Over the past few decades, the life expectancy of humankind has increased significantly due to advancements in life sciences and medical research, particularly given our increasing success in the ...epidemiological and pharmacological management of bacterial, fungi, and viral infections ....
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With the expected explosive growth of the number of mobile user devices and data traffic in the next decade and beyond, and the expected development of various new applications and services such as ...vehicle-to-everything, extended reality and smart city, the requirements for Quality of Service (such as ultra-high data transmission rate, ultra-low latency, support for the highest moving speed and seamless connection, etc.) will reach levels never seen before. The sixth generation (6G) of networks is conceived to address the requirements mentioned above. Digital Twin refers to a digital representation to represent a physical entity in virtual space, while its corresponding physical object remains in the physical space. In this article, we first briefly introduce some basic knowledge of Digital Twins. We then outline possible innovative technologies expected in 6G networks that will help Digital Twin systems to reach full potential, and deliver the high-level performance needed for the next generation of communications.
Additive manufacturing has revolutionized the manufacturing paradigm in recent years due to the possibility of creating complex shaped three-dimensional parts which can be difficult or impossible to ...obtain by conventional manufacturing processes. Among the different additive manufacturing techniques, wire and arc additive manufacturing (WAAM) is suitable to produce large metallic parts owing to the high deposition rates achieved, which are significantly larger than powder-bed techniques, for example. The interest in WAAM is steadily increasing, and consequently, significant research efforts are underway. This review paper aims to provide an overview of the most significant achievements in WAAM, highlighting process developments and variants to control the microstructure, mechanical properties, and defect generation in the as-built parts; the most relevant engineering materials used; the main deposition strategies adopted to minimize residual stresses and the effect of post-processing heat treatments to improve the mechanical properties of the parts. An important aspect that still hinders this technology is certification and nondestructive testing of the parts, and this is discussed. Finally, a general perspective of future advancements is presented.
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Representation learning is making inroads into drug discovery. A study in Nature Communications emphasizes multiple limitations in property prediction. The results suggest that continued research and ...improvements are required for this specific area that coalesces machine learning and molecular medicine.Machine learning is a powerful tool for the study and design of molecules. Here the authors comment a recent publication in Nature Communications which highlights the challenges of different molecular representations for data-driven property predictions.
Ultracold-Wire and arc additive manufacturing (UC-WAAM) Rodrigues, Tiago A.; Duarte, Valdemar R.; Miranda, R.M. ...
Journal of materials processing technology,
October 2021, 2021-10-00, 20211001, Letnik:
296
Journal Article
Recenzirano
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•A novel WAAM variant, Ultracold-wire and arc additive manufacturing (UC-WAAM), was developed.•In UC-WAAM the electric arc is established between a non-consumable tungsten electrode ...and the wire feedstock.•Decreased thermal impact on the UC-WAAM-based parts, without loss of productivity.•High strength and ductility of the as-built parts were preserved.•An overhang structure was successfully produced with UC-WAAM.
This study presents a new variant of Wire and Arc Additive Manufacturing named Ultracold-Wire and Arc Additive Manufacturing (UC-WAAM), in which the electric arc is established between the wire feedstock material and a non-consumable tungsten electrode. A feasibility study was performed on HSLA steel. A comparison with conventional Gas Metal Arc Welding-based WAAM was performed. By removing the electric current through the substrate and distancing the electric arc from the molten pool, this new WAAM variant can reduce the process temperatures and increase cooling rates, without compromising the integrity or deposition rate of the as-built parts. Mechanical testing showed the preservation of the high mechanical strength and ductility of the HSLA steel parts built with UC-WAAM. Lastly, one of the unique features of this new variant is also presented: the use of a non-conductive/non-metallic block to produce overhang structures, highlighting the potential for UC-WAAM to be used to fabricate supportless complex-shaped 3D structures.
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