A classical nova occurs when material accreting onto the surface of a white dwarf in a close binary system ignites in a thermonuclear runaway. Complex structures observed in the ejecta at late stages ...could result from interactions with the companion during the common-envelope phase. Alternatively, the explosion could be intrinsically bipolar, resulting from a localized ignition on the surface of the white dwarf or as a consequence of rotational distortion. Studying the structure of novae during the earliest phases is challenging because of the high spatial resolution needed to measure their small sizes. Here we report near-infrared interferometric measurements of the angular size of Nova Delphini 2013, starting one day after the explosion and continuing with extensive time coverage during the first 43 days. Changes in the apparent expansion rate can be explained by an explosion model consisting of an optically thick core surrounded by a diffuse envelope. The optical depth of the ejected material changes as it expands. We detect an ellipticity in the light distribution, suggesting a prolate or bipolar structure that develops as early as the second day. Combining the angular expansion rate with radial velocity measurements, we derive a geometric distance to the nova of 4.54 ± 0.59 kiloparsecs from the Sun.
Rapid rotation is a fundamental characteristic of classical Be stars and a crucial property allowing for the formation of their circumstellar disks. Past evolution in a mass and angular momentum ...transferring binary system offers a plausible solution to how Be stars attained their fast rotation. Although the subdwarf remnants of mass donors in such systems should exist in abundance, only a few have been confirmed due to tight observational constraints. An indirect method of detecting otherwise hidden companions is offered by their effect on the outer parts of Be star disks, which are expected to be disrupted or truncated. In the context of the infrared and radio continuum excess radiation originating in the disk, the disk truncation can be revealed by a turndown in the spectral energy distribution due to reduced radio flux levels. In this work, we search for signs of spectral turndown in a sample of 57 classical Be stars with radio data, which include new data for 23 stars and the longest-wavelength detections so far (λ 10 cm) for two stars. We confidently detect the turndown for all 26 stars with sufficient data coverage (20 of which are not known to have close binary companions). For the remaining 31 stars, the data are inconclusive as to whether the turndown is present or not. The analysis suggests that many if not all Be stars have close companions influencing their outer disks. If confirmed to be subdwarf companions, the mass transfer spin-up scenario might explain the existence of the vast majority of classical Be stars.
Background
R0 resection rates (complete tumour removal with negative resection margins) in pancreatic cancer are 70–80 per cent when a 0‐mm margin is used, declining to 15–24 per cent with a 1‐mm ...margin. This review evaluated the R0 resection rates according to different margin definitions and techniques.
Methods
Three databases (MEDLINE from 1946, PubMed from 1946 and Embase from 1949) were searched to mid‐October 2014. The search terms included ‘pancreatectomy OR pancreaticoduodenectomy’ and ‘margin’. A meta‐analysis was performed with studies in three groups: group 1, axial slicing technique (minimum 1‐mm margin); group 2, other slicing techniques (minimum 1‐mm margin); and group 3, studies with minimum 0‐mm margin.
Results
The R0 rates were 29 (95 per cent c.i. 26 to 32) per cent in group 1 (8 studies; 882 patients) and 49 (47 to 52) per cent in group 2 (6 studies; 1568 patients). The combined R0 rate (groups 1 and 2) was 41 (40 to 43) per cent. The R0 rate in group 3 (7 studies; 1926 patients) with a 0‐mm margin was 72 (70 to 74) per cent The survival hazard ratios (R1 resection/R0 resection) revealed a reduction in the risk of death of at least 22 per cent in group 1, 12 per cent in group 2 and 23 per cent in group 3 with an R0 compared with an R1 resection. Local recurrence occurred more frequently with an R1 resection in most studies.
Conclusion
Margin clearance definitions affect R0 resection rates in pancreatic cancer surgery. This review collates individual studies providing an estimate of achievable R0 rates, creating a benchmark for future trials.
Margin clearance definitions affect radical resection rates
The Interstellar Mapping and Acceleration Probe (IMAP) is a revolutionary mission that simultaneously investigates two of the most important overarching issues in Heliophysics today: the acceleration ...of energetic particles and interaction of the solar wind with the local interstellar medium. While seemingly disparate, these are intimately coupled because particles accelerated in the inner heliosphere play critical roles in the outer heliospheric interaction. Selected by NASA in 2018, IMAP is planned to launch in 2024. The IMAP spacecraft is a simple sun-pointed spinner in orbit about the Sun-Earth L1 point. IMAP's ten instruments provide a complete and synergistic set of observations to simultaneously dissect the particle injection and acceleration processes at 1 AU while remotely probing the global heliospheric interaction and its response to particle populations generated by these processes. In situ at 1 AU, IMAP provides detailed observations of solar wind electrons and ions; suprathermal, pickup, and energetic ions; and the interplanetary magnetic field. For the outer heliosphere interaction, IMAP provides advanced global observations of the remote plasma and energetic ions over a broad energy range via energetic neutral atom imaging, and precise observations of interstellar neutral atoms penetrating the heliosphere. Complementary observations of interstellar dust and the ultraviolet glow of interstellar neutrals further deepen the physical understanding from IMAP. IMAP also continuously broadcasts vital real-time space weather observations. Finally, IMAP engages the broader Heliophysics community through a variety of innovative opportunities. This papersummarizes the IMAP mission at the start of Phase A development.
Abstract The epidemiology of invasive Haemophilus influenzae infections was evaluated in Ontario between 1989 and 2007 to assess the impact of the introduction of the conjugate H. influenzae serotype ...b (Hib) vaccine in the early 1990s on Hib and non-Hib serotypes in both vaccinated and unvaccinated cohorts as well as the possibility of “strain replacement” with non-vaccine H. influenzae strains. Data were collected by the provincial Public Health Laboratories-Toronto, Ontario Agency for Health Protection and Promotion, which performed almost all serotyping on invasive (blood, CSF, other sterile sites) H. influenzae strains isolated in the province during the study period. Temporal trends for Hib, other typeable strains, and non-typeable H. influenzae were evaluated by Poisson regression, controlling for the specimen submissions. Prior to infant Hib vaccination, the most commonly observed serotype was serotype b (64.9%). Subsequently, 70.3%, 13.6%, and 9.4% of isolates were non-typeable, serotype f, and serotype b, respectively. Infant Hib vaccination resulted in a decrease in Hib incidence in all age groups (pooled IRR 0.432) and marked increases of non-typeable and serotype f H. influenzae in children aged <5 years (IRR 2.4 and 3.0, respectively). Vaccination against Hib has altered the epidemiology of invasive H. influenzae infections in Ontario. Prevention of invasive Hib disease was observed in both vaccinated and unvaccinated age groups. Invasive H. influenzae infection now commonly presents as sepsis due to non-typeable H. influenzae in older individuals. However, strain replacement of Hib with serotype f and non-typeable strains in children under 5 years was documented.
Trapped electrons in Earth's outer Van Allen radiation belt are influenced profoundly by solar phenomena such as high-speed solar wind streams, coronal mass ejections (CME), and interplanetary (IP) ...shocks. In particular, strong IP shocks compress the magnetosphere suddenly and result in rapid energization of electrons within minutes. It is believed that the electric fields induced by the rapid change in the geomagnetic field are responsible for the energization. During the latter part of March 2015, a CME impact led to the most powerful geomagnetic storm (minimum Dst = −223 nT at 17 March, 23 UT) observed not only during the Van Allen Probe era but also the entire preceding decade. Magnetospheric response in the outer radiation belt eventually resulted in elevated levels of energized electrons. The CME itself was preceded by a strong IP shock whose immediate effects vis-a-vis electron energization were observed by sensors on board the Van Allen Probes. The comprehensive and high-quality data from the Van Allen Probes enable the determination of the location of the electron injection, timescales, and spectral aspects of the energized electrons. The observations clearly show that ultrarelativistic electrons with energies E greater than 6 MeV were injected deep into the magnetosphere at L approximately equals 3 within about 2 min of the shock impact. However, electrons in the energy range of approximately equals 250 keV to approximately equals 900 keV showed no immediate response to the IP shock. Electric and magnetic fields resulting from the shock-driven compression complete the comprehensive set of observations that provide a full description of the near-instantaneous electron energization.
Abstract
The long-period, highly eccentric Wolf-Rayet star binary system WR 140 has exceptionally well-determined orbital and stellar parameters. Bright, variable X-ray emission is generated in ...shocks produced by the collision of the winds of the WC7pd+O5.5fc component stars. We discuss the variations in the context of the colliding-wind model using broadband spectrometry from the RXTE, Swift, and NICER observatories obtained over 20 yr and nearly 1000 observations through three consecutive 7.94 yr orbits, including three periastron passages. The X-ray luminosity varies as expected with the inverse of the stellar separation over most of the orbit; departures near periastron are produced when cooling shifts to excess optical emission in C
iii
λ
5696 in particular. We use X-ray absorption to estimate mass-loss rates for both stars and to constrain the system morphology. The absorption maximum coincides closely with the inferior conjunction of the WC star and provides evidence of the ion-reflection mechanism that underlies the formation of collisionless shocks governed by magnetic fields probably generated by the Weibel instability. Comparisons with
K
-band emission and He
i
λ
10830 absorption show that both are correlated after periastron with the asymmetric X-ray absorption. Dust appears within a few days of periastron, suggesting formation within shocked gas near the stagnation point. The X-ray flares seen in
η
Car have not occurred in WR 140, suggesting the absence of large-scale wind inhomogeneities. Relatively constant soft emission revealed during the X-ray minimum is probably not from recombining plasma entrained in outflowing shocked gas.
The present study compared eight breeds of cattle differing in gender (heifers, buls and steers) to determine associations between muscle characteristics and meat sensory qualities of theLongissimus ...thoracis muscle. Animal types differed in al the muscle characteristics and sensory qualities. Many correlations among muscle characteristics and among sensory qualities were consistent for most animal types. Isocitrate dehydrogenase (ICDH) activities alowed discrimination of muscles with respect to myosin heavy chain (MyHC)-I proportions for al animal types. Lactate dehydrogenase (LDH) and phos-phofructokinase (PFK) activities were positively correlated for most animal types. Overal liking was correlated with beef lfavour and abnormal lfavour in al animal types and with global tenderness for al animal types except for Charolais cross breed steers. For al animal types except for Angus×Friesian heifers, beef lfavour and abnormal lfavour were negatively correlated. Overal liking was not correlated with juiciness. PFK, ICDH and citrate synthase (CS) activities were strongly associated with tenderness, beef lfavour and overal liking when average values for al animal types were used. However, associations between muscle characteristics and sensory qualities within animal types were weak and inconsistent.
In a joint NRL/Manila Observatory mission, as part of the Seven SouthEast Asian Studies program (7-SEAS), a 2-week, late September 2011 research cruise in the northern Palawan archipelago was ...undertaken to observe the nature of southwest monsoonal aerosol particles in the South China Sea/East Sea (SCS/ES) and Sulu Sea region. Previous analyses suggested this region as a receptor for biomass burning from Borneo and Sumatra for boundary layer air entering the monsoonal trough. Anthropogenic pollution and biofuel emissions are also ubiquitous, as is heavy shipping traffic. Here, we provide an overview of the regional environment during the cruise, a time series of key aerosol and meteorological parameters, and their interrelationships. Overall, this cruise provides a narrative of the processes that control regional aerosol loadings and their possible feedbacks with clouds and precipitation. While 2011 was a moderate El Nino-Southern Oscillation (ENSO) La Nina year, higher burning activity and lower precipitation was more typical of neutral conditions. The large-scale aerosol environment was modulated by the Madden-Julian Oscillation (MJO) and its associated tropical cyclone (TC) activity in a manner consistent with the conceptual analysis performed by Reid et al. (2012). Advancement of the MJO from phase 3 to 6 with accompanying cyclogenesis during the cruise period strengthened flow patterns in the SCS/ES that modulated aerosol life cycle. TC inflow arms of significant convection sometimes span from Sumatra to Luzon, resulting in very low particle concentrations (minimum condensation nuclei CN < 150 cm-3, non-sea-salt PM2.5 < 1 mu g m-3). However, elevated carbon monoxide levels were occasionally observed suggesting passage of polluted air masses whose aerosol particles had been rained out. Conversely, two drier periods occurred with higher aerosol particle concentrations originating from Borneo and Southern Sumatra (CN > 3000 cm-3 and non-sea-salt PM2.5 10-25 mu g m-3). These cases corresponded with two different mechanisms of convection suppression: lower free-tropospheric dry-air intrusion from the Indian Ocean, and large-scale TC-induced subsidence. Veering vertical wind shear also resulted in aerosol transport into this region being mainly in the marine boundary layer (MBL), although lower free troposphere transport was possible on the western sides of Sumatra and Borneo. At the hourly time scale, particle concentrations were observed to be modulated by integer factors through convection and associated cold pools. Geostationary satellite observations suggest that convection often takes the form of squall lines, which are bowed up to 500 km across the monsoonal flow and 50 km wide. These squall lines, initiated by cold pools from large thunderstorms and likely sustained by a veering vertical wind shear and aforementioned mid-troposphere dry layers, propagated over 1500 km across the entirety of the SCS/ES, effectively cutting large swaths of MBL aerosol particles out of the region. Our conclusion is that while large-scale flow patterns are very important in modulating convection, and hence in allowing long-range transport of smoke and pollution, more short-lived phenomena can modulate cloud condensation nuclei (CCN) concentrations in the region, resulting in pockets of clean and polluted MBL air. This will no doubt complicate large scale comparisons of aerosol-cloud interaction.
Eta Carinae is a massive interacting binary system shrouded in a complex circumstellar environment whose evolution is the source of the long-term brightening observed during the last 80 years. An ...occulter, acting as a natural coronagraph, impacts observations from our perspective, but not from most other directions. Other sight-lines are visible to us through studies of the Homunculus reflection nebula. The coronagraph appears to be vanishing, decreasing the extinction towards the central star, and causing the star's secular brightening. In contrast, the Homunculus remains at an almost constant brightness. The coronagraph primarily suppresses the stellar continuum, to a lesser extent the wind lines, and not the circumstellar emission lines. This explains why the absolute values of equivalent widths (EWs) of the emission lines in our direct view are larger than those seen in reflected by the Homunculus, why the direct view absolute EWs are decreasing with time, and why lower-excitation spectral wind lines formed at larger radii (e.g Fe ii 4585A) decrease in intensity at a faster pace than higher excitation lines that form closer to the star (e.g. Hdelta). Our main result is that the star, despite its 10-fold brightening over two decades, is relatively stable. A vanishing coronagraph that can explain both the large flux evolution and the much weaker spectral evolution. This is contrary to suggestions that the long-term variability is intrinsic to the primary star that is still recovering from the Great Eruption with a decreasing mass-loss rate and a polar wind that is evolving at a slower pace than at the equator.