This article considers how the metaphor of Mother Earth, for women, concerns a dual stance of both belonging and distance. The link between women, nature and Mother Earth is problematised by ...considering the possible, or contested, link between population growth and climate change, and the South African population policy specifically is considered as an example. Ecofeminism’s challenge to the perceived connection between women, motherhood and Earth, that is the ‘distance’ stance, is considered and a response to that is offered by reflecting on Mercy Oduyoye’s notion of mothering, which represents the ‘belonging’ stance. In this regard, an intercultural approach to the definition of motherhood is implied. It is ultimately indicated that for women to reclaim their own agency regarding a perceived responsibility towards nature, it is necessary to deconstruct and reconstruct ‘motherhood’ to free themselves from being stuck between Mother Earth and a mother’s womb.Contribution This article makes a contribution to feminist studies at the intersection of gender roles and the climate crisis, as it relates to population growth and an intercultural definition of motherhood. It contributes to UN’s sustainable development agenda as it relates to both SDG 5 (gender equality) and SDG 13 (climate action).
Over the past few years, there has been a significant intellectual and artistic emphasis on the manner in which one considers or approaches the end of life. This is in conjunction with a renewed ...ethical discussion about choosing the manner and time of one's death in light of a diminished quality of life. Large populations across the world are ageing, presenting unique challenges to healthcare and civic infrastructure. The planet is suffering because of a climate crisis, due to the overburdening of resources. In light of all this, it is argued in this contribution that a renewed theological consideration of death is necessary. In his theology about the Trinity, Jürgen Moltmann makes a remark about his understanding of the perichoretic unity of the persons of the Trinity, in which the persons of the Trinity “cede” space for one another. Ceding space creates space (room) for authentic existence. This contribution considers and utilises Trinitarian “spatial” theology as foundation for rethinking the complexity and balance of life and death. It is ultimately argued that “creating space for death” could serve as a foundation for an ethical framework for decisionmaking, as well as foster a compassionate community that provides space for each other's diversity - in life and in death.
In this contribution, the connection between redressing the past and doing justice in the present is explored by presenting the notion of ‘paradox’ as a response to ‘binary thinking’. In this regard, ...‘paradox’ denotes contradictory, yet interrelated aspects that exist simultaneously. ‘Binary thinking’ refers to either/or categorical aspects that cannot co-exist. Two paradoxes are explored as a response to increasing polarisation because of a struggle in redressing past injustices: the paradox of remembering and forgetting and the paradox of difference and sameness. This is done by bringing the work of the South African practical theologian, Denise Ackermann, in conversation with the work of the Croatian systematic theologian, Miroslav Volf. From different origins and experiences, both offer a way forward, and a way to move on beyond the devastation that is caused by dealing with injustice, difference and memory in a polarising fashion. The contribution concludes with a reflection on the notion of ‘ceding space’ from a Trinitarian theological perspective. The ceding of space is proposed as act of transformation, as the outcome of the ideas proposed by Ackermann and Volf, and as a way to live together, ‘after the locusts’.
In this article, Christi van der Westhuizen’s sociopolitical contribution in her publication, Sitting Pretty: White Afrikaans Women in Postapartheid South Africa, is reviewed. In light of the ...official end of apartheid in 1994, South Africans are attempting to define a new identity. Van der Westhuizen’s publication focusses on how the identity of white Afrikaans women, as both the oppressor and the oppressed, influences and contributes to the endeavour of a search for new identity. In deconstructing and re-imagining new identity, Van der Westhuizen deconstructs the ‘supporting scaffolding’ of Afrikaner identity and examines the impact of white patriarchal hegemony that silences the voice of women, sexual minorities and black consciousness. The review concludes with the emphasis on the transformative role of shame, that is, the willingness to expose the false sense of goodness that we had of ourselves, as pointed out by Van der Westhuizen. In this regard, the recognition of the intersectionality of people’s experiences becomes a key aspect of the endeavour of a search for new identity.
In hierdie hoofstuk word Jürgen Moltmann se bydrae tot Reformatoriese teologie ondersoek. Sy teologie kan beskryf word as 'n teologie wat Bybels gegrond is, 'n eskatologiese gerigtheid en 'n ...politieke verantwoordelikheid het. Dit is juis om hierdie rede dat sy teologie ook 'reformatories' is. Dit is 'n beskrywing waarvoor hy ook doelbewus kies, omdat die begrip 'reformatories' die dinamiese, voortgaande en profetiese karakter van Reformatoriese teologie aandui. Hierdie teologiese karakter kom veral na vore in Moltmann se verstaan van die Triniteitsleer en sy trinitariese teologie, wat beskryf kan word as 'n 'Trinitariese teologie van solidariteit en sosiale geregtigheid.' Die lewensruimte van die Triniteit word deur Moltmann as 'wye ruimte' beskryf, en as 'n 'uitnodigende ruimte' waarin daar nie beknoptheid is nie. Binne die hoofstuk word dit geargumenteer dat Moltmann se Triniteitsteologie die hartklop is van sy bydrae tot Reformatoriese teologie. Dit is baie nou verbind aan sy politieke teologie en word geïllustreer op die wyse waarop sy Triniteitsteologie en sy politieke teologie van inklusiwiteit en geregtigheid met mekaar verweef is.
Novel chemical tools to eliminate malaria should ideally target both the asexual parasites and transmissible gametocytes. Several imidazopyridazines (IMPs) and 2-aminopyridines (2-APs) have been ...described as potent antimalarial candidates targeting lipid kinases. However, these have not been extensively explored for stage-specific inhibition of gametocytes in Plasmodium falciparum parasites. Here we provide an in-depth evaluation of the gametocytocidal activity of compounds from these chemotypes and identify novel starting points for dual-acting antimalarials.
We evaluated compounds against P. falciparum gametocytes using several assay platforms for cross-validation and stringently identified hits that were further profiled for stage specificity, speed of action and ex vivo efficacy. Physicochemical feature extraction and chemogenomic fingerprinting were applied to explore the kinase inhibition susceptibility profile.
We identified 34 compounds with submicromolar activity against late stage gametocytes, validated across several assay platforms. Of these, 12 were potent at <100 nM (8 were IMPs and 4 were 2-APs) and were also active against early stage gametocytes and asexual parasites, with >1000-fold selectivity towards the parasite over mammalian cells. Front-runner compounds targeted mature gametocytes within 48 h and blocked transmission to mosquitoes. The resultant chemogenomic fingerprint of parasites treated with the lead compounds revealed the importance of targeting kinases in asexual parasites and gametocytes.
This study encompasses an in-depth evaluation of the kinase inhibitor space for gametocytocidal activity. Potent lead compounds have enticing dual activities and highlight the importance of targeting the kinase superfamily in malaria elimination strategies.
This article can serve as an overview of the work of Yolanda Dreyer, or as an introduction to her work, by conversing with her as a public theologian in the tradition of Schleiermacher. The article ...highlights her passion to listen to the voices that are normally ignored or to hear what needs to be heard to transform discourses. It investigates the contribution of Yolanda Dreyer to public theology with regard to the newspaper columns she has been writing for more than 17 years. It compares aspects of her public theology with the theology of Friedrich Schleiermacher, which can be characterised by an internalised spirituality and a critical hermeneutic of suspicion towards the abuse of power. Gender injustice and cultural criticism are prominent themes within Dreyer’s public theology. She emphasises the vocation to speak out, but also the necessity to listen. These contributions also characterise Dreyer as a pastortheologian.
The contribution of two women to the Reformed heritage: The life and work of Frances Young (1939–) and Dorothee Sölle (1929–2003). This article is a lexicographical overview of the life and work of ...two specific women, Frances Young and Dorothee Sölle. The purpose of this is to highlight the reformed character of their respective theologies. Both are characterised by reflection on and reaction to the fragility of human life and the brokenness of the human condition. They are among the ‘cloud of witnesses’ that bear testimony to the impact and heritage of the Reformation.
This contribution is a political-theological and hermeneutical reflection on the origin, nature, intention and contribution of a research theme identified within the dynamics of an institutional ...space, by taking a critical look at the ‘rules’ and the ‘game’ of university academia. Specific reference is made to institutional and faculty research themes, namely ‘reconciling diversity’ and ‘Ecodomy – life in its fullness’. The institutional academic space is compared to a Hunger Games-style panopticon, with its ‘rules’ and ‘play’. It is argued that these research themes can only make an authentic contribution if the ‘play’ and ‘game’of the space in which these themes originate, are deconstructed. If this deconstruction can take place, there might be an authentic chance for unhindered dialogue towards the transformation of the academic space and the greater community it serves.
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