The efficiency in the management of patients with suspected malignant lesions represents the main objective of the oncology of head and neck. Flexible nasopahyngolaryngoscopy with working channel ...allows to quickly and safely assess and obtain histological samples of this type of lesion. Our objective is to describe the usefulness of this technique in lesions suggestive of malignancy in terms of efficiency, sensitivity and specificity. A retrospective study was carried out over a period of time from December 2014 to December 2019, including patients biopsied with flexible fibroscopy of lesions of debut suspected of malignancy. Here we assess the location of the lesion, the histological results, the diagnostic time and the epidemiological variables. 104 patients were included in the study. More than half of the lesions, 55.2% (57), were located in the larynx; 57.7% (60) resulted positive for malignancy in the flexible fiberscope biopsy; 19.2% (20) were taken to the operating room to get biopsied under general anesthesia resulting in 7.4% (14) positive for malignancy, which shows a sensitivity of the test of 81%. In our sample, a diagnostic time of 15 days was obtained. Considering our results, the few complications and the revised literature, flexible fiberscope biopsy with working channel is an efficient procedure for the management of oncological patients of head and neck.
Sixty percent of prelingual hearing loss is of genetic origin. A family history of permanent childhood hearing loss is a risk factor. The objective of the study is to determine the relationship ...between this risk factor and hearing loss. We have evaluated clinical and epidemiological characteristics and related nonsyndromic genetic variation.
This was a retrospective, descriptive and observational study of newborns between January 2007 and December 2010 with family history as risk factor for hearing loss using transient evoked otoacoustic emissions and auditory brainstem response.
A total of 26,717 children were born. Eight hundred and fifty-seven (3.2%) had family history. Fifty-seven(0.21%) failed to pass the second test. A percentage of 29.1 (n=16) had another risk factor, and 17.8% (n=9) had no classical risk factor. No risk factor was related to the hearing loss except heart disease. Seventy-six point four percent had normal hearing and 23.6% hearing loss. The mean of family members with hearing loss was 1.25. On genetic testing, 82.86% of homozygotes was normal, 11.43% heterozygosity in Connexin 26 gene (35delG), 2.86% R143W heterozygosity in the same gene and 2.86% mutant homozygotes (35delG). We found no relationship between hearing loss and mutated allele.
The percentage of children with a family history and hearing loss is higher than expected in the general population. The genetic profile requires updating to clarify the relationship between hearing loss and heart disease, family history and the low prevalence in the mutations analyzed.
INTRODUCTION AND OBJECTIVESixty percent of prelingual hearing loss is of genetic origin. A family history of permanent childhood hearing loss is a risk factor. The objective of the study is to ...determine the relationship between this risk factor and hearing loss. We have evaluated clinical and epidemiological characteristics and related nonsyndromic genetic variation. MATERIAL AND METHODThis was a retrospective, descriptive and observational study of newborns between January 2007 and December 2010 with family history as risk factor for hearing loss using transient evoked otoacoustic emissions and auditory brainstem response. RESULTSA total of 26,717 children were born. Eight hundred and fifty-seven (3.2%) had family history. Fifty-seven(0.21%) failed to pass the second test. A percentage of 29.1 (n=16) had another risk factor, and 17.8% (n=9) had no classical risk factor. No risk factor was related to the hearing loss except heart disease. Seventy-six point four percent had normal hearing and 23.6% hearing loss. The mean of family members with hearing loss was 1.25. On genetic testing, 82.86% of homozygotes was normal, 11.43% heterozygosity in Connexin 26 gene (35delG), 2.86% R143W heterozygosity in the same gene and 2.86% mutant homozygotes (35delG). We found no relationship between hearing loss and mutated allele. CONCLUSIONSThe percentage of children with a family history and hearing loss is higher than expected in the general population. The genetic profile requires updating to clarify the relationship between hearing loss and heart disease, family history and the low prevalence in the mutations analyzed.
El facilitador en la universalización de la enseñanza Gutiérrez Chiguanto, Edsel; Quintana Marrero, Annia; Pérez González, Fé Mercedes ...
Revista de Ciencias Médicas de Pinar del Río,
06/2007, Letnik:
11, Številka:
2
Journal Article
Recenzirano
Odprti dostop
La educación cubana constituye un ejemplo para muchos países del mundo. Las transformaciones en la misma se caracterizan por proponer, a partir de la unión entre la teoría y la práctica, modelos ...pedagógicos que constituyen realidades para nuestro pueblo, mientras para otras lamentablemente ahora son sueños inalcanzables. Tal es el caso de la universalización de la educación superior y la municipalización que es relativamente nuevo. Se habla sobre algunas características del Modelo Pedagógico adoptado en la Universalización y sobre el papel del Tutor como elemento más novedoso en este Modelo, los atributos del tutor como esencia en la formación de los nuevos profesionales que trabajaran en nuestra sociedad. Para lograr la efectividad y buenos resultados debemos preparar un proyecto de acción tutorial individualizado para cada estudiante teniendo en cuenta sus características individuales.
La educación cubana constituye un ejemplo para muchos países del mundo. Las transformaciones en la misma se caracterizan por proponer, a partir de la unión entre la teoría y la práctica, modelos ...pedagógicos que constituyen realidades para nuestro pueblo, mientras para otras lamentablemente ahora son sueños inalcanzables. Tal es el caso de la universalización de la educación superior y la municipalización que es relativamente nuevo. Se habla sobre algunas características del Modelo Pedagógico adoptado en la Universalización y sobre el papel del Tutor como elemento más novedoso en este Modelo, los atributos del tutor como esencia en la formación de los nuevos profesionales que trabajaran en nuestra sociedad. Para lograr la efectividad y buenos resultados debemos preparar un proyecto de acción tutorial individualizado para cada estudiante teniendo en cuenta sus características individuales.Cuban education is an example for many countries in the world. Its transformations are characterized by proposing, from uniting theory and practice, pedagogical models which are realities for our people, whereas for others, unfortunately, they are now unreachable dreams. Such is the case of the universalization in higher education and the municipalization which is relatively new. Some characteristics of the Pedagogical Model adopted and the Mentor's role as most novel element in this Model are approached, as well as the mentor's attributes as the essence in the formation of new professionals who work in our society. To accomplish the effectiveness and good results, we should prepare an individualized mentoral action project for each student, considering its individual characteristics.
