Zn1–x Mn x O nanostructures were synthesized via the microwave-assisted hydrothermal method, which rapidly produces particles of controlled size and morphology. Samples were analyzed considering the ...effects of manganese ion concentration. XRD revealed that all samples had wurtzite-type structure with Mn2+ ions incorporated in the oxide lattice. UV–vis spectra showed absorption bands from the d–d transitions of Mn2+ ions. As the doping concentration increased, the value of the energy gap decreased, indicating intermediary energy levels within the band gap in the Mn-doped ZnO samples. All samples produced broad-band photoluminescence (PL) emissions in the yellow–orange–red range. Additionally, the PL intensity decreased with Mn2+ ion incorporation into the ZnO lattice due to the creation of new recombination centers. Microscopy images showed that manganese in the ZnO matrix produced homogeneously distributed nanostructures. EPR results indicated two locations of Mn2+ ions in the ZnO lattice, lower concentrations in the core of the lattice and higher concentrations at the surface.
All habitats have noise, but anthropogenic sounds often differ from natural sounds in terms of frequency, duration and intensity, and therefore may disrupt animal vocal communication. This study ...aimed to investigate whether vocalizations emitted by black-tufted marmosets (
) were affected by the noise produced by mining activity. Through passive acoustic monitoring, we compared the noise levels and acoustic parameters of the contact calls of marmosets living in two study areas (with two sampling points within each area)-one near and one far from an opencast mine in Brazil. The near area had higher anthropogenic background noise levels and the marmosets showed greater calling activity compared to the far area. Calls in the near area had significantly lower minimum, maximum and peak frequencies and higher average power density and bandwidth than those in the far area. Our results indicate that the mining noise affected marmoset vocal communication and may be causing the animals to adjust their acoustic communication patterns to increase the efficiency of signal propagation. Given that vocalizations are an important part of social interactions in this species, concerns arise about the potential negative impact of mining noise on marmosets exposed to this human activity.
Chloroquine (CQ) and hydroxychloroquine, are promising anti-inflammatory drugs for the treatment of Diabetes mellitus (DM) to prevent associated complications. Therefore, this study evaluated the ...anti-inflammatory effects of CQ-free and CQ-incorporated polylactic acid nanoparticles (NPs) in the peripheral blood mononuclear cells (PBMCs) of patients with type 1 Diabetes mellitus (T1DM). In total, 25 normoglycemic individuals and 25 patients with T1DM aged 10-16 years were selected and glycemic controls evaluated. After cell viability assessed by MTT assay, T1DM PBMCs were subjected to a CQ concentration of 10 µM in three different conditions: not treated (NT), treated with CQ, and treated with CQ NPs. The cells were incubated for 48 h, and the mRNA expressions of cytokines IL1B, IFNG, TNFA, IL12, and IL10 were determined by relative quantification through real-time PCR at 24 h intervals. IL1B expression decreased in CQ and CQ NP-treated cells after 48 h (p < 0.001) and 24 h (p < 0.05) of treatment, respectively. IFNG and IL12 expressions significantly decreased (p < 0.001) in cells treated with CQ and CQ NPs at 24 and 48 h compared to NT. TNFA and IL10 expressions significantly decreased after 48 h (p < 0.001) and 24 h (p < 0.002), respectively, by both CQ and CQ NPs treatment. Despite being a preliminary in vitro study, CQ has anti-inflammatory activity in the primary cells of T1DM patients and could represent an alternative and adjuvant anti-inflammatory therapy to prevent diabetes complications.
Black Theater, Black Performance Silva (Kabilaewatala), Renata de Lima; Peixoto, Jordana Dolores
Revista Brasileira de Estudos da Presença,
10/2022, Letnik:
12, Številka:
4
Journal Article
Odprti dostop
This article discusses the concept of Black Performance, which, associated with the Black Movement, consists of a set of expressive manifestations, from ritual to spectacle, which scenically organize ...modes of existing and resisting of the black people in the African diaspora. The methodological design consists in an approach from macro to micro elements, starting with a general definition of Black Movement, then questioning the concept of Black Performance as a category that can encompass both traditional ritualistic performances and artistic performances in the languages of theater, dance and performing art. Finally, Black Theater is considered as the focus of analysis based on its historical aspects.
Aim
The present study aimed to characterize the omission of nursing care according to the nurses' perception, the professional practice environment and the nursing workload of intensive care units ...(ICU) in Brazil. Additionally, the influence of the practice environment and nursing workload on such omission was assessed, as well as the type of care omitted regarding priority classification.
Background
In order to ensure patient safety and quality of care, it is necessary to invest in improvements in nursing care practices.
Method
The present cross‐sectional study was performed in three large ICU in Brazil. The omission of nursing care was identified using the MISSCARE‐BRASIL instrument, and the environment and duration of professional nursing practice were analysed using the Practice Environment Scale (PES) and Nursing Activities Score (NAS), respectively.
Results
“Ambulation three times a day or as prescribed” was the form of care reported as the most omitted in the three studied units. The reasons for not performing care included the following: inadequate number of staff, inadequate physical blueprint of the unit/sector and the professional having more than one employment relationship. Upon characterizing the work environment in the ICU according to the PES, ICU 1 and 3 were considered “mixed” environments, whereas ICU 2 was considered a “favourable” environment.
Conclusion
The professional practice environment, as well as the workload, may constitute predictive factors for the omission of care.
Implications for Nursing Management
The nursing workload and practice environment influence the omission of care. Moreover, the establishment of criteria for the prioritization of care when faced with adverse work conditions is necessary.
Carbon dots (CDs) exhibit luminescence, biocompatibility, and higher water solubility. This material has been developed for biological applications, specifically in bioimaging. In this work, the ...gelatin carbon dots (CDg) was obtained from commercial gelatin using a hydrothermal method in domestic microwave, and the suppression fluorescent mechanism were enhanced by the addition of the RuII(bdq)(NO)(tpy)3+ (Rubdq-NO+) complex ion. After purification through a dialysis bag, the resulting CDs (CDg) exhibit fluorescent emission at 400 nm and maintained fluorescence stability in an aqueous solution (pH = 7) for 30 days under 5 ◦C. Fluorescence quenching studies revealed an electrostatic interaction between the negative charge from CDg (δ = - 20 mV) and the positively charged nitrosyl (NO+) ligand of the ruthenium complex (Rubdq-NO+), resulting in quenching of the CDg fluorescence due to the inner filter effects (IFE). The chemiluminescence reaction of CDg and Rubdq-NO-CDg in presence of norepinephrine (NOR) were evaluated. NOR in PBS are liable to undergo spontaneous oxidation to quinone form (NOR-quinone). CDg are believed interact with NOR-quinone and an electron transfer occur obtained CDg+ accompanied to green emission fluorescence (520 nm). While for Rubdq-NO-CDg in presence of NOR, the green emission occurs accompanied by NO0 release using DAF-2 probe.
Two non-symmetric free-base porphyrins, one with an electron density withdrawing group (–NO2), H2(NPTPP), and the other with an electron density donor group (–NH2), H2(APTPP), were synthesized, ...characterized and the photophysical properties reported. The compound H2(APTPP) showed a fluorescence quantum yield (ΦFl = 0.12) similar to that of H2(TPP), and this derivative showed the longer lifetime in the singlet state (τ1 = 1.51 ns and τ2 = 7.74 ns; bi-exponential process) and the ability to generate singlet oxygen. It also showed relative resistance to the photobleaching process. However, it presented a high degree of aggregation in a medium that mimicked the biological one. In cell viability tests against B16–F10 cells, H2(APTPP) did not show cytotoxic activity either in absence or presence of a light stimulus. H2(NPTPP) at 50 μM showed a reduction in cell viability (of up to 50%) under dark or light conditions. The liposomal formulation containing H2(APTPP) was stable for 2 h and caused the death of tumor cells (up to 95%) even in absence of light stimulus, showing that cell death is associated with non-photodynamic processes.
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•H2(APTPP) has a fluorescence quantum yield (Φfl = 0.12) higher than that of H2(NPTPP) (Φfl = 0.06).•H2(APTPP) produces singlet oxygen better than H2(NPTPP).•H2(NPTPP) or liposomal formulation with H2(APTPP) showed a reduction in cell viability under dark and light conditions.•The decrease in cellular viability of B16–F10 cell lines is associated with a non-photodynamic process.
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•Crude sericin extracts of Bombyx mori silk cocoons were produced via two approaches.•Sericin exhibited antioxidant and antimicrobial activities.•The crude sericin extracts had ...obvious radical scavenging effects with DPPH assay.•No cytotoxic, genotoxic and mutagenic effects whatsoever were found.•Sericin might be a valuable addition for food and biopharmaceutical applications.
In the present research effort, production of crude sericin extracts from Bombyx mori silk cocoons was attempted using two different approaches. Sericin was extracted from cocoons by high-temperature autoclaving followed either by lyophilization or freezing-thawing precipitation, to obtain a crude sericin powder. The physico-chemical and biological characteristics of the crude sericin extracts were evaluated in detail, via FTIR, XRD, XRF, XRT, UV–vis scanning, TGA and DSC, protein quantification, antimicrobial activity, free radical scavenging activity, cytotoxic activity, potential for inducing chromosomal aberrations via Allium cepa assays, and genotoxicity via Comet™ analyses. The molecular weight distribution of the crude sericin extracts was also investigated, via sodium dodecyl sulfate–polyacrylamide gel electrophoresis (SDS–PAGE), and the results duly compared to standard sericin. The results gathered clearly suggest that the crude sericin extracts had both obvious radical scavenging effects with the 2.2-diphenyl-1-picryl-hydrazil (DPPH) assay, and antibacterial activity, further suggesting that this protein might be a valuable addition for either food and biopharmaceutical applications.
Negro Teatro, Negra Performance Silva (Kabilaewatala), Renata de Lima; Peixoto, Jordana Dolores
Revista Brasileira de Estudos da Presença,
2022, Letnik:
12, Številka:
4
Journal Article
Odprti dostop
Neste artigo apresenta-se discussão sobre a noção de Performance Negra, que, atrelada ao Movimento Negro, constitui-se no conjunto de manifestações expressivas, do ritual ao espetáculo, que organizam ...cenicamente modos de existir e de resistir do povo negro na diáspora africana. O recorte metodológico é uma abordagem do macro ao micro, iniciando com uma definição geral de Movimento Negro, depois, problematizando o conceito de Performance Negra como uma categoria que pode abranger tanto performances tradicionais de cunho ritualístico como performances artísticas nas linguagens do teatro, da dança e da performance arte. Por fim, toma-se o Teatro Negro como foco de análise a partir de seus aspectos históricos.
The aim of this study was to synthesize the evidence on the prevalence of latent Mycobacterium tuberculosis infection (LTBI) among undergraduate health care students.
A systematic review of ...prevalence with meta-analysis was conducted. Prospective and retrospective cohorts and cross-sectional studies involving probable exposure to M. tuberculosis during undergraduate education, along with the tuberculin skin test (TST) or interferon-γ release assay (IGRA) for investigation of latent tuberculosis were searched. Searches were conducted in MEDLINE, CINAHL, EMBASE, LILACS, Scopus, and Web of Science databases. Independent reviewers were responsible for the selection and inclusion of studies. Data were extracted, critically appraised, and synthesized using the JBI approach. PRISMA was used to report the study.
Twenty-two studies were analyzed. The overall prevalence in healthcare undergraduate students was 12.53%.
The prevalence of LTBI in undergraduate health students was high for such a highly educated population. Screening with TST and/or IGRA and chemoprophylaxis, when necessary, should be provided to undergraduate health students when in contact with respiratory symptomatic patients.
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