Xanthogranulomatous inflammation of the female genital tract is a rare entity. When the gynecological organs are affected, it is particularly unusual for xanthogranulomataus inflammation to involve ...only the ovary.
A 45-year-old woman with an intrauterine device, long-term exposure to nicotine, and hyperlipidemia presented with an adnexal mass and bowel obstruction. She underwent 2 exploratory laparotomies, ureteral stent placement, left salpingooophorectomy, and rectosigmoid resection with end colostomy. Pathology revealed xanthogranulomatous oophoritis without involvement of the associated fallopian tube.
The synergistic effects of intrauterine device use, abnormal lipid levels, and long-term nicotine exposure may have contributed to the development of this patient's condition. Knowledge of xanthogranulomatous inflammation is essential to avoid misdiagnosis of malignancy and excessive surgical intervention.
Micro-Abstract The goal of the present study was to examine the risk factors and outcomes of 136 patients with aggressive non-Hodgkin lymphoma treated with dose-adjusted etoposide, prednisone, ...vincristine, cyclophosphamide, and doxorubicin. Current smoking was a significant predictor of death, progression, or relapse at 2 years, and dose adjustment by hematopoietic nadir was neither positively nor negatively associated.