Multimorbidity, according to the World Health Organization, exists when there are two or more chronic conditions in one patient. This definition seems inaccurate for the holistic approach to Family ...Medicine (FM) and long-term care. To avoid this pitfall the European General Practitioners Research Network (EGPRN) designed a comprehensive definition of multimorbidity using a systematic literature review.
To translate that English definition into European languages and to validate the semantic, conceptual and cultural homogeneity of the translations for further research.
Forward translation of the EGPRN's definition of multimorbidity followed by a Delphi consensus procedure assessment, a backward translation and a cultural check with all teams to ensure the homogeneity of the translations in their national context. Consensus was defined as 70% of the scores being higher than 6. Delphi rounds were repeated in each country until a consensus was reached.
229 European medical expert FPs participated in the study. Ten consensual translations of the EGPRN comprehensive definition of multimorbidity were achieved.
A comprehensive definition of multimorbidity is now available in English and ten European languages for further collaborative research in FM and long-term care.
Specificity of Chromatographic Adsorbents LeRosen, A. L; Monaghan, P. H; Rivet, C. A ...
Analytical chemistry (Washington),
05/1951, Letnik:
23, Številka:
5
Journal Article
ABSTRACT We introduce a novel technique to mitigate the adverse effects of atmospheric turbulence on astronomical imaging. Utilizing a video-to-image neural network trained on simulated data, our ...method processes a sliding sequence of short-exposure (∼0.2 s) stellar field images to reconstruct an image devoid of both turbulence and noise. We demonstrate the method with simulated and observed stellar fields, and show that the brief exposure sequence allows the network to accurately associate speckles to their originating stars and effectively disentangle light from adjacent sources across a range of seeing conditions, all while preserving flux to a lower signal-to-noise ratio than an average stack. This approach results in a marked improvement in angular resolution without compromising the astrometric stability of the final image.
...all the groups were polled on how likely the changes in OR attire guidelines were to affect the morale of surgeons, nurses, anesthesiologists, and the whole team. A new statement was issued in ...2018 that confirms many of the attitudes expressed by respondents to our survey.4 It states that guidelines should be created collaboratively with nursing, surgery, anesthesia, and infection control represented; that total ear and hair coverage is not supported by evidence; that skull caps are acceptable attire; and that all further issues regarding surgical attire need further evaluation. The Society for Hospital Epidemiology of, Association for Practitioners in Infection Control, Centers for Disease Control, and Surgical Infection Society.
We piloted the combined effectiveness of point-of-care viral load monitoring plus motivational enhanced adherence counseling (intervention) compared with routine care (control) in women identified at ...risk of virologic failure in the PROMOTE study in Zimbabwe. In an unblinded randomized study, consenting women with last viral load ≥200 copies/ml and/or pill count outside 90–110% range were randomized 1 : 1 to receive the intervention or continue routine care, comprising laboratory-based VL monitoring and standard EAC, from trained nurses and counsellors. Viral load was measured 0, 3, 6, and 12 months after enrolment. We compared viral suppression <200 copies/ml at 6 and 12 months between the arms through Fisher’s exact test and sought associated factors by logistic regression with a 95% confidence interval (CI). Between December 2018 and July 2019, 50 women were enrolled (25 intervention and 25 controls) and followed until November 2020. At entry, 60% of the women were virally suppressed, 52% intervention vs. 68% control arm. Viral suppression was balanced between the two arms (p value = 0.248). At month 6 post study entry (primary endpont), 64% of the women retained in care were virally suppressed, 54% intervention vs. 76% control arm (p value = 0.124). At month12 post study entry (secondary endpoint), 69% of the women retained in care were virally suppressed, 67% intervention vs. 71% control arm women (p value = 0.739). More intervention women completed all scheduled sessions by month 6. Control group women were more likely to be virally suppressed at both timepoints. Only 25% had treatment switch by 12 months. Despite intense adherence support and viral load monitoring, sustained viral suppression remained elusive in women identified at risk of viral failure. These findings highlight the continued need for effective adherence intervention for women with unsuppressed HIV viral loads, efficient treatment switch strategies, as well as drug level monitoring.
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