Adequate zinc nutrition is essential for adequate growth, immunocompetence and neurobehavioral development, but limited information on population zinc status hinders the expansion of interventions to ...control zinc deficiency. The present analyses were conducted to: (1) estimate the country-specific prevalence of inadequate zinc intake; and (2) investigate relationships between country-specific estimated prevalence of dietary zinc inadequacy and dietary patterns and stunting prevalence.
National food balance sheet data were obtained from the Food and Agriculture Organization of the United Nations. Country-specific estimated prevalence of inadequate zinc intake were calculated based on the estimated absorbable zinc content of the national food supply, International Zinc Nutrition Consultative Group estimated physiological requirements for absorbed zinc, and demographic data obtained from United Nations estimates. Stunting data were obtained from a recent systematic analysis based on World Health Organization growth standards. An estimated 17.3% of the world's population is at risk of inadequate zinc intake. Country-specific estimated prevalence of inadequate zinc intake was negatively correlated with the total energy and zinc contents of the national food supply and the percent of zinc obtained from animal source foods, and positively correlated with the phytate: zinc molar ratio of the food supply. The estimated prevalence of inadequate zinc intake was correlated with the prevalence of stunting (low height-for-age) in children under five years of age (r = 0.48, P<0.001).
These results, which indicate that inadequate dietary zinc intake may be fairly common, particularly in Sub-Saharan Africa and South Asia, allow inter-country comparisons regarding the relative likelihood of zinc deficiency as a public health problem. Data from these analyses should be used to determine the need for direct biochemical and dietary assessments of population zinc status, as part of nationally representative nutritional surveys targeting countries estimated to be at high risk.
Multilevel modeling allows researchers to understand whether relationships between lower-level variables (e.g., individual job satisfaction and individual performance, firm capabilities and ...performance) change as a function of higher-order moderator variables (e.g., leadership climate, market-based conditions). We describe how to estimate such cross-level interaction effects and distill the technical literature for a general readership of management researchers, including a description of the multilevel model building process and an illustration of analyses and results with a data set grounded in substantive theory. In addition, we provide 10 specific best-practice recommendations regarding persistent and important challenges that researchers face before and after data collection to improve the accuracy of substantive conclusions involving cross-level interaction effects. Our recommendations provide guidance on how to define the cross-level interaction effect, compute statistical power and make research design decisions, test hypotheses with various types of moderator variables (e.g., continuous, categorical), rescale (i.e., center) predictors, graph the cross-level interaction effect, interpret interactions given the symmetrical nature of such effects, test multiple cross-level interaction hypotheses, test cross-level interactions involving more than two levels of nesting, compute effect-size estimates and interpret the practical importance of a cross-level interaction effect, and report results regarding the multilevel model building process.
In the Western world, gender has traditionally been viewed as binary and as following directly from biological sex. This view is slowly changing among both experts and the general public, a change ...that has been met with strong opposition. In this article, we explore the psychological processes underlying these dynamics. Drawing on previous work on gender performativity as well as gender as a performance, we develop a psychological framework of the perpetuation and disruption of the gender/sex binary on a stage that facilitates and foregrounds binary gender/sex performance. Whenever character, costume, and script are not aligned the gender/sex binary is disrupted and gender trouble ensues. We integrate various strands of the psychological literature into this framework and explain the processes underlying these reactions. We propose that gender trouble can elicit threat—personal threat, group-based and identity threat, and system threat—which in turn leads to efforts to alleviate this threat through the reinforcement of the gender/sex binary. Our framework challenges the way psychologists have traditionally treated gender/sex in theory and empirical work and proposes new avenues and implications for future research.
The presence of outliers, which are data points that deviate markedly from others, is one of the most enduring and pervasive methodological challenges in organizational science research. We provide ...evidence that different ways of defining, identifying, and handling outliers alter substantive research conclusions. Then, we report results of a literature review of 46 methodological sources (i.e., journal articles, book chapters, and books) addressing the topic of outliers, as well as 232 organizational science journal articles mentioning issues about outliers. Our literature review uncovered (a) 14 unique and mutually exclusive outlier definitions, 39 outlier identification techniques, and 20 different ways of handling outliers; (b) inconsistencies in how outliers are defined, identified, and handled in various methodological sources; and (c) confusion and lack of transparency in how outliers are addressed by substantive researchers. We offer guidelines, including decision-making trees, that researchers can follow to define, identify, and handle error, interesting, and influential (i.e., model fit and prediction) outliers. Although our emphasis is on regression, structural equation modeling, and multilevel modeling, our general framework forms the basis for a research agenda regarding outliers in the context of other data-analytic approaches. Our recommendations can be used by authors as well as journal editors and reviewers to improve the consistency and transparency of practices regarding the treatment of outliers in organizational science research.
Over the past decade, the Database of Genomic Variants (DGV; http://dgv.tcag.ca/) has provided a publicly accessible, comprehensive curated catalogue of structural variation (SV) found in the genomes ...of control individuals from worldwide populations. Here, we describe updates and new features, which have expanded the utility of DGV for both the basic research and clinical diagnostic communities. The current version of DGV consists of 55 published studies, comprising >2.5 million entries identified in >22,300 genomes. Studies included in DGV are selected from the accessioned data sets in the archival SV databases dbVar (NCBI) and DGVa (EBI), and then further curated for accuracy and validity. The core visualization tool (gbrowse) has been upgraded with additional functions to facilitate data analysis and comparison, and a new query tool has been developed to provide flexible and interactive access to the data. The content from DGV is regularly incorporated into other large-scale genome reference databases and represents a standard data resource for new product and database development, in particular for copy number variation testing in clinical labs. The accurate cataloguing of variants in DGV will continue to enable medical genetics and genome sequencing research.
Comprises 34 essays from leading scholars in history, classics, philosophy, and political science to illuminate Greek and Roman political thought in all its diversity and depth.Offers a broad survey ...of ancient political thought from Archaic Greece through Late AntiquityApproaches ancient political philosophy from both a normative and historical focusExamines Greek and Roman political thought within historical context and contemporary debateExplores the role of ancient political thought in a range of philosophies, such as the individual and community, human rights, religion, and cosmopolitanism
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