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Provider: - Institution: - Data provided by Europeana Collections- All metadata published by Europeana are available free of restriction under the Creative Commons CC0 1.0 Universal Public Domain ...Dedication. However, Europeana requests that you actively acknowledge and give attribution to all metadata sources including Europeana
Epidemiological studies on the association between Turner syndrome (TS) and Graves' disease (GD) are sparse and no studies are available on the clinical course of GD in TS.
To retrospectively ...investigate the GD prevalence in children and young adults with TS and to compare the GD course in patients with or without TS who were followed up for 4.1 ± 0.6 and 4.5 ± 3.7 years, respectively.
The prevalence of GD in 408 TS patients was evaluated; presentation and evolution of GD under therapy were evaluated both in 7 patients with TS (group A) and in 89 patients without TS (group B).
(a) The prevalence of GD in TS patients was 1.7%; (b) GD in TS was not associated with a specific karyotype; (c) with respect to group B patients, those of group A exhibited at presentation more advanced age, a lower fT4 level and more frequent association with other autoimmune diseases, and (d) the clinical course under methimazole therapy was not different in the two groups.
The prevalence of GD in children and young adults with TS is 1.7% and in TS patients, GD presents later and its clinical course is not different than in those without TS.
The 5th INTEGRAL Workshop: "The INTEGRAL Universe", February
16-20, 2004, Allemagne (2004) We report the results of extensive high-energy observations of the X-ray
transient and black hole candidate ...XTE J1720-318 performed with INTEGRAL,
XMM-Newton and RXTE. The source, which underwent an outburst in January 2003,
was observed in February in a spectral state dominated by a soft component with
a weak high-energy tail. The XMM-Newton data provided a high column density Nh
of 1.2*e22 cm^{-2} which suggests that the source lies at the Galactic Center
distance. The simultaneous RXTE and INTEGRAL Target of Opportunity observations
allowed us to measure the weak and steep tail, typical of a black-hole binary
in the so-called High/Soft State. We could follow the evolution of the source
outburst over several months using the INTEGRAL Galactic Center survey
observations. The source regained activity at the end of March: it showed a
clear transition towards a much harder state, and then decayed to a quiescent
state in summer. In the hard state, the source was detected up to 200 keV with
a typical power law index of 1.8 and a peak luminosity of 7.5*e36 ergs s^{-1}
in the 2-100 keV band, for an assumed distance of 8 kpc. We conclude that XTE
J1720-318 is indeed representative of the class of the black hole X-ray novae
which populate our Galactic bulge and we discuss its properties in the frame of
the spectral models used for transient black hole binaries.
We report the results of extensive high-energy observations of the X-ray transient and black hole candidate XTE J1720-318 performed with INTEGRAL, XMM-Newton and RXTE. The source, which underwent an ...outburst in January 2003, was observed in February in a spectral state dominated by a soft component with a weak high-energy tail. The XMM-Newton data provided a high column density Nh of 1.2*e22 cm^{-2} which suggests that the source lies at the Galactic Center distance. The simultaneous RXTE and INTEGRAL Target of Opportunity observations allowed us to measure the weak and steep tail, typical of a black-hole binary in the so-called High/Soft State. We could follow the evolution of the source outburst over several months using the INTEGRAL Galactic Center survey observations. The source regained activity at the end of March: it showed a clear transition towards a much harder state, and then decayed to a quiescent state in summer. In the hard state, the source was detected up to 200 keV with a typical power law index of 1.8 and a peak luminosity of 7.5*e36 ergs s^{-1} in the 2-100 keV band, for an assumed distance of 8 kpc. We conclude that XTE J1720-318 is indeed representative of the class of the black hole X-ray novae which populate our Galactic bulge and we discuss its properties in the frame of the spectral models used for transient black hole binaries.
