Bringing a diagnostic point of care test (POCT) to a healthcare market can be a painful experience as it requires the manufacturer to meet considerable technical, financial, managerial, and ...regulatory challenges. In this opinion article we propose a framework for developing the evidence needed to support product development, marketing, and adoption. We discuss each step in the evidence development pathway from the invention phase to the implementation of a new POCT in the healthcare system. We highlight the importance of articulating the value propositions and documenting the care pathway. We provide guidance on how to conduct care pathway analysis as little has been published on this. We summarize the clinical, economic and qualitative studies to be considered for developing evidence, and provide useful links to relevant software, on-line applications, websites, and give practical advice. We also provide advice on patient and public involvement and engagement (PPIE), and on product management. Our aim is to help device manufacturers to understand the concepts and terminology used in evaluation of
diagnostics (IVDs) so that they can communicate effectively with evaluation methodologists, statisticians, and health economists. Manufacturers of medical tests and devices can use the proposed framework to plan their evidence development strategy in alignment with device development, applications for regulatory approval, and publication.
(1) Background: Given the high prevalence of non-alcoholic fatty liver disease (NAFLD) and the limitations of liver biopsies, multiple non-invasive tests (NITs) have been developed to identify ...non-alcoholic fatty liver disease (NAFLD) patients at-risk of progression. The availability of these new NITs varies from country to country, and little is known about their implementation and adoption in routine clinical practice. This study aims to explore barriers and facilitators that influence the adoption of NAFLD NITs, from healthcare professionals' perspectives. (2) Methods: A cross-sectional study was performed using an exploratory mixed-methods approach. Twenty-seven clinicians from eight different countries with different specialties filled in our questionnaire. Of those, 16 participated in semi-structured interviews. Qualitative and quantitative data were collected and summarized using the recently published Non-adoption, Abandonment, Scale-up, Spread, and Sustainability (NASSS) framework for new medical technologies in healthcare organizations. (3) Results: Several factors were reported as influencing the uptake of NITs for NAFLD in clinical practice. Among those: insufficient awareness of tests; lack of practical guidelines and evidence for the performance of tests in appropriate patient populations and care settings; and absence of sufficient reimbursement systems were reported as the most important barriers. Other factors, most notably 'local champions', proper functional payment systems, and sufficient resources in academic hospitals, were indicated as important facilitating factors. (4) Conclusions: Clinicians see the adoption of NITs for NAFLD as a complex process that is modulated by several factors, such as robust evidence, practical guidelines, a proper payment system, and local champions. Future research could explore perspectives from other stakeholders on the adoption of NITs.
The purpose of this research is to investigate how logistics outsourcing performs activities that have been traditionally carried out within the outsourcer’s company. The study examines the ...characteristics of logistics and transport services, which are important in cooperation with service providers. Two groups were formed according to the average values of the characteristics of logistics activities. ‘Cost, quality and response’ are important for the first group, while ‘logistics, environment and the ability to adapt to client processes’ are important for the second group. The results of the survey carried out in Slovenian enterprises show that both groups are primarily interested in express freight and shipment services, the difference lying in the understanding of logistics, mutual trust and brand recognition. The findings will be useful both in business practice and for managers, providing them with a better understanding of the performance of logistics outsourcing.
The evolution of organizational processes and performance over the past decade has been largely enabled by cutting-edge technologies such as data analytics, artificial intelligence (AI), and business ...intelligence applications. The increasing use of cutting-edge technologies has boosted effectiveness, efficiency and productivity, as existing and new knowledge within an organization continues to improve AI abilities. Consequently, AI can identify redundancies within business processes and offer optimal resource utilization for improved performance. However, the lack of integration of existing and new knowledge makes it problematic to ascertain the required nature of knowledge needed for AI’s ability to optimally improve organizational performance. Hence, organizations continue to face reoccurring challenges in their business processes, competition, technological advancement and finding new solutions in a fast-changing society. To address this knowledge gap, this study applies a fuzzy set-theoretic approach underpinned by the conceptualization of AI, knowledge sharing (KS) and organizational performance (OP). Our result suggests that the implementation of AI technologies alone is not sufficient in improving organizational performance. Rather, a complementary system that combines AI and KS provides a more sustainable organizational performance strategy for business operations in a constantly changing digitized society.
In the last decade, food and drink supply chain management has become an important part of global operations strategy. The global food and drink industries (FDIs) is establishing supply chain ...operations across countries as a result of increasing demand, this expansion has created challenges in coordinating operations that connect multi-suppliers, one as such is the financial enabler for the multi-layered supply chain network. However, literature on artificial intelligence (AI) in FDIs is limited, this study explores AI theory in supply chain networks and alternative supply chain financing for the FDIs. This study proposes a new conceptual framework based on theoretical contributions identified through literature, a conceptual framework is established and further developed to a meta-framework. This study explored the set-theoretic comparative approach for data analysis, the outcomes of this research suggest that the probable contributions of supply chain networks driven by AI technologies provide a sustainable financing stream for the food and drink supply chain.
The increasing use of digital technologies has significantly reshaped marketing and consumer behavior (CB) as online communities and cutting-edge innovations such as artificial intelligence (AI) ...disrupt and advance consumer attitudes on specific products and services. As such, online communities that are supported by AI technologies creating new knowledge from consumer interactions through platforms like social media as consumers share experiences on specific products or services. Since AI is designed to "learn" and improve with data generated from digital technologies linked to consumer interactions, AI relies on consumer knowledge-sharing (KS) activities to replicate new knowledge for product and service improvement. However, given the knowledge gap in this area, this article applies the fsQCA technique to data generated from 291 participants to develop CB metaframework predicted on the concepts of AI, CB, and KS. Our results suggest that AI advances consumer attitudes and behaviors when knowledge is acquired while online communities promote curiosity and engage consumers to learn by sharing experiences about specific products or services. Furthermore, understanding the causality between AI, CB, and KS concepts offers critical decision-making insights to marketing experts across the industry.
Respiratory syncytial virus is a common cause of bronchiolitis. Historically, point-of-care tests have involved antigen detection technology with limited sensitivity. The aim of this study was to ...prospectively evaluate the diagnostic accuracy and model the economic impact of the Roche cobas® Liat® point-of-care influenza A/B and respiratory syncytial virus test.
The “DEC-RSV” study was a multi-centre, prospective, observational study in children under 2 years presenting with viral respiratory symptoms. A nasopharyngeal aspirate sample was tested using the point-of-care test and standard laboratory-based procedures. The primary outcome was accuracy of respiratory syncytial virus detection. The cost implications of adopting a point-of-care test were modelled using study data.
A total of 186 participants were recruited, with both tests performed on 177 samples. The point-of-care test was invalid for 16 samples (diagnostic yield 91%) leaving 161 available for primary analysis. After resolving discrepancies, the cobas® Liat® respiratory syncytial virus test had 100.00% (95% CI 96.07%–100.00%) sensitivity and 98.53% (95% CI 92.08%–99.96%) specificity. Median time to result was 0.6 h (interquartile range (IQR) 0.5–1) for point-of-care testing and 28.9 h (IQR 26.3–48.1) for standard laboratory testing. Estimated non-diagnostic cost savings for 1000 patients, based on isolation decision-making on point-of-care test result, were £57 010, which would increase to £94 847 when cohort nursing is used.
In young children the cobas® Liat® point-of-care respiratory syncytial virus test has high diagnostic accuracy using nasopharyngeal aspirates (currently an off-licence sample type). Time to result is clinically important and was favourable compared to laboratory-based testing. The potential exists for cost savings when adopting the point-of-care test.
Fake news on Social Media: the Impact on Society Olan, Femi; Jayawickrama, Uchitha; Arakpogun, Emmanuel Ogiemwonyi ...
Information systems frontiers,
04/2024, Letnik:
26, Številka:
2
Journal Article
Recenzirano
Odprti dostop
Fake news (FN) on social media (SM) rose to prominence in 2016 during the United States of America presidential election, leading people to question science, true news (TN), and societal norms. FN is ...increasingly affecting societal values, changing opinions on critical issues and topics as well as redefining facts, truths, and beliefs. To understand the degree to which FN has changed society and the meaning of FN, this study proposes a novel conceptual framework derived from the literature on FN, SM, and societal acceptance theory. The conceptual framework is developed into a meta-framework that analyzes survey data from 356 respondents. This study explored fuzzy set-theoretic comparative analysis; the outcomes of this research suggest that societies are split on differentiating TN from FN. The results also show splits in societal values. Overall, this study provides a new perspective on how FN on SM is disintegrating societies and replacing TN with FN.
Local and regional similarities and differences in the organisational culture of the national postal operator were discussed. Its business units are present in all Slovenian regions. The main ...objective of the research is to discover the prevailing type of the organisational culture in the company. For this purpose, we used Cameron and Quinn's questionnaire. We suppose that among certain business units in different Slovenian regions there are both affinities and substantial differences in the perception of the organisational culture. The results showed that we can classify business units of the organisation according to the organisational culture in two heterogeneous groups.
Supply chain finance (SCF) is receiving increasing awareness in research as a result of uncertainties in the global financing for supply chain (SC). There are limited and fragmented studies in the ...implementations of financial services in SC management. This article builds on recovery from the financial crisis of 2008 and posts COVID-19 pandemic, where uncertainties crippled SCF providers and brokers services. At the same time, cutting-edge technological advancements such as Artificial Intelligence (AI) are revolutionizing the processes of business ecosystem in which SCF is entrenched. This article thus adopts a fuzzy set theoretical approach to unpack the entities relationship validity for sustainable SCF mate-framework, and the originality of AI concepts to sustainable SCF to identify the issues and inefficiencies. The results indicate that AI contributes significant economic opportunities and deliver the most effective utilization of the supply networks. In addition, the article provides a theoretical contribution to financing in SC and broadens the managerial implications in improving performance.
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