Assessment of high-density polyethylene (HDPE)-degrading bacteria isolated from plastic waste dumpsites of Gulf of Mannar. Rationally, 15 bacteria (GMB1-GMB15) were isolated by enrichment technique. ...GMB5 and GMB7 were selected for further studies based on their efficiency to degrade the HDPE and identified as Arthrobacter sp. and Pseudomonas sp., respectively. Assessed weight loss of HDPE after 30 days of incubation was nearly 12% for Arthrobacter sp. and 15% for Pseudomonas sp. The bacterial adhesion to hydrocarbon (BATH) assay showed that the cell surface hydrophobicity of Pseudomonas sp. was higher than Arthrobacter sp. Both fluorescein diacetate hydrolysis and protein content of the biofilm were used to test the viability and protein density of the biomass. Acute peak elevation was observed between 2 and 5 days of inoculation for both bacteria. Fourier transform infrared (FT-IR) spectrum showed that keto carbonyl bond index (KCBI), Ester carbonyl bond index (ECBI) and Vinyl bond index (VBI) were increased indicating changes in functional group(s) and/or side chain modification confirming the biodegradation. The results pose us to suggest that both Pseudomonas sp. and Arthrobacter sp. were proven efficient to degrade HDPE, albeit the former was more efficacious, yet the ability of latter cannot be neglected. Recent alarm on ecological threats to marine system is dumping plastic waste in the marine ecosystem and coastal arena by anthropogenic activity. In maintenance phase of the plastic-derived polyethylene waste, the microbial degradation plays a major role; the information accomplished in this work will be the initiating point for the degradation of polyethylene by indigenous bacterial population in the marine ecosystem and provides a novel eco-friendly solution in eco-management.
•Mass screening for loss of protective sensation can help prevent diabetic ulcers.•The Ipswich touch test is valid in people without diabetic foot ulceration history.•Its ease-of-use and cost-free ...nature makes it ideal for mass screening.•Repeating VibratipTM testing for the hallux, 3rd and 5th toe improves performance.•The use of VibratipTM for mass screening is not supported by our results.
The ability of the Ipswich touch test (IpTT) and VibratipTM to detect loss of protective sensation (LOPS) was tested against a neurothesiometer in an outpatient diabetic population without a history for ulceration. Our results support the use of the IpTT as a screening tool for LOPS, but not of VibratipTM.
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•Functionalization of NPs for high output biomedical applications.•Magnetothermal NPs in drug delivery.•Nanotechnology: Smart ligands and antibodies targets in cancer biology.
In the ...scientific field, nanotechnology has offered multipurpose and designated functional nanoparticles (NPs) for the development of applications in nano-medicine. This present review focuses on cutting edge of nanotechnology in biomedical applications as drug carries in cancer treatment. The nanotechnology overcomes several limitations of drug delivery systems used in distinct therapeutic approaches of cancer treatment. The serious effect of conventional chemotherapeutics by nonspecific targeting, the lack of solubility, and the inability of chemotherapeutics entry to cancer cells which, offers a great opportunity for nanotechnology to play significant roles in cancer biology. The selective delivery of nano-drugs to the targeted cancer cells by the programmed way and avoiding nonspecific interactions to the healthy cells. The present review focuses on the methods of improving the size, shape and characteristics of nanomaterials which can be exploited for cancer therapy. The successful designing of nanocarriers can be tailored for cancer treatment for upcoming future as nano-medicines.
Aim: To determine the optimum level of phosphorus for higher yield and phosphorus uptake by groundnut at different planting densities. Methodology: A field experiment was laid out in randomized block ...design with factorial concept during Rabi seaon 2019-20 to study the phosphorus uptake by groundnut under high density plantation (22.5 x 10 cm - 4.44 lakh ha-1; 20 x 7.5 cm - 6.66 lakh ha-1; 22.5 x 5 cm - 8.88 lakh ha-1 with graded levels of phosphorus (25, 37.5, 50 and 62.5 kg P2O5 ha-1). Results: The present study revealed that 4.44 lakh ha-1 registered lower phosphorus uptake and application of 62.5 kg P2O5 ha-1 recorded a higher uptake of phosphorus and soil available nitrogen, phosphorus, and potassium. Interaction was significant only in influencing pod yield. Higher pod yield was recorded in the population density of 4.44 lakh ha-1 applied along with 50 kg P2O5 ha-1, followed by 6.66 lakh ha-1 applied with 62.5 kg P2O5 ha-1. Interpretation: The results indicate that for better nutrient uptake and higher pod yield of groundnut, farmers should prefer a planting density of 6.66 lakh ha-1 with an application of 62.5 kg P2O5 ha-1. Key words: Groundnut, Nutrient uptake, Plant density, Phosphorus, Pod yield
Inter satellite optical wireless communication (IsOWC) is an emerging transmission technology which is capable of transporting high-speed data between two satellites estranged in outer space and ...revolving in the same or different orbits. IsOWC links have been considered very crucial for the purpose of providing global coverage for information transmission throughout the world. This work reports the modeling and performance investigation of a novel hybrid wavelength division multiplexing–polarization division multiplexing based IsOWC transmission system incorporating an orthogonal modulation scheme combining carrier suppressed return to zero–differential quadrature phase shift keying–polarization shift keying formats to transmit three independent 40 Gbps data streams simultaneously at different signal parameters. The results show a successful transmission of 3.84 Tbps information over 58,000 km link range with acceptable Q Factor (> 6 dB) and BER (≤ 10
−9
) using the proposed system. The performance comparison of the proposed system with existing work has also been discussed in this paper.
A BSTRACT Background: Neurodegenerative diseases induce amnesia, and effective treatment is still elusive. Aims and Objectives: The present study highlights the ameliorating effects of Manasa Mitra ...Vatakam (MMV) using behavioral parameters on scopolamine-induced memory loss in female Wistar rats. Materials and Methods: MMV was compared with DPZ as a standard in the present study to determine the behavioral parameters through elevated plus maze (Hebb William maze/rectangular maze)and locomotor activity in scopolamine-induced memory loss in female Wistar rats. Results and Discussion: The results of the study illustrate the effectiveness of MMV in reversing memory dysfunction and memory-enhancing effects. Conclusion: The study paves the way for exploring research in CNS disorders and its potential application in drug-induced neurotoxicity.
A BSTRACT Background: The scientific validity of contemporary and alternative medicinal practices, such as Ayurveda and Siddha, holds significant importance in today’s context. Aim and Objective: The ...present study employs gas chromatography-mass spectrometry (GC-MS) analysis to investigate a pain-relieving Ayurvedic oil, Dhanwantharam Thailam, aiming to establish correlations between its medicinal activity and the biomolecules it contains. Materials and Methods: Procured sample from a reputable Ayurvedic vendor in Chennai, Dhanwantharam Thailam underwent GC-MS analysis using standard procedures. Results and Discussion: The resulting profile revealed the presence of crucial molecules like oleic acid, dodecanoic acid, 1,2,3-propanetriyl ester, ethenyl ester, and 9,12-octadecadienoyl chloride (Z, Z), aligning with the medicinal properties attributed to Dhanwantharam Thailam. Conclusion: The identification of these biomolecules supports the role of Dhanwantharam Thailamas an effective pain-relieving oil.
Information and Communication Technologies have become more prevalent in the last few years and has made a great impact on society. Worldwide, a lot of education programs offer new forms of education ...that are frequently supported by information and communication technology (ICT) to cater to young minds. E-learning in particular has been adopted by educational institutions all over the world and it is being used as a part of “blended learning” where it is incorporated into systems along with traditional classroom learning. Nowadays, it has become more relevant than ever due to the COVID-19 pandemic that the world is facing. Although these systems differ from classroom learning, they allow easy communication among teachers and students at any time necessary and provide an entire repository for students to use. For teachers, it acts as an environment for creating courses, assignments, giving feedback and grading students. In this paper, two such E-learning platforms namely Moodle and Google Classroom are compared and contrasted based on their usability and simplicity.
The utilization of herbal formulations for the management of reproductive tract disorders has been a longstanding practice in traditional medicine. In this study, we investigated the efficacy of a ...herbal extract, Shalmali (Bombax ceiba), in addressing uterine bleeding, a common concern in gynecological health. Through gene expression analysis, this study examined the impact of Shalmali extract on key genes associated with uterine bleeding, namely ESR1, CD56, and SDF-1, in the human endometrial stromal cell line (T HESC). Our findings revealed a dose-dependent decrease in ESR1 and CD56 gene expression levels following treatment with Shalmali extract, suggesting its potential to modulate hormonal and cellular processes involved in uterine bleeding. Notably, an increase in SDF-1 gene expression was observed, indicating a possible role of Shalmali extract in promoting tissue repair and regeneration. Comparison with the standard drug tranexamic acid demonstrated similar effects on gene expression levels, further validating the therapeutic potential of Shalmali extract. Agarose gel electrophoresis images supported these findings, showing reduced gene expression in cells treated with Shalmali extract comparable to those treated with tranexamic acid. These results underscore the promising efficacy of Shalmali extract as a natural alternative for managing uterine bleeding, potentially offering a safe and effective treatment option for individuals seeking traditional remedies for gynecological concerns. Further research is warranted to elucidate the underlying mechanisms of action and assess the long-term safety and efficacy of Shalmali extract in clinical settings.
Previous prospective studies on the association of white rice intake with incident diabetes have shown contradictory results but were conducted in single countries and predominantly in Asia. We ...report on the association of white rice with risk of diabetes in the multinational Prospective Urban Rural Epidemiology (PURE) study.
Data on 132,373 individuals aged 35-70 years from 21 countries were analyzed. White rice consumption (cooked) was categorized as <150, ≥150 to <300, ≥300 to <450, and ≥450 g/day, based on one cup of cooked rice = 150 g. The primary outcome was incident diabetes. Hazard ratios (HRs) were calculated using a multivariable Cox frailty model.
During a mean follow-up period of 9.5 years, 6,129 individuals without baseline diabetes developed incident diabetes. In the overall cohort, higher intake of white rice (≥450 g/day compared with <150 g/day) was associated with increased risk of diabetes (HR 1.20; 95% CI 1.02-1.40;
for trend = 0.003). However, the highest risk was seen in South Asia (HR 1.61; 95% CI 1.13-2.30;
for trend = 0.02), followed by other regions of the world (which included South East Asia, Middle East, South America, North America, Europe, and Africa) (HR 1.41; 95% CI 1.08-1.86;
for trend = 0.01), while in China there was no significant association (HR 1.04; 95% CI 0.77-1.40;
for trend = 0.38).
Higher consumption of white rice is associated with an increased risk of incident diabetes with the strongest association being observed in South Asia, while in other regions, a modest, nonsignificant association was seen.
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