We report the discovery and characterization of two transiting planets around the bright M1 V star LP 961-53 (TOI-776,
J
= 8.5 mag,
M
= 0.54 ± 0.03
M
⊙
) detected during Sector 10 observations of the ...Transiting Exoplanet Survey Satellite (TESS). Combining the TESS photometry with HARPS radial velocities, as well as ground-based follow-up transit observations from the MEarth and LCOGT telescopes, for the inner planet, TOI-776 b, we measured a period of
P
b
= 8.25 d, a radius of
R
b
= 1.85 ± 0.13
R
⊕
, and a mass of
M
b
= 4.0 ± 0.9
M
⊕
; and for the outer planet, TOI-776 c, a period of
P
c
= 15.66 d, a radius of
R
c
= 2.02 ± 0.14
R
⊕
, and a mass of
M
c
= 5.3 ± 1.8
M
⊕
. The Doppler data shows one additional signal, with a period of ~34 d, associated with the rotational period of the star. The analysis of fifteen years of ground-based photometric monitoring data and the inspection of different spectral line indicators confirm this assumption. The bulk densities of TOI-776 b and c allow for a wide range of possible interior and atmospheric compositions. However, both planets have retained a significant atmosphere, with slightly different envelope mass fractions. Thanks to their location near the radius gap for M dwarfs, we can start to explore the mechanism(s) responsible for the radius valley emergence around low-mass stars as compared to solar-like stars. While a larger sample of well-characterized planets in this parameter space is still needed to draw firm conclusions, we tentatively estimate that the stellar mass below which thermally-driven mass loss is no longer the main formation pathway for sculpting the radius valley is between 0.63 and 0.54
M
⊙
. Due to the brightness of the star, the TOI-776 system is also an excellent target for the
James Webb
Space Telescope, providing a remarkable laboratory in which to break the degeneracy in planetary interior models and to test formation and evolution theories of small planets around low-mass stars.
Structure-based design of vaccines, particularly the iterative optimization used so successfully in the structure-based design of drugs, has been a long-sought goal. We previously developed a ...first-generation vaccine antigen called DS-Cav1, comprising a prefusion-stabilized form of the fusion (F) glycoprotein, which elicits high-titer protective responses against respiratory syncytial virus (RSV) in mice and macaques. Here we report the improvement of DS-Cav1 through iterative cycles of structure-based design that significantly increased the titer of RSV-protective responses. The resultant second-generation 'DS2'-stabilized immunogens have their F subunits genetically linked, their fusion peptides deleted and their interprotomer movements stabilized by an additional disulfide bond. These DS2 immunogens are promising vaccine candidates with superior attributes, such as their lack of a requirement for furin cleavage and their increased antigenic stability against heat inactivation. The iterative structure-based improvement described here may have utility in the optimization of other vaccine antigens.
Context.
Several planetary formation models have been proposed to explain the observed abundance and variety of compositions of super-Earths and mini-Neptunes. In this context, multitransiting ...systems orbiting low-mass stars whose planets are close to the radius valley are benchmark systems, which help to elucidate which formation model dominates.
Aims.
We report the discovery, validation, and initial characterization of one such system, TOI-2096 (TIC 142748283), a two-planet system composed of a super-Earth and a mini-Neptune hosted by a mid-type M dwarf located 48 pc away.
Methods.
We characterized the host star by combining optical spectra, analyzing its broadband spectral energy distribution, and using evolutionary models for low-mass stars. Then, we derived the planetary properties by modeling the photometric data from TESS and ground-based facilities. In addition, we used archival data, high-resolution imaging, and statistical validation to support our planetary interpretation.
Results.
We found that the stellar properties of TOI-2096 correspond to a dwarf star of spectral type M4±0.5. It harbors a super-Earth (
R
= 1.24 ± 0.07
R
⊕
) and a mini-Neptune (
R
= 1.90 ± 0.09
R
⊕
) in likely slightly eccentric orbits with orbital periods of 3.12 d and 6.39 d, respectively. These orbital periods are close to the first-order 2:1 mean-motion resonance (MMR), a configuration that may lead to measurable transit timing variations (TTVs). We computed the expected TTVs amplitude for each planet and found that they might be measurable with high-precision photometry delivering mid-transit times with accuracies of ≲2 min. Moreover, we conclude that measuring the planetary masses via radial velocities (RVs) could also be possible. Lastly, we found that these planets are among the best in their class to conduct atmospheric studies using the NIRSpec/Prism onboard the
James Webb
Space Telescope (JWST).
Conclusions.
The properties of this system make it a suitable candidate for further studies, particularly for mass determination using RVs and/or TTVs, decreasing the scarcity of systems that can be used to test planetary formation models around low-mass stars.
Context . Long-period transiting exoplanets bridge the gap between the bulk of transit- and Doppler-based exoplanet discoveries, providing key insights into the formation and evolution of planetary ...systems. The wider separation between these planets and their host stars results in the exoplanets typically experiencing less radiation from their host stars; hence, they should maintain more of their original atmospheres, which can be probed during transit via transmission spectroscopy. Although the known population of long-period transiting exoplanets is relatively sparse, surveys performed by the Transiting Exoplanet Survey Satellite (TESS) and the Next Generation Transit Survey (NGTS) are now discovering new exoplanets to fill in this crucial region of the exoplanetary parameter space. Aims . This study aims to characterise a new long-period transiting exoplanet by following up on a single-transit candidate found in the TESS mission. Methods . The TOI-4862 system was monitored using a combination of photometric instruments (TESS, NGTS, and EulerCam) and spectroscopic instruments (CORALIE, FEROS, HARPS, and PFS) in order to determine the period, radius, and mass of the long-period transiting exoplanet NGTS-30 b/TOI-4862 b. These observations were then fitted simultaneously to determine precise values for the properties and orbital parameters of the exoplanet, as well as the refined stellar parameters of the host star. Results . We present the discovery of a long-period ( P = 98.29838 ± 0.00010 day) Jupiter-sized (0.928 ± 0.032 R J ; 0.960 ± 0.056 M J ) planet transiting a 1.1 Gyr old G-type star, one of the youngest warm Jupiters discovered to date. NGTS-30 b/TOI-4862 b has a moderate eccentricity (0.294 −0.010 +0.014 ), meaning that its equilibrium temperature can be expected to vary from 274 −46 +30 K to 500 −84 +55 K over the course of its orbit. Through interior modelling, NGTS-30 b/TOI-4862b was found to have a heavy element mass fraction of 0.23 −0.06 +0.05 and a heavy element enrichment ( Z p / Z ★ ) of 20 −6 +5 , making it metal-enriched compared to its host star. Conclusions . NGTS-30 b/TOI-4862 b is one of the youngest well-characterised long-period exoplanets found to date and will therefore be important in the quest to understanding the formation and evolution of exoplanets across the full range of orbital separations and ages.
We present the confirmation of a new sub-Neptune close to the transition between super-Earths and sub-Neptunes transiting the M2 dwarf TOI-269 (TIC 220 479 565,
V
= 14.4 mag,
J
= 10.9 mag,
R
⋆
= ...0.40
R
⊙
,
M
⋆
= 0.39
M
⊙
,
d
= 57 pc). The exoplanet candidate has been identified in multiple TESS sectors, and validated with high-precision spectroscopy from HARPS and ground-based photometric follow-up from ExTrA and LCO-CTIO. We determined mass, radius, and bulk density of the exoplanet by jointly modeling both photometry and radial velocities with
juliet
. The transiting exoplanet has an orbital period of
P
= 3.6977104 ± 0.0000037 days, a radius of 2.77 ± 0.12
R
⊕
, and a mass of 8.8 ± 1.4
M
⊕
. Since TOI-269 b lies among the best targets of its category for atmospheric characterization, it would be interesting to probe the atmosphere of this exoplanet with transmission spectroscopy in order to compare it to other sub-Neptunes. With an eccentricity
e
= 0.425
−0.086
+0.082
, TOI-269 b has one of the highest eccentricities of the exoplanets with periods less than 10 days. The star being likely a few Gyr old, this system does not appear to be dynamically young. We surmise TOI-269 b may have acquired its high eccentricity as it migrated inward through planet-planet interactions.
Context.
We report the discovery of TOI 263.01 (TIC 120916706), a transiting substellar object (
R
= 0.87
R
Jup
) orbiting a faint M3.5 V dwarf (
V
= 18.97) on a 0.56 d orbit.
Aims.
We setout to ...determine the nature of the Transiting Exoplanet Survey Satellite (TESS) planet candidate TOI 263.01 using ground-based multicolour transit photometry. The host star is faint, which makes radial-velocity confirmation challenging, but the large transit depth makes the candidate suitable for validation through multicolour photometry.
Methods.
Our analysis combines three transits observed simultaneously in
r
′,
i
′, and
z
s
bands usingthe MuSCAT2 multicolour imager, three LCOGT-observed transit light curves in
g
′,
r
′, and
i
′ bands, a TESS light curve from Sector 3, and a low-resolution spectrum for stellar characterisation observed with the ALFOSC spectrograph. We modelled the light curves with P
Y
T
RANSIT
using a transit model that includes a physics-based light contamination component, allowing us to estimate the contamination from unresolved sources from the multicolour photometry. Using this information we were able to derive the true planet–star radius ratio marginalised over the contamination allowed by the photometry.Combining this with the stellar radius, we were able to make a reliable estimate of the absolute radius of the object.
Results.
The ground-based photometry strongly excludes contamination from unresolved sources with a significant colour difference to TOI 263. Furthermore, contamination from sources of the same stellar type as the host is constrained to levels where the true radius ratio posterior has a median of 0.217 and a 99 percentile of0.286. The median and maximum radius ratios correspond to absolute planet radii of 0.87 and 1.41
R
Jup
, respectively,which confirms the substellar nature of the planet candidate. The object is either a giant planetor a brown dwarf (BD) located deep inside the so-called “brown dwarf desert”. Both possibilities offer a challenge to current planet/BD formation models and make TOI 263.01 an object that merits in-depth follow-up studies.
Marine oomycetous species produce, among other fatty acids, omega-6 arachidonic acid (ARA) and omega-3 eicosapentaenoic acid (EPA), with implications for the industrial potential of this group of ...organisms and the need to find an isolate with high production. This study screened 14 isolates of marine oomycetous species:
,
,
,
and
cultured from fallen mangrove leaves in Taiwan for 24 saturated and unsaturated fatty acids in their mycelia. This paper is the first to report C18:1n-7 vaccenic acid, C20:1 eicosenoic acid, C24:1 nervonic acid, C20:2n-6 eicosadienoic acid, C22:4n-6 adrenic acid, C20:4n-3 eicosatetraenoic acid and C22:5n-3 docosapentaenoic acid in mycelia of
and
species, and the fatty acid profiles of
and
. Five fatty acids were dominant in the mycelia of the isolates, i.e. C16:0 palmitic acid, C18:1n-9 oleic acid, C18:2n-6 linoleic acid, C20:4n-6 arachidonic acid and C20:5n-3 eicosapentaenoic acid. For the essential fatty acids,
produced the highest level of arachidonic acid (27–31% of total fatty acid (TFA), 141–188 mg l
yield) while
IMB212 produced the highest percentage of EPA (15% of TFA) while
IMB227 produced the highest yield (96 mg l
). Different species and isolates of the same species produced different fatty acid profiles, and further research effort may yield a high production isolate of industrial significance and also important fatty acids from the marine environment.
The classification of subclass
Xylariomycetidae
is revisited with additional collections and phylogeny based on novel rDNA sequence data. Phylogenetic inferences are provided and are based on ...analysis of 115 sequence data, including new data for 27 strains. An updated outline to the subclass is presented based on the phylogenies and comprises two orders, 18 families and 222 genera. An account of each order, family and genus in the subclass is given. We accept the orders
Amphisphaeriales
and
Xylariales
based on morphological and phylogenetic evidence.
Amphisphaeriales
comprises
Amphisphaeriaceae
,
Bartaliniaceae
fam. nov.,
Clypeosphaeriaceae
,
Discosiaceae
fam. nov.,
Pestalotiopsidaceae
fam. nov. and
Phlogicylindriaceae
fam. nov.
Xylariales
comprises
Apiosporaceae
,
Cainiaceae
,
Coniocessiaceae
,
Diatrypaceae
,
Graphostromataceae
(doubtful),
Hyponectriaceae
,
Iodosphaeriaceae
,
Lopadostomaceae
fam. nov.,
Melogrammataceae
,
Pseudomassariaceae
fam. nov.,
Vialaeaceae
and
Xylariaceae
. The new genera and species introduced are
Arthrinium hyphopodii
,
A. subglobosa
,
Cainia anthoxanthis
,
Ciferriascosea
gen. nov.,
C. fluctamurum
,
C. rectamurum
,
Discosia neofraxinea
,
D. pseudopleurochaeta
,
Hyalotiella rubi
,
Seimatosporium cornii
,
S. ficeae
,
S. vitis
and
Truncatella spartii
.
Bovine respiratory syncytial virus, a major cause of respiratory disease in calves, is closely related to human RSV, a leading cause of respiratory disease in infants. Recently, promising human ...RSV-vaccine candidates have been engineered that stabilize the metastable fusion (F) glycoprotein in its prefusion state; however, the absence of a relevant animal model for human RSV has complicated assessment of these vaccine candidates. Here, we use a combination of structure-based design, antigenic characterization, and X-ray crystallography to translate human RSV F stabilization into the bovine context. A "DS2" version of bovine respiratory syncytial virus F with subunits covalently fused, fusion peptide removed, and pre-fusion conformation stabilized by cavity-filling mutations and intra- and inter-protomer disulfides was recognized by pre-fusion-specific antibodies, AM14, D25, and MPE8, and elicited bovine respiratory syncytial virus-neutralizing titers in calves >100-fold higher than those elicited by post-fusion F. When challenged with a heterologous bovine respiratory syncytial virus, virus was not detected in nasal secretions nor in respiratory tract samples of DS2-immunized calves; by contrast bovine respiratory syncytial virus was detected in all post-fusion- and placebo-immunized calves. Our results demonstrate proof-of-concept that DS2-stabilized RSV F immunogens can induce highly protective immunity from RSV in a native host with implications for the efficacy of prefusion-stabilized F vaccines in humans and for the prevention of bovine respiratory syncytial virus in calves.
Hot Jupiters are rarely accompanied by other planets within a factor of a few in orbital distance. Previously, only two such systems have been found. Here, we report the discovery of a third system ...using data from the Transiting Exoplanet Survey Satellite (TESS). The host star, TOI-1130, is an eleventh magnitude K-dwarf in Gaia G-band. It has two transiting planets: a Neptune-sized planet (3.65 0.10 ) with a 4.1 days period, and a hot Jupiter ( ) with an 8.4 days period. Precise radial-velocity observations show that the mass of the hot Jupiter is . For the inner Neptune, the data provide only an upper limit on the mass of 0.17 (3 ). Nevertheless, we are confident that the inner planet is real, based on follow-up ground-based photometry and adaptive-optics imaging that rule out other plausible sources of the TESS transit signal. The unusual planetary architecture of and the brightness of the host star make TOI-1130 a good test case for planet formation theories, and an attractive target for future spectroscopic observations.
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