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zadetkov: 175
1.
  • In situ detection and genot... In situ detection and genotyping of individual mRNA molecules
    Larsson, Chatarina; Söderberg, Ola; Grundberg, Ida ... Nature methods, 05/2010, Letnik: 7, Številka: 5
    Journal Article
    Recenzirano

    Increasing knowledge about the heterogeneity of mRNA expression within cell populations highlights the need to study transcripts at the level of single cells. We present a method for detection and ...
Celotno besedilo
Dostopno za: UL
2.
  • Purification of DNA oligonu... Purification of DNA oligonucleotides to improve hybridization chain reaction performance
    Leino, Mattias; Söderberg, Ola New biotechnology, 09/2023, Letnik: 76
    Journal Article
    Recenzirano
    Odprti dostop

    Hybridization Chain Reaction (HCR) is a technique to generate a linear polymerization of oligonucleotide hairpins, used in multiple molecular biology methods. The HCR reaction is dependent on every ...
Celotno besedilo
Dostopno za: UL
3.
  • Direct observation of indiv... Direct observation of individual endogenous protein complexes in situ by proximity ligation
    Söderberg, Ola; Gullberg, Mats; Jarvius, Malin ... Nature methods, 12/2006, Letnik: 3, Številka: 12
    Journal Article
    Recenzirano

    Cellular processes can only be understood as the dynamic interplay of molecules. There is a need for techniques to monitor interactions of endogenous proteins directly in individual cells and tissues ...
Celotno besedilo
Dostopno za: UL
4.
  • Activated EGFR and PDGFR in... Activated EGFR and PDGFR internalize in separate vesicles and downstream AKT and ERK1/2 signaling are differentially impacted by cholesterol depletion
    Wåhlén, Erik; Olsson, Frida; Raykova, Doroteya ... Biochemical and biophysical research communications, 07/2023, Letnik: 665
    Journal Article
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    The interplay between membrane subregions and receptor tyrosine kinases (RTK) will influence signaling in both normal and pathological RTK conditions. In this study, epidermal growth factor receptor ...
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Dostopno za: UL
5.
  • Differential impact of lipi... Differential impact of lipid raft depletion on platelet-derived growth factor (PDGF)-induced ERK1/2 MAP-kinase, SRC and AKT signaling
    Wåhlén, Erik; Olsson, Frida; Söderberg, Ola ... Cellular signalling, 08/2022, Letnik: 96
    Journal Article
    Recenzirano
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    It has become clear that lipid rafts functions as signaling hotspots connecting cell surface receptors to intracellular signaling pathways. However, the exact involvement of lipid rafts in receptor ...
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Dostopno za: UL
6.
  • Cellular responses to silen... Cellular responses to silencing of PDIA3 (protein disulphide-isomerase A3): Effects on proliferation, migration, and genes in control of active vitamin D
    Kermpatsou, Despoina; Olsson, Frida; Wåhlén, Erik ... The Journal of steroid biochemistry and molecular biology, 06/2024, Letnik: 240
    Journal Article
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    The active form of vitamin D, 1,25-dihydroxyvitamin D3, is known to act via VDR (vitamin D receptor), affecting several physiological processes. In addition, PDIA3 (protein disulphide-isomerase A3) ...
Celotno besedilo
Dostopno za: UL
7.
  • Flash-comet: Significantly ... Flash-comet: Significantly improved speed and sensitivity of the comet assay through the introduction of lithium-based solutions and a more gentle lysis
    Bivehed, Erik; Söderberg, Ola; Hellman, Björn Mutation research, 10/2020, Letnik: 858-860
    Journal Article
    Recenzirano
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    •Introducing a new protocol Flash-comet assay, with improved sensitivity and speed.•Low conductivity solution based on LiOH instead of NaOH-based solution.•Changing from lysis at pH 10 to 8.5 lowers ...
Celotno besedilo
Dostopno za: UL

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8.
  • Visualizing DNA single- and... Visualizing DNA single- and double-strand breaks in the Flash comet assay by DNA polymerase-assisted end-labelling
    Bivehed, Erik; Hellman, Björn; Wenson, Leonie ... Nucleic acids research, 02/2024, Letnik: 52, Številka: 4
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    Abstract In the comet assay, tails are formed after single-cell gel electrophoresis if the cells have been exposed to genotoxic agents. These tails include a mixture of both DNA single-strand breaks ...
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Dostopno za: UL
9.
  • Crosstalk between Hippo and... Crosstalk between Hippo and TGFβ: Subcellular Localization of YAP/TAZ/Smad Complexes
    Grannas, Karin; Arngården, Linda; Lönn, Peter ... Journal of molecular biology, 10/2015, Letnik: 427, Številka: 21
    Journal Article
    Recenzirano

    The Hippo pathway plays a crucial role in growth control, proliferation and tumor suppression. Activity of the signaling pathway is associated with cell density sensing and tissue organization. ...
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Dostopno za: UL
10.
  • Large-scale phage-based scr... Large-scale phage-based screening reveals extensive pan-viral mimicry of host short linear motifs
    Mihalič, Filip; Simonetti, Leandro; Giudice, Girolamo ... Nature communications, 04/2023, Letnik: 14, Številka: 1
    Journal Article
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    Viruses mimic host short linear motifs (SLiMs) to hijack and deregulate cellular functions. Studies of motif-mediated interactions therefore provide insight into virus-host dependencies, and reveal ...
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Dostopno za: UL
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zadetkov: 175

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