In the rapidly evolving field of business process management, there is a growing need for analytical tools that can transform complex data into actionable insights. This research introduces a novel ...approach by integrating Large Language Models (LLMs), such as ChatGPT, into process mining tools, making process analytics more accessible to a wider audience. The study aims to investigate how ChatGPT enhances analytical capabilities, improves user experience, increases accessibility, and optimizes the architectural frameworks of process mining tools. The key innovation of this research lies in developing a tailored prompt engineering strategy for each process mining submodule, ensuring that the AI-generated outputs are accurate and relevant to the context. The integration architecture follows an Extract, Transform, Load (ETL) process, which includes various process mining engine modules and utilizes zero-shot and optimized prompt engineering techniques. ChatGPT is connected via APIs and receives structured outputs from the process mining modules, enabling conversational interactions. To validate the effectiveness of this approach, the researchers used data from 17 companies that employ BehfaLab's Process Mining Tool. The results showed significant improvements in user experience, with an expert panel rating 72% of the results as "Good". This research contributes to the advancement of business process analysis methodologies by combining process mining with artificial intelligence. Future research directions include further optimization of prompt engineering, exploration of integration with other AI technologies, and assessment of scalability across various business environments. This study paves the way for continuous innovation at the intersection of process mining and artificial intelligence, promising to revolutionize the way businesses analyze and optimize their processes.
The prevalence of peptic ulcer disease in hemodialysis dependent patients is higher than the general population. These patients are also more prone to upper gastrointestinal bleeding. The aim of this ...study was to compare the effects of a standard triple therapy with a sequential therapy on Helicobacter pylori eradication in azotemic and hemodialysis patients.
Forty nine hemodialysis and azotemic patients, naïve to H. pylori treatment, were randomized into two groups to receive either standard triple therapy (pantoprazole 40 mg, amoxicillin 500 mg and clarithromycin 250 mg twice a day for 14 days) or a sequential therapy (pantoprazole 40 mg for 10 days, amoxicillin 500 mg twice a day for the first 5 days and clarithromycin 250 mg + tinidazole 500 mg twice a day just during the second 5 days). H. pylori eradication was evaluated by fecal H. pylori antigen assessment 8 weeks after the treatment.
Of 49 patients, 45 patients (21 in triple therapy group and 24 in the sequential group) completed the study. Based on intention to treat analysis, H. pylori eradication rates were 66.7% (95% confidence interval CI: 47.8-85.5%) in standard triple therapy group and 84% (95% CI: 69.6-98.3%) in sequential therapy group (P = 0.34). Per-protocol (PP) eradication rates were (95% CI: 76.2%. 6-89.3%) 54 and 87.5% (95% CI: 68.8-95.5%), respectively (P = 0.32).
According to Maastricht III consensus report, the results of our study showed that sequential therapy might be a better choice compared with the standard triple therapy in azotemic and hemodialysis patients Iran. We propose to assess the effects of shorter-duration sequential therapy (less than 10 days) for H. pylori eradication.
Design science has recently been considered as a research methodology that differs methodologically and philosophically from conventional methodologies. This methodology goes beyond ...descriptive-explanative researches and takes steps to solve problems. Though this methodology uses the research qualitative and quantitative instruments in the process of data-gathering and data-analyzing, the aim of the research is not to provide a mere description or explanation of problems or phenomena but to solve a social-technical problem through designing an artefact, model, procedure, and so on. Despite the importance of this methodology in areas such as management, information technology management, policy-making, and some other areas in social science, little attention has been given to it in Iran. That is why, lacking a solution-oriented attitude, almost all the published research papers in the field of social science concentrates on the description or explanation of problems or phenomena. In this article, while introducing and analyzing design science as a research methodology, exploring its philosophical foundations, and presenting the common frameworks in this field, we will examine its application in Iran
Objective Botulism is the acute, descending, flaccid paralysis that results when the neurotoxin of Clostridium botulinum blocks neuromuscular transmission. C botulinum toxin is the most poisonous ...substance that blocks neuromuscular transmission and causes death through airway and respiratory muscle paralysis; all forms of botulism manifest neurologically as asymmetric, descending, flaccid paralysis beginning with the cranial nerve musculature. Food-borne botulism results from the ingestion of food in which C botulinum has multiplied and produced its toxin. Patient We report a new case of food-borne botulism in a 7 year old boy with recurrent episodes of weakness, difficulty in swallowing and speech; bilateral ptosis and mydriasis. He had positive history of the same symptoms, documented twice before. The patient's samples were sent for detection of toxin of Clostridium botulinum, and toxin of C. botulinum, type A was found in his stool sample, confirming our diagnosis. This case was unusual report because our patient has not history of canned food ingestion and also because recurrent episodes of paralysis in this case are unusual findings in botulism. Conclusion In this report we want to emphasize that canned-food ingestion is not necessary for diagnosis of food-borne botulism and because delayed treatment leads to increase mortality and morbidity, treatment should be initiated promptly on the basis of clinical suspicion.
Aim. Regional analgesia has been introduced as better analgesic technique compared to using systemic analgesic agents, and it may decrease the adverse effects of them and increase the degree of ...satisfaction. Several additives have been suggested to enhance analgesic effect of local anesthetic agents such as opioids and steroids. We designed this randomized double-blind controlled study to compare the analgesic efficacy of the dexamethasone and fentanyl added to lidocaine using axillary block in patients undergoing operation of forearm fracture. Materials and Methods. Seventy-eight patients 20-60 years old were recruited in a prospective, double-blinded, randomized way. Axillary block was performed in the three groups by using 40 mL lidocaine and 2 mL distilled water (L group), 40 mL lidocaine and 2 mL dexamethasone (LD group), and 40 mL lidocaine and 2 mL fentanyl (LF group). The onset time of sensory and motor block, duration of sensory and motor block, the total analgesic dose administered during 6 hours after the surgery, and hemodynamic variables were recorded. Results. The duration of sensory and motor block was significantly longer in LD group compared to other groups (P < 0.001). Similarly, the total analgesic consumption in LD group was smaller compared to other groups (P < 0.001). Comparison of hemodynamic consequences of axillary block and surgery failed to reveal any statistically significant differences between all groups. Conclusion. Addition of dexamethasone to lidocaine significantly prolonged the duration of analgesia compared with fentanyl/lidocaine mixture or lidocaine alone using axillary block in patients undergoing forearm fracture surgery. This trial is registered with IRCT2012120711687N1. 25 references
Fire usually causes changes in the composition and diversity of herbaceous species. The present paper aimed to study the effect of repeated fire incidents on understory species diversity in the ...Saravan forests of Guilan Province located in the north of Iran. To do so, three 50-hectare areas with identical physiographical conditions and overstory (hand-planted softwood Pinus taeda) were selected. Seven fire incidences occurred for the 10-year period in one of the areas and the other area experienced three fire incidents within the same period. The area with no fire incidents was considered as the control area. All the fire incidents were surface ones. The systematic random method with a sample size 100 × 200 m was used for collecting data. Based on the above, 25 samples were determined in each area. The whole coverage of the understory was taken into consideration using Whittaker’s method and the Domain criterion so as to calculate species diversity indices. The results showed that Shannon-Wiener diversity and Menhinick’s richness in the regions which experienced 3 and 7 fire incidents were maximum and minimum, respectively, whereas no significant difference was seen between the regions with regard to Smith and Wilson’s evenness index.
Background & Aim: This study aimed to assess the relationships between iron and copper levels in maternal and cord serums together and with pregnancy outcomes. Methods & Materials: An ...Analytical cross-sectional study was conducted among 370 pregnant women in labor and their neonates in Maryam, Akbarabadi and Imam hospitals in Tehran, Iran. Copper concentrations were measured using the standard atomic absorption spectrophotometer method and Iron concentrations were measured by a kit through RA 1000 method. Data were collected using a questionnaire and were analyzed using Spearman correlation, Chi- square and Logistic regression tests. Results: The mean copper concentrations in the maternal and cord bloods at delivery were 114.52±37.4, 22.4±11.6 (μg/dl), respectively. The Iron levels were 119.2±64, 164.3±65.3 (μg/dl), respectively. Of all the mothers, 54.3% had copper deficiency, 1.1% Iron deficiency and of all the newborns, 44.7% had copper deficiency and 3.5% Iron deficiency. The Spearman Correlation analysis showed significant positive correlations between concentrations of each element in maternal serum with cord serum and also between maternal iron with maternal copper, and maternal iron with cord copper. The Chi-square analysis showed that there was a significant relationship between maternal copper deficiency and gestational hypertension (P<0.001). There were no significant relationships between these trace element levels at delivery with premature rupture of membranes and preterm labor. Logistic regression analysis showed a significant negative relationship between maternal copper levels and gestational hypertension (odds: 0.98, 95%CI: 0.97-0.99). Conclusion: Maternal copper deficiency was rather high in the participants of the study (54.3%), and was related to incidence of gestational hypertension. These findings illustrated importance of trace elements during pregnancy. Providing suitable dietary recommendations and giving supplements during pregnancy can help to decrease maternal and fetal mortality and morbidity.
In the framework of wave packet analysis, finite wavelet systems are particular classes of finite wave packet systems. In this paper, using a scaling matrix on a permuted version of the discrete ...Fourier transform (DFT) of system generator, we derive a locally-scaled version of the DFT of system genarator and obtain a finite equal-norm Parseval wavelet frame over prime fields. We also give a characterization of all multiplicative subgroups of the cyclic multiplicative group, for which the associated wavelet systems form frames. Finally, we present some concrete examples as applications of our results.
In this article, we present a constructive method for computing the frame coefficients of finite wavelet frames over prime fields using tools from computational harmonic analysis and group theory.
Introduction: Recent studies on biomechanical properties of brain tissue have focused on computer simulation of this tissue during impacts, simulation of neurosurgical procedures, and improvements in ...navigational systems for image guided surgery. Several models have been proposed to explain the mechanical behavior of brain tissue in different conditions (dynamic, static and quasi-static), but the role of the ventricles and intra-ventricular pressure has not been studied so much, especially under static loading. It is clear that the ability of biomechanical models to predict the displacement of midline structures secondary to epidural hematoma could effectively improve the accuracy of intra-operative navigational systems. In addition, simulation of midline shift can help us to understand the mechanisms involved in pathogenesis of these conditions. Plain strain computer modeling based on finite element methods has been used to study the degree of displacement and deformation of the ventricles in acute epidural hematoma to determine the more important factors in achieving a more accurate model.
Materials and Methods: A patient with an acute epidural hematoma was used to produce a plain strain elastic model of brain tissue. The model was based on the CT data. The displacement of reference points in the modeled ventricle with changing intra-ventricular pressure gradients was compared with the displacement of similar points in the real ventricle as calculated from the CT scan, and the pressure gradients that resulted in the minimum error were determined.
Results: Our data showed that best results were achieved when the pressure gradient was 1.25 KPa (9.4 mm Hg). Also, the ventricle ipsilateral to the hematoma was predicted to be compressed from both the medial and lateral walls.
Conclusion: In the plain strain biomechanical modeling of the brain in unilateral strain loading (conditions similar to those used in image guided systems), the intra-ventricular pressure gradients should be considered in order to achieve accurate results. In addition, the so-called "strain shadow effect" is emphasized.
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