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zadetkov: 103
1.
  • Regulation of germinal cent... Regulation of germinal center B-cell differentiation
    Zhang, Yang; Garcia-Ibanez, Laura; Toellner, Kai-Michael Immunological reviews, March 2016, Letnik: 270, Številka: 1
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    Summary Germinal centers (GC) are the main sites where antigen‐activated B‐cell clones expand and undergo immunoglobulin gene hypermutation and selection. Iterations of this process will lead to ...
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Dostopno za: UL

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2.
  • Plasma cell output from ger... Plasma cell output from germinal centers is regulated by signals from Tfh and stromal cells
    Zhang, Yang; Tech, Laura; George, Laura A ... The Journal of experimental medicine, 04/2018, Letnik: 215, Številka: 4
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    Germinal centers (GCs) are the sites where B cells undergo affinity maturation. The regulation of cellular output from the GC is not well understood. Here, we show that from the earliest stages of ...
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Dostopno za: UL

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3.
  • Class-Switch Recombination ... Class-Switch Recombination Occurs Infrequently in Germinal Centers
    Roco, Jonathan A.; Mesin, Luka; Binder, Sebastian C. ... Immunity (Cambridge, Mass.), 08/2019, Letnik: 51, Številka: 2
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    Class-switch recombination (CSR) is a DNA recombination process that replaces the immunoglobulin (Ig) constant region for the isotype that can best protect against the pathogen. Dysregulation of CSR ...
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Dostopno za: UL

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4.
  • Germinal center derived B c... Germinal center derived B cell memory without T cells
    Zhang, Yang; Toellner, Kai-Michael The Journal of experimental medicine, 03/2022, Letnik: 219, Številka: 3
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    Liu et al. (2022. J. Exp. Med.https://doi.org/10.1084/jem.20210527) in this issue show that T cell-independent germinal centers (GCs) can produce long-lived memory and plasma cell output. This may ...
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Dostopno za: UL
5.
  • IL-21 regulates germinal ce... IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism
    Zotos, Dimitra; Coquet, Jonathan M; Zhang, Yang ... The Journal of experimental medicine, 02/2010, Letnik: 207, Številka: 2
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    Germinal centers (GCs) are sites of B cell proliferation, somatic hypermutation, and selection of variants with improved affinity for antigen. Long-lived memory B cells and plasma cells are also ...
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Dostopno za: UL

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6.
  • Cytokine mRNA profiling ide... Cytokine mRNA profiling identifies B cells as a major source of RANKL in rheumatoid arthritis
    Yeo, Lorraine; Toellner, Kai-Michael; Salmon, Mike ... Annals of the rheumatic diseases, 11/2011, Letnik: 70, Številka: 11
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    Objectives In rheumatoid arthritis (RA), a complex cytokine network drives chronic inflammation and joint destruction. So far, few attempts have been made to identify the cellular sources of ...
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Dostopno za: CMK, UL

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7.
  • IL-22 regulates lymphoid ch... IL-22 regulates lymphoid chemokine production and assembly of tertiary lymphoid organs
    Barone, Francesca; Nayar, Saba; Campos, Joana ... Proceedings of the National Academy of Sciences - PNAS, 09/2015, Letnik: 112, Številka: 35
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    The series of events leading to tertiary lymphoid organ (TLO) formation in mucosal organs following tissue damage remain unclear. Using a virus-induced model of autoantibody formation in the salivary ...
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Dostopno za: UL

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8.
  • Selective Expression of Flt... Selective Expression of Flt3 within the Mouse Hematopoietic Stem Cell Compartment
    Mooney, Ciaran James; Cunningham, Alan; Tsapogas, Panagiotis ... International journal of molecular sciences, 05/2017, Letnik: 18, Številka: 5
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    The fms-like tyrosine kinase 3 (Flt3) is a cell surface receptor that is expressed by various hematopoietic progenitor cells (HPC) and Flt3-activating mutations are commonly present in acute myeloid ...
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Dostopno za: UL

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9.
  • Nr4a1 and Nr4a3 Reporter Mi... Nr4a1 and Nr4a3 Reporter Mice Are Differentially Sensitive to T Cell Receptor Signal Strength and Duration
    Jennings, Emma; Elliot, Thomas A.E.; Thawait, Natasha ... Cell reports (Cambridge), 11/2020, Letnik: 33, Številka: 5
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    Nr4a receptors are activated by T cell receptor (TCR) signaling and play key roles in T cell differentiation. Which TCR signaling pathways regulate Nr4a receptors and their sensitivities to TCR ...
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Dostopno za: UL

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10.
  • Cognate interactions: Extra... Cognate interactions: Extrafollicular IL‐4 drives germinal‐center reactions, a new role for an old cytokine
    Toellner, Kai‐Michael European journal of immunology, July 2014, Letnik: 44, Številka: 7
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    Over the past 25 years it has become clear that B and T lymphocytes go through a range of interactions and migratory events when B cells differentiate to become high‐affinity, antibody‐secreting ...
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Dostopno za: UL

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zadetkov: 103

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