13% (14.8 to 16.8) in people aged ≥65 years.
In a region with intermediate vaccination coverage, the introduction of PCV13 has reduced the overall incidence of IPD, mainly due to the decrease in PCV13 serotypes in all age groups, suggesting herd immunity. Non-PCV13 serotypes have increased in adults aged ≥65 years, suggesting serotype replacement. Higher PCV13 vaccination coverage in children will further reduce IPD incidence in all age groups.
A
bstract
We present a search for the lepton-flavor-violating decays
B
s
0
→
ℓ
∓
τ
±
, where
ℓ
=
e, μ
, using the full data sample of 121 fb
−
1
collected at the Υ(5
S
) resonance with the Belle ...detector at the KEKB asymmetric-energy
e
+
e
−
collider. We use
B
s
0
B
¯
s
0
events in which one
B
s
0
meson is reconstructed in a semileptonic decay mode and the other in the signal mode. We find no evidence for
B
s
0
→ ℓ
∓
τ
±
decays and set upper limits on their branching fractions at 90% confidence level as
B
(
B
s
0
→ e
∓
τ
±
)
<
14
×
10
−
4
and
B
(
B
s
0
→ μ
∓
τ
±
)
<
7
.
3
×
10
−
4
. Our result represents the first upper limit on the
B
s
0
→ e
∓
τ
±
decay rate.
We study B+ → π+π0π0 using 711 fb-1 of data collected at the Υ(4S) resonance with the Belle detector at the KEKB asymmetric-energy e+e- collider. Here we measure an inclusive branching fraction of ...(19.0 ±1.5 ±1.4)×10-6 and an inclusive CP asymmetry of (9.2 ±6.8 ±0.7)%, where the first uncertainties are statistical and the second are systematic, and a B+ → ρ(770)+π0 branching fraction of (11.2 ± 1.1 ± 0.9 $^{+0.8}_{-1.6}$)× 10-6, where the third uncertainty is due to possible interference with B+ → ρ(1450)+π0. We present the first observation of a structure around 1 GeV/c2 in the π0π0 mass spectrum, with a significance of 6.4σ, and measure a branching fraction to be (6.9 ±0.9 ±0.6) × 10-6. We also report a measurement of local CP asymmetry in this structure.
